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    The impact of obsessive-compulsive disorder in pregnancy on quality of life
    (TAYLOR & FRANCIS LTD, 2008) Gezginc, Kazim; Uguz, Faruk; Karatayli, Savas; Zeytinci, Esra; Askin, Ruestem; Gueler, Oezkan; Sahin, Figen
    Aim. To examine the effects of obsessive-compulsive disorder (OCD) on quality of life in pregnant women. Material and method. Twenty-five pregnant women diagnosed as OCD in two university outpatient clinics were included for the study. Twenty-five pregnant women with no mental disorders and the same sociodemographic properties were taken as the control group. The diagnosis of OCD was confirmed with the DSM-IV Axis-I Disorders Structured Clinic Interview Diagnosis/Clinic Version (SCID-I/CV). In order to measure the severity of OCD Yale-Brown Obsession and Compulsion Scale was performed. Quality of life was evaluated by WHO (World Health Organisation) Life Quality Scale - Short Form (WHOQOL-Brief). Results. The whole subgroup of points of WHOQOL-Brief was significantly lower in OCD patients compared to control group (in all subgroups P < 0.01). There was a negative correlation between the Y-BOCS obsession and compulsion subpoints and total points with the physical health (P < 0.05), psychological health (P < 0.001) and social relationship (P < 0.01) of WHOQOL-Brief. No significant association was found with enviromental areas. Besides, there was a negative correlation between the duration of OCD and WHOQOL-Brief psychological health subarea (P < 0.05). Conclusion. OCD negatively effects the quality of life in pregnant women and is correlated with the severity of the disorder.
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    Sociodemographic and clinical characteristics in patients with obsessive-compulsive disorder with and without comorbid obsessive-compulsive personality disorder
    (CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2009) Uguz, Faruk; Besiroglu, Luefullah; Askin, Ruestem
    Objective: In this study, we aimed to investigate sociodemographic and clinical characteristics in patients with obsessive-compulsive disorder (OCD) with and without comorbid obsessive-compulsive personality disorder (OCPD). Methods: This study was conducted among patients who were admitted to outpatients clinics of department of psychiatry of 2 different university hospitals. The study sample consisted of 30 OCD outpatients with only OCPD among the Axis II disorders and 38 OCD patients without any Axis II disorders. Axis I and Axis II psychiatric disorders were determined by means of the Structured Clinical Interview for DSM-IV/Clinical Version (SCID-I/CV) and the Structured Clinical Interview for DSM-III-R Personality Disorders (SCID-II), respectively. The Yale-Brown Obsessive- Compulsive Scale (Y-BOCS) was used to determine types and severity of obsessive-compulsive symptoms. The patients' insight degree on obsessive-compulsive symptoms was assessed by means of the item 11 on the Y-BOCS. Results: The study groups had similar characteristics with respect to age, sex, educational level, marital status, and employment status. Compared to OCD patients without OCPD, symmetry/exactness obsessions, ordering/arranging compulsions, and diagnoses of comorbid major depression, dysthymic disorder, generalized anxiety disorder and social phobia were found to be significantly more frequent in OCD patients with OCPD. There was no significant difference between study groups in terms of other types and severity of obsessive-compulsive symptoms, other comorbid axis I disorders, age at onset and duration of OCD, and the patients' insight degree. Conclusion: The study results suggest that OCD patients with and without comorbid OCPD have generally similar sociodemographic and clinical characteristics. (Anatolian Journal of Psychiatry 2009; 10: 5-10)