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Öğe Auditory function after spinal anaesthesia: the effect of differently designed spinal needles(LIPPINCOTT WILLIAMS & WILKINS, 2009) Erol, Atilla; Topal, Ahmet; Arbag, Hamdi; Kilicaslan, Alper; Reisli, Ruhiye; Otelcioglu, SerefBackground and objective Recurrent, bilateral or unilateral, persistent or transient, mild or profound hearing loss has been reported after spinal anaesthesia. We studied the effects of the needle type (Quincke, ballpen, pencil-point spinal needles) on hearing loss after spinal anaesthesia with the use of pure-tone audiometry. Methods Forty-five ASA physical status 1 patients scheduled for elective inguinal herniorraphy with spinal anaesthesia were enrolled in the study. The patients were randomly divided into three groups. Group Q (n = 15) patients received spinal anaesthesia through a 25-gauge (G) Quincke spinal needle, group B (n = 15) patients received the same through a 25-G ballpen spinal needle and those in group P (n = 15) received the same through a 25-G pencil-point spinal needle. Patients were interviewed about postoperative complaints such as postdural puncture headache, vertigo, nausea-vomiting, transient neurological symptoms and major neurological deficits. Pure-tone audiometry was performed by an audiologist at specific time intervals. Results The number of patients who had greater than 10 dB hearing loss in group Q was significantly more than that found in group B and group P at 250, 500, 4000 and 6000 Hz on postoperative day 1. When group B and group P were compared for change in hearing, no statistically significant difference was detected at any frequency tested. Conclusion Because the use of ballpen and pencil-point needles reduces hearing loss after spinal anaesthesia, these needles are preferred. Eur J Anaesthesiol 26:416-420 (c) 2009 European Society of Anaesthesiology.Öğe Comparative evaluation of different miniplates for internal fixation of mandible fractures using finite element analysis(W B SAUNDERS CO-ELSEVIER INC, 2008) Arbag, Hamdi; Korkmaz, Hasan Huesnue; Ozturk, Kayhan; Uyar, YavuzPurpose: In this computer-based study, finite element analysis (FEA) was performed to assess the most suitable shape and fixation technique for a certain type of mandible fracture at corpus. Materials and Methods: A model of the mandible was prepared using computed tomography (CT) scans. The CT scans were transferred and converted to the finite element model by means of a procedure developed for this study. Simulated corpus fractures were fixed with 14 different fixation configurations of titanium miniplates. The FEA was performed with respect to displacement and stresses in the titanium miniplates for these configurations. Results: The study results indicated that the use of 2 straight miniplates is more rigid than other fixation types. Fixation with only I miniplate at the inferior location resulted in mobility greater than the set limit of 150 mu m. With "L" and "T" shaped miniplates and a straight miniplate at the middle location, fracture mobility was approximately equal to or less than the limit; however, displacement nearly reached to limit. Superior fixations with only 1 miniplate resulted in mobility lower than the limit. But these configurations exceed the yield limit of titanium miniplate. Conclusions: FEA may be useful in evaluation of other plate constructs, fracture types, and fracture sites, as confirmed by the agreement between our data and those in the literature and with clinical experience. This analysis should permit us to suggest and evaluate new miniplate designs and enable considerable savings to be made in terms of time, material, and animal experiments in the future development of osteosynthesis materials and techniques. (C) 2008 American Association of Oral and Maxillofacial Surgeons.Öğe The effects of early and late feeding on healing of esophageal anastomoses: An experimental study(ELSEVIER IRELAND LTD, 2011) Yurtcu, Muslim; Toy, Hatice; Arbag, Hamdi; Caglayan, OsmanObjective: To investigate the effects of postoperative late and early feeding on the healing of experimental esophageal anastomosis (EA). Methods: Twelve New Zealand rabbits were divided equally into 2 groups: late feeding (LF) and early feeding (EF). A 1-cm-length of the cervical esophagus was resected through a cervical incision, and then anastomosis was performed. The LF group was fed parenterally for 6 days and orally (per oral route) after esophagography on postoperative day 7 as long as there was no esophageal leakage. The EF group was fed orally (per oral route) 24 h after esophageal repairs (ERs), and esophagography was carried out on postoperative day 7 to check the ERs. The rabbits were sacrificed to evaluate bursting pressure (BP), diameter of the esophageal lumen (DOTEL), tissue hydroxyproline (HP), and wound healing scores (WHSs) in the anastomosis lines 8 weeks later. Results: In the LF group, BP and DOTEL were significantly lower than they were in the EF group, and HP was significantly higher than it was in the EF group. WHSs in the LF group were not higher than they were in the EFgroup. Conclusions: Early feeding is superior after EA as shown by increased DOTEL and BP levels, but causes decreased HP levels. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Öğe Evaluation of HLA-A, -B, -Cw, and -DRB1 alleles frequency in Turkish patients with nasal polyposis(SAGE PUBLICATIONS LTD, 2008) Keles, Bahar; Cora, Tuelin; Acar, Hasan; Arbag, Hamdi; Inan, Ziya; Ozturk, Kayhan; Ozer, BedriOBJECTIVE: To evaluate whether there is a relationship between HLA-A, -B, -Cw, and -DRB1 alleles and developing nasal polyposis (NP). STUDY DESIGN: Data from 66 patients with NP were compared with data from 100 healthy randomly selected controls. Asthma, ASA (acetylsalicylic acid) triad, polyp score, and previous sinonasal surgery were also recorded. SUBJECTS AND METHODS: Genotyping of the HLA-A, -B, -Cw, and -DRB1 alleles were performed with polymerase chain reaction (PCR) with the sequence-specific primer (SSP) method. Data were analyzed by using a Pearson chi(2) test. RESULTS: The HLA-B*07 and -Cw*12 alleles were found to be significantly higher in the NP patients compared with the control group, whereas the HLA-B*57 and HLA-Cw*04 alleles were significantly lower (P < 0.05). The HLA-A*24, HLA-Cw*12, and HLA-DRB1*04 alleles were determined to be significantly higher in the NP patients with asthma and ASA triad (P < 0.05). CONCLUSIONS: Our results show that some of the HLA alleles seem to be associated with the genetic susceptibility to develop NP in the Turkish population. (C) 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.Öğe Evaluation of the effects of nasal septal deviation and its surgery on nasal mucociliary clearance in both nasal cavities(OCEAN SIDE PUBLICATIONS INC, 2007) Ulusoy, Bulent; Arbag, Hamdi; Sari, Oktay; Yoendemli, FuatBackground: In this study the effects of nasal septal deviation (NSD) and its surgery on nasal mucociliary clearance velocity (NMCV) in both nasal cavities were evaluated. Methods: This study included 20 patients with NSD and 20 healthy subjects as a control group who had no complaint related to the nose. NMCV was measured with rhinoscintigraphy using technetium-99m-macroaggregated albumin (Tc-99m-MAA). Results: Before the septal surgery, the NMCV of concave (10.24 +/- 3.96 mm/minute) and convex sides (10.78 +/- 3.53 mm/minute) of the patients were significantly lower than the control group (17.94 +/- 2.89 mm/minute). There is no statistically significant difference between the NMCV of the concave and convex sides. After septal surgery, the NMCVs of the concave (16.34 +/- 4.40 mm/minute) and convex sides (17.21 +/- 3.43 mm/minute) were not significantly different from control groups (17.94 +/- 2.89 mm/minute). Postoperative NMCVs of the concave and convex sides was significantly better than preoperative NMCVs. Conclusion: The results of this study showed that NSD significantly impaired NMCVs in both sides and that septoplasty significantly improved NMCVs in both sides.Öğe Inferior Concha Bullosa with Bilaterally Concha Hypertropy(MODESTUM LTD, 2015) Yuca, Koksal; Varsak, Y. Kursad; Eryilmaz, Mehmet Akif; Arbag, HamdiInferior concha bullosa is an extremely rare anatomic malformation. Unlike other turbinates of the nasal cavity Inferior turbinate is a separate bone. Although inferior concha bullosa is generally asymptomatic and diagnosed incidentally by computed tomography. Nasal obstruction, headache, epiphora, rhinorrhoea, and dysosmia are some of the possible symptoms. We report the case of a 37- year- old white woman with right inferior concha bullosa and bilaterally inferior turbinate hypertropy. We discuss and report this rare condition under literature.Öğe A Modified Technique for Bypass of the External Carotid Artery to the Proximal Posterior Cerebral Artery: An Anatomical and Technical Study(Taylor & Francis as, 2006) Öztürk, Kayhan; Uysal, İlknur İsmihan; Arbag, Hamdi; Büyükmumcu, Mustafa; Üstün, Mehmet Erkan; Salbacak, AhmetConclusions. Our results support the proposition that bypass between the external carotid artery (ECA) and proximal posterior cerebral artery (PCA) can be achieved by using a short saphenous venous graft. The diameters of the ECA and vein graft may provide an increased blood flow with a straighter course. This technique may be helpful for management of patients with vertebrobasilar insufficiency or those requiring a high volume blood flow to the posterior circulation. Objectives. We aimed to describe a modified technique using a short saphenous vein graft for bypass between the ECA and the PCA in order to use a small length of graft material and increase the patency of the anastomosis. Materials and methods. Ten sides of five cadavers were dissected bilaterally. After a frontotemporal craniotomy and zygomatic arch osteotomy, the middle cranial fossa was exposed. A hole located approximately 2 - 3 cm posterolateral to the foramen rotundum was created extradurally. The sylvian fissure and the interpedincular and ambient cisterns were opened. The proximal P2 segment of the PCA was identified. The ECA was found through a cervical incision. A short interposition saphenous vein graft was conducted to pass just behind the ramus mandible to the infratemporal fossa. The bypass between the ECA and P2 segment of the PCA was performed by using a short saphenous vein graft. The diameters of the ECA, P2 segment of PCA and both ends of the saphenous vein graft and its length were measured using an electronic micrometer. Results. The mean cross-clamping time of the PCA was 10.4 +/- 1.8 min. The mean diameters of the P2 segment of the PCA and ECA were 2.2 +/- 0.15 mm and 3.83 +/- 0.28 mm, respectively. The mean length of the saphenous vein graft was 88.8 +/- 3.8 mm.Öğe Pulmonary arterial pressure in children with croup syndrome(W B SAUNDERS CO-ELSEVIER INC, 2006) Oran, Buelent; Ekici, Guelsuen; Reisli, Ismail; Arbag, Hamdi; Baspinar, Osman; Baysal, Tamer; Dogan, MustafaPurpose: Croup syndrome or laryngotracheitis is one of the frequent causes of transient upper airway obstruction by laryngeal and tracheal blockage in infants and children. Upper airway obstruction may lead to increased pulmonary arterial pressure in children. In this study, the relationship between croup syndrome and pulmonary arterial pressure was investigated. Materials and methods: Forty children with croup syndrome and 14 healthy, age- and sex-matched control Subjects were enrolled in this study. Of all patients, 12 with severe symptoms, such as dyspnea, cyanosis, hypoventilation, were accepted as "high croup score" (croup score >= 6). All patients with high croup score were treated with dexamethasone. We assessed pulmonary arterial pressure of patients during therapy using serial echocardiographic measurements. Results: Our results showed that children with croup syndrome have significantly higher pulmonary arterial pressures than healthy subjects at the time of diagnosis. Pressure values of patients with high croup score were found to be significantly higher when compared with those of the low -core group (P < .05). However, there was no difference between 2 groups at the end of therapy. Conclusions: It is Suggested that pulmonary arterial pressure increased to different extents in the acute stage of illness and that the degree of increase was related to the severity of disease and average hospital stay. In addition, increased pulmonary arterial pressure due to croup syndrome is reversible. Furthermore, evaluation of children with croup syndrome by using Doppler echocardiography may be useful in the monitoring of pulmonary arterial pressure and in the follow-up of their therapy. (C) 2006 Elsevier Inc. All rights reserved.Öğe Pulmonary arterial pressure in infants with laryngomalacia(ELSEVIER IRELAND LTD, 2006) Unal, Ekrem; Oran, Bulent; Baysal, Tamer; Baspinar, Osman; Keser, Melike; Karaarslan, Sevim; Arbag, HamdiObjective: Persistent upper airway obstruction may lead to increased pulmonary arterial pressure in childhood. Laryngomalacia is one of the most common causes of transient upper airway obstruction by laryngeal blockage in infants. The aim of the study is to evaluate the pulmonary arterial pressures in infants with laryngomalacia during infancy period. Methods: Fifteen infants with laryngomalacia and 30 healthy controls were enrolled into this study. The pulmonary arterial pressures were measured by using Doppler echocardiography. Infants were also evaluated by clinical investigations, telecardiography and electrocardiography. Results: Our results showed that infants with laryngomalacia may have significantly higher pulmonary arterial pressure than healthy subjects. Pressures of patient group were significantly decreased at the end of infancy period. Conclusions:. Increased pulmonary arterial pressure levels due to laryngomalacia are reversible by during developmental process. Therefore, in symptomatic period, evaluation of infants with laryngomalacia by using Doppler echocardiography may be useful for monitoring pulmonary arterial pressure and following up the clinical outcome. (C) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe Role of diffusion weighted MR in the discrimination diagnosis of the cystic and/or necrotic head and neck lesions(ELSEVIER IRELAND LTD, 2007) Koc, Osman; Paksoy, Yahya; Erayman, Ibrahim; Kivrak, Ali Sami; Arbag, HamdiPurpose: The purpose was to determine whether the diffusion weighted imaging (DWI) was able to differentiate necrotic tumor or metastatic lesions from infected necrotic lesions such as abscesses and necrotic lymphadenitis in the neck. Materials and methods: DWI was performed on 37 consecutive patients with 85 head and neck necrotic and cystic lesions. The lesions were classified into four categories: metastatic lymph node involvement including lymphoma, necrotic tumor, abscesses and necrotic lymphadenitis. Each lesion was histopathologically studied and proved. Results: In 12 patients, there were 35 necrotic lymphadenitis (necrotic tuberculosis lymphadenitis, n = 18; necrotic nonspecific suppurative lymphadenitis, n = 17). Of the 15 necrotic metastatic nodes, 11 lesions were lymphomatous involvement and 4 lesions were other tumor involvement. Other 11 patients have abscesses. Thirteen primary tumoral necrotic lesions arose in the neck of nine patients. All of the abscesses and necrotic lympadenitis showed hyperintensity on DWI, in contrast to necrotic tumor and necrotic nodal metastasis that showed hypointensity on DWI. DWI successfully differentiated metastatic nodes and necrotic tumors from necrotic lymphadenitis and abscesses. Conclusion: DWI may be supportive for differentiating necrotic tumor lesions such as necrotic tumor and metastatic necrotic nodes from the infective necrotic lesions such as necrotic lymphadenitis and abscesses in the head and neck. (c) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe Single seventh day debridement compared to frequent debridement after endoscopic sinus surgery: a randomized controlled trial(SPRINGER, 2016) Varsak, Yasin Kursad; Yuca, Koksal; Eryilmaz, Mehmet Akif; Arbag, HamdiThe aim of this study was to evaluate the postoperative debridement frequency following endoscopic sinus surgery. Individual randomized controlled trial. Sixty-two adult patients with a diagnosis of chronic rhino sinusitis (CRS) with nasal polyps (NP) and CRS without NP meeting the inclusion criteria were enrolled in this prospective study. The patients were randomized equally to frequent debridement (FD; at postoperative weeks 1, 2 and 4) or to a single debridement (SD; at postoperative week 1) after surgery. The outcomes were assessed with visual analog scale (VAS) for nine main symptoms concerning patient discomfort within the first 4 weeks, with the modified Lund-Kennedy endoscopic score (MLKES) at weeks 4 and 24 and with the sino-nasal outcome test-20 (SNOT-20) at week 24. Thirty-seven of the patients were male, and twenty-five were female. The mean age was 36.1 +/- 13.5 in FD group and 39.2 +/- 14.7 in SD group. In the SD group, the VAS scores at postoperative week four showed significantly less discomfort at visits (p = 0.004) and less negative effects on their work (p = 0.013). There was no statistically significant difference between the two groups in the week 4 and 24 MLKES and in the week 24 SNOT-20 scores (p > 0.05). The endoscopic findings did not show significant differences between the groups. Our data indicate that FD causes more discomfort at the required visits, more facial pain and more negative effects on patients' work; this method is not superior to postoperative single seventh day debridement in terms of the 24-week quality of life and endoscopic scores.Öğe Surgical management with or without a nasogastric tube in esophageal repairs(ELSEVIER IRELAND LTD, 2012) Yurtcu, Muslim; Toy, Hatice; Arbag, Hamdi; Caglayan, OsmanObjective: The aim of the study was to compare surgical management with or without a nasogastric tube (NGT) to prevent anastomotic stricture that occurred following esophageal repairs (ERs). Methods: Twelve New Zealand rabbits were divided equally into 2 m: with a NGT (experimental group) and without a NGT (control group). A 1-cm-length of the cervical esophagus was resected through a cervical incision and then anastomosis was performed using the NGT and keeping it in place for 6 days in the experimental group. The same procedures were performed in the control group. Both groups were fed parenterally for 6 days and orally after esophagography on postoperative day 7 as long as there was no esophageal leakage. The rabbits were sacrificed to evaluate diameter of the esophageal lumen (DOTEL), bursting pressure (BP), tissue hydroxyproline (HP) and wound healing scores (WHSs) in the anastomosis lines 8 weeks later. Results: In the experimental group, DOTEL, BP, and HP were significantly lower than they were in the control group. WHSs in the experimental group were not higher than they were in the control group. Conclusions: Surgical management without a NGT is more effective than management with a NGT in ERs as shown by increased DOTEL, BP, and HP levels. (C) 2011 Elsevier Ireland Ltd. All rights reserved.Öğe Tympanoplasty in pediatric patients(ELSEVIER IRELAND LTD, 2006) Uyar, Yavuz; Keles, Bahar; Koc, Sema; Oeztuerk, Kayhan; Arbag, HamdiObjective: The aim of this study is to analyze the clinical features and follow-up of a series of pediatric patients with chronic otitis media undergoing tymponaplasty surgery and to identify the effect of the factors on the course. Methods: Forty-one children (mean age 15.1 +/- 2.62 years, range from 8 to 16 years) who had undergone tympanoplasty with or without ossicular reconstruction were evaluated. Age, gender, size and site of perforation, status of operated ear (dry/ discharging), status of the contralateral ear, underlying cause of the perforations, surgical technique, preoperative and postoperative hearing levels, average postoperative follow-up time, and postoperative complications were recorded. Results: Myringoplasty in 28 patients (68.3%), incus interposition in 7 patients (17.1%), partial ossicular replacement prostheses in 4 patients (9.7%) and total ossicular replacement prostheses in 2 patients (4.9%) were performed. In the 37 (90.2%) of patients, intact graft was determined during postoperative follow-up. Surgical success including intact graft and postoperative air-bone gap of less than 25 dB were obtained in 34 (82.9%) cases. Conclusions: The present study suggested that tympanoplasty was a quite successful method in the appropriate pediatric patients between the ages of 8 and 16 years. In the preoperative evaluation for surgery success, some factors, such as dry middle ear, healthy contralateral ear and concordant to postoperative care should be considered. (C) 2006 Elsevier Ireland Ltd. All rights reserved.