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    Bitümlü sıcak karışımlara ait akma değerinin regresyon modelleri İle tahmini
    (2018) Bayırtepe, Hikmet; Arslan, Deniz
    Bu çalışmada, bitümlü sıcak karışım özelliklerinden olan ve Marshall Testi ile deneysel olarak belirlenebilen akma değerinin malzeme ve karışım özellikleri temelinde regresyon modelleri ile tahmin edilmesi amaçlanmıştır. Bu kapsamda Ankara Büyükşehir Belediyesi sınırları dahilindeki aşınma ve binder tabakalarının inşaatına yönelik bitümlü sıcak karışım uygulamalarına ait veriler derlenmiş ve uygulama temelinde 4680 adet gözlem içeren veri grubu oluşturulmuştur. Veri grubuna regresyon, temel bileşen, kümeleme ve diskriminant analizleri uygulanmıştır. Kümeleme analizi, veri grubunun 4 ana kümeye ayrılabileceğini göstermiştir. Belirlenen kümelere ve çeşitli kombinasyonlarına uygulanan standart aşamalı regresyon analizleri ile akma bağımlı değişkenini tahmin etmek üzere geliştirilen modellerde regresyon katsayısı % 73,9'a kadar ulaşmıştır
  • Küçük Resim Yok
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    Clinicopathologic Features and Molecular Subtypes of Breast Cancer in Young Women (Age <= 35)
    (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014) Goksu, Sema Sezgin; Tastekin, Didem; Arslan, Deniz; Gunduz, Seyda; Tatli, Ali Murat; Unal, Dilek; Salim, Derya
    Introduction: Breast cancer in young women is a relatively rare disease; however it tends to be more aggressive and is the leading cause of cancer death in this population. The aim of this study is to investigate the clinical and biological features of breast cancer arising in young Turkish breast cancer patients. Materials and Methods: Patients with breast cancer aged 35 or less (<= 35 years) were selected for the study. In total 211 cases were included. Pathologic features; histologic subtypes, grade, lymphovascular invasion, axillary involvement, and stage were recorded for each. Results: The most common subtype was luminal B (36.5%), followed by luminal A (30.8%), triple negative (23.2%) and HER2+(9.5%) subtypes. Twelve percent of the patients had stage 4, 32.7% had stage 3, 46.4% had stage 2, and 6.2% had stage 1 disease at the time of diagnosis. Mean tumour diameter was 3.87 cm (range 0.3-13 cm). The axillary lymph nodes were positive in 74.4% of the patients, while lympho-vascular invasion was seen in 56.4%. Some 9.5% of patients had grade 1, 51.2% had grade 2, and 31.8% had grade 3 tumors. Conclusions: Young women with breast cancer in Turkey are more likely to present with luminal B subtype. Tumors in young women are more likely to present with advanced disease, to be high grade and and to have more lymphovascular invasion. Further research should focus on whether we need new treatment strategies for young patients with breast carcinoma.
  • Küçük Resim Yok
    Öğe
    Survival results and prognostic factors in T4 N0-3 non-small cell lung cancer patients according to the AJCC 7th edition staging system.
    (AMER SOC CLINICAL ONCOLOGY, 2013) Arslan, Deniz; Bozcuk, Hakan Sat; Tatli, Ali Murat; Gunduz, Seyda; Uysal, Mukremin; Goksu, Sema Sezgin; Koral, Lokman
    [Abstract not Available]