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    An artificial intelligence solution for reduce complications at tissue expansion [Doku genişlemesinde komplikasyonlari azaltmaya yönelik yapay bir zeka çözümü]
    (Institute of Electrical and Electronics Engineers Inc., 2019) Ugurlutan R.; Ayaz M.
    In this study, a robust artificial intelligence system which aims to minimize the common complications in the application of balloon plasty method which has been used for more than half a century and its application is explained. The system was tested as a prototype on new zealand rabbits for twenty days and 1 of the 6 subjects was excluded from the study due to a lack of literature and 5 of them were successful. In general, the structure of the system, working algorithm and data from the subjects are summarized. © 2019 IEEE.
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    Controlled trial of efficacy of dexketoprofen in sciatic nerve crush injury in rats [Si{dotless}çanlarda siyatik sinir yaralanmasi{dotless}nda deksketoprofenin etkinli?inin kontrollü çali{dotless}şmasi{dotless}]
    (Ege University Press, 2014) Kaptan H.; Kasimcan O.; Ayaz M.; Bozdogan O.; Karabagli H.
    Object: Local applications of Dexketoprofen trometamol (dex) have been shown to increase in the sciatic nerve functional tests following the nerve injuries. The aim of the current study was to compare the efficacy of dex application for 1 and 5 days following nerve injury rat model. Possible effects of dex were checked by means of the Sciatic Function Index (SFI), Withdrawal of the Reflex Leg (WRL), number of axons, axon diameter, and nerve diameters. Material Methods: The animal crushed model was done through Aesculap -Yasargil aneurysm method on Wistar albino (N=21) right sciatic nerves. In order to achieve desired purpose 3 experimental groups were organized: Group 1: control (injured and no drug); Group2: dexketoprofen 1 days (injured and single dose of drug); Group3: dexketoprofen 5 days (injured and single dose of 5 times drug applications). Injections were done through the tissue expander's injection port with a connecting tube directed at the crush-injured site. Functional recovery of the sciatic nerves was evaluated with the improvement in the SFI values. Additionally, recovery of sensory function was assessed through WRL results and histopathological examination was performed 6 week following the injury. Results: At the end of the experimental periods there was no significant differences were found between the experimental group of animals on the bases of the number of axons, axon diameter, and nerve diameter. Moreover, up 30th day of the experimental period our functional test results have shown that there was no difference between the groups. But following the induction of the injury, the statistical significances were seen on the functional tests. This effect was seen only if the multi-dose application of the dex. Conclusions: This study suggests that; dexketoprofen trometamol of 5 consecutive days, has revealed positive significant changes in the sciatic nerve injury through analgesic effect of it.
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    Effect transformation of the Micro Electrode Recording (MER) data to Fast Fourier Transform (FFT) for the main target nucleus determination for STN-DBS
    (Avicena Publishing, 2014) Kaptan H.; Ayaz M.; Ekmekçi H.
    Introduction: Advanced PD stimulation of the STN reduces tremor, rigidity, and bradykinesia. Due to hemorrhagic complications the use of micro electrode recordings during DBS operation was still questioning for some of surgeons. But use micro electrodes were still the best choice for the positioning during surgery of DBS. Aim: The aim of the current study was to investigate the effect transformation of the micro electrode recording data to fast fourier transform for the main target nucleus determination. This process needs a multidisciplinary approach from neurosurgery, neurology and specialists on electrophysiology such as biophysics. Case report: We present the case of a 63 year-old male with medically intractable PD is focused on behalf of the surgical treatment. Patient had a 4-year history of progressively severe hand tremor on right side. The patient was successfully treated unilaterally with the STN DBS. © AVICENA 2014.
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    Selenium controlled diabetic cardiomyopathy complications
    (Oriental Scientific Publishing Company, 2017) Ayaz M.; Yanardag S.B.; Unal N.A.
    Secondary complications of diabetes develop gradually in longer terms. The longer you have diabetes the higher the risk and severity of the complications. Sooner or later, diabetes induced complications may result in the paucity of the physiological functions of the body which in turn give rise to life-threatening situations.Although we need small quantities still selenium plays a key role in the body metabolism. Indeed, having an antioxidant characteristic, it protects many cell types from damage especially during chronic diseases. © 2018 Termedia Publishing House Ltd. All rights reserved.