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    Comparison of the sealing ability of biodentine, iroot bp plus and mineral trioxide aggregate
    (Cumhuriyet University Faculty of Dentistry, 2016) Aydemir S.; Cimilli H.; Gemi P.M.; Bozkurt A.; Orucoglu H.; Chandler N.; Kartal N.
    Objective: The aim of this study was to compare the sealing ability of two new root repair materials, Biodentine and iRoot BP Plus against ProRoot MTA when used as root-end fillings. Methods: The root canals of 45 extracted maxillary anterior teeth were prepared with Pro Taper instruments. After apical resection and ultrasonic root-end cavity preparation, the teeth were divided into three groups. The cavities in the first group of 15 were filled with Biodentine, the second with iRoot BP Plus and the third with ProRoot MTA. A computerized fluid filtration method assessed the seal at 2, 10 and 28 days. Results: Significant differences were found between Groups 1-2, Groups 1-3 and between Groups 2-3 at all-time intervals (P < 0.05). Leakage was not significantly different at 10 and 28 days for Biodentine and iRoot BP Plus (P > 0.05). Conclusion: The two new root repair materials showed good performance and both offered improved handling properties compared to MTA. © 2016, Cumhuriyet Dent J. All rights reserved.
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    Effects of milk somatic cell counts on some physicochemical and functional characteristics of skim and whole milk powders
    (Elsevier Inc., 2016) Sert D.; Mercan E.; Aydemir S.; Civelek M.
    The aim of this work was to study the influence of milk somatic cell count (SCC) levels on spray-dried milk powders. For this reason, 3 cow milks with different SCC (<300,000, 300,000-700,000, >700,000 SCC/mL) were processed into skim (SMP) and whole milk powder (WMP). The effect of SCC on the physicochemical and functional characteristics of the milk powders and textural properties of set-type yogurts produced from reconstituted milk powders with different SCC was evaluated. A crucial difference was noted between milk powders depending on different SCC. Protein values and ash content of powder samples decreased correlatively with increasing SCC. The hydroxymethylfurfural content of SMP was higher than WMP. We noted an increase in hydroxymethylfurfural content of both SMP and WMP depending on elevated SCC. Solubility index of SMP and WMP was 1.280 to 1.632 and 0.940 to 1.208 mL, respectively; with increasing SCC, solubility index was affected adversely. The highest foam stability was determined in SMP containing >700,000 SCC. Bulk density of SMP and WMP was between 0.682 and 0.708 and 0.660 to 0.685 g/cm3, respectively. An increase was observed in scorched particle of both SMP and WMP depending on increasing SCC. We found significant differences in particle size distribution of milk powders produced from milk with SCC at different levels. Although WMP had more uniform and big particle structure, SMP had more specific area. A negative correlation was noted between yogurt texture and SCC. Results indicate that milk SCC has negative influences on milk powder quality. © 2016 American Dairy Science Association.
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    Synthesis and evaluation of antioxidant, antimicrobial and anticancer properties of 2-(prop-2-yn-1-yloxy)benzaldehyde derivatives
    (Bentham Science Publishers B.V., 2019) Konus M.; Aydemir S.; Yilmaz C.; Kivrak A.; Kizildogan A.K.; Arpaci P.U.
    5-bromo-2-(prop-2-yn-1-yloxy)benzaldehyde (compound 3) and 3,5-di-tert-butyl-2-(prop-2- yn-1-yloxy)benzaldehyde (compound 5) were synthesized via nucleophilic substitution reactions. Compound 5 showed higher antioxidant capacity with respect to compound 3 in all the four different antioxidant activity methods used. Moreover, in phosphomolybdenum assay, compound 5, with 1.1 proportion value, showed almost the same total antioxidant capacity compared to universal trolox standard. Furthermore, Broth microdilution method and agar disc diffusion tests demonstrated that the same compound also exhibited good antibacterial activity towards the bacteria Bacillus subtilis. Finally, both of the benzaldehyde compounds showed high antifungal activity against Aspergillus niger. In this study, compound 5 (IC50: 54.3 µg/ml) showed significant cytotoxic activity against breast adenocarcinoma cell line MCF-7 with respect to compound 3 (IC50: 173.4 µg/ml). © 2019 Bentham Science Publishers.