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    Case presentation: Approach to acute rheumatic fever patient with hepatotoxicity due to acetylsalicylic acid [Bir olgu eşliğinde asetilsalisilik asite bağlı karaciğer toksisitesi gelişen akut romatizmal ateş hastasına yaklaşım]
    (Galenos Yayincilik,, 2017) Güvenç O.; Çimen D.; Aslan E.; Emiroğlu H.; Arslan D.; Oran B.
    Treatment with acetylsalicylic acid is the first choice for arthritis and mild carditis of acute rheumatic fever which is a common disease in our country. There may be many adverse reactions during treatment. 10 year-old male patient diagnosed as acute rheumatic fever had hepatotoxicity due to acetylsalicylic acid therapy. This clinic manifestation has the possibility that can be seen always in pediatric cardiology practice.This case is presented due to limited literature on the treatment of patients with hepatotoxicity. © 2017, Galenos Yayincilik. All rights reserved.
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    Facile preparation of amorphous NiWSex and CoWSex nanoparticles for the electrocatalytic hydrogen evolution reaction in alkaline condition
    (Elsevier B.V., 2020) Aslan E.; Sarilmaz A.; Yanalak G.; Chang C.S.; Cinar I.; Ozel F.; Patir I.H.
    The development of catalysts as an alternative to platinum group metals (PGMs) has great importance to improve the efficiency of hydrogen evolution reaction (HER). Herein, the novel amorphous ternary refractory metal selenides (MWSex; M = Co and Ni), which were synthesized by hot-injection approach, were firstly investigated on the electrocatalytic HER in alkaline media. Optical, electrochemical and magnetic properties of the electrocatalysts were explored, as well as the chemical structures and morphologies. These results clearly show that the obtained materials are having the amorphous crystal structure and are shaped as spherical and rod-like structures. Moreover, the addition of Ni and Co metals into the WSex structure were raised the catalytic activity of HER comparing to that of only WSex. This work paves the way for the exploration of copper-based amorphous selenides as electrocatalysts for the hydrogen evolution in order to replace noble metal Pt. © 2019 Elsevier B.V.
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    Photocatalytic hydrogen evolution reaction activity comparable to 1-D nanofiber materials exhibited by the kesterite nanorods catalysts
    (Elsevier Ltd, 2020) Yanalak G.; Sarılmaz A.; Aslan E.; Ozel F.; Patir I.H.
    Copper-based earth-abundant chalcogenides (kesterite) such as Cu2CoSnS4 and Cu2NiSnS4 are important class due to their outstanding performance and earth-abundant composition. Here, we have successfully synthesized Cu2CoSnS4, Cu2NiSnS4 and Cu2ZnSnS4 nanorods by a hot-injection technique. The photocatalytic hydrogen production activities of rod-like Cu2XSnS4 (X = Co, Ni and Zn) catalysts have been investigated by using electron donor triethanolamine and photosensitizer eosin-Y under visible-light irradiation. The hydrogen evolution rates for the nanorods change in the order of Cu2NiSnS4> Cu2CoSnS4> Cu2ZnSnS4 (5117 ?molg?1h?1, 1342 ?molg?1h?1 and 719 ?molg?1h?1) respectively. The hydrogen evolution activities of Cu2XSnS4 nanorods have been compared to that of nanofiber and nanodot forms of Cu2XSnS4 catalysts. Cu2XSnS4 nanorods have been showed comparable photocatalytic activity for the hydrogen evolution compared with 1-D nanofiber Cu2XSnS4 catalysts. © 2020 Elsevier Ltd
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    Port of Kalpe in the Bithynian region [Bithynia Bölgesi? Kalpe li?mani]
    (2014) Aslan E.
    The ancient port of Kalpe is located in the Black Sea coast of Bithynia (in the Kocaeli Province, Kandira town of Kerpe). "Kalpe Harbour" was initially mentioned in the Anabasis of Xenophon. Today, the blocks of the breakwater construction are distributed in the north end of the Bay of Kerpe and are partially on land being mostly submerged; they are spread over a wide area of approximately 80 m. in length and 36 m. in width. However, five in situ stone blocks rest on the bedrock on the shore; furthermore the breakwater blocks under the sourrounding wall of the modern teahouse on the shore are also in situ. This port in the north-eastern end of the Kerpe bay was constructed in the protruding end of the mainland in northeast - southwest direction. Although not well preserved, in the light of available data the architecture, building techniques and the approximate measures of the port of Kalpe can be calculated. The area of construction and the run of the breakwater was planned to serve the loading and unloading of ancient ships by preventing the prevailing northern winds in the region and offering shelter at the same time. In terms of the period to which it belongs, its location and its building technique this port forms an important example for the ancient ports and for the ports of the Black Sea where as the restitution of its breakwater can be largely undertaken in line with the available data.
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    A rare disease: Mucopolysaccharidosis type 6 and cardiac involvement: Case Report [Nadir Görölen Bir Hastalik: Mukopolisakkaridoz Tip 6 ve Kalp Tutulumu]
    (Turkiye Klinikleri, 2015) Gövenç O.; Çimen D.; Arslan D.; Aslan E.; Oran B.
    Mucopolysaccharidosis type 6, also known as Maroteaux-Lamy syndrome, is a rare, multisystemic, progressive disease characterized by somatic involvement of varying severity and normal intelligence. N-Acetylgalactosamine-4-sulfatase enzyme is lacking and disfunction at cell, tissue, and organ levels occurs due to dermatan sulfate accumulation. Besides the findings such as coarse facial appearance, hydrocephalus, dysostosis multiplex, corneal opacity, hepatosplenomegaly, and joint stiffness, cardiac involvement is also frequently observed. Valvular heart disease, cardiomyopathy, and arrhythmia may occur in patients. In this article, we presented and discussed a mucopolysaccharidosis type 6 patient having moderate mitral valve regurgitation together with dextrocardia as a case in the light of recent literature. © Copyright 2015 by Turkiye Klinikleri.
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    Urine darkening disease: Alkaptonuria [İdrarı Siyahlaşltıran Hastalık: Alkaptonüri]
    (Galenos Yayincilik,, 2010) Aslan E.; Yavuz H.
    Introduction: Alkaptonuria is a disease caused by deficiency of homogentisate 1-2 dioxygenase, which is associated with thyrosine metabolism in the liver. Deficiency of this enzyme is caused by mutation in homogentisic acid oxidase gene. This is a rare otosomal recessive disease. The most prominent symptom in childhood is darkening of urine in a few hours. Arthritis, ochronotic pigmentation in sclera and ear and degeneration of mitral or aortic valves are the characteristics of this disease, which are usually seen in older than thirty-year-old people. There is no curative therapy, but nitisinone is the only currently used drug in this disease. However, there is no definite information about when this treatment should be started how much time is needed for this treatment to be carried on, and what probable side-effects can occur. Case Report: We reported a 4-year-old girl patient diagnosed as alkaptonuria who had underclothes coloration and darkening urine. Conclusion: We aim to highlight to darkening urine which is the most encountered manifestation of alkaptonuria in childhood. Alkaptonuria may cause serious complications in the future. © The Journal of Current Pediatrics, published by Galenos Publishing.