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    Are psychiatric outpatients assessed for smoking?
    (DUZCE UNIV, 2017) Ertekin, Hulya; Aydin, Memduha; Arslan, Mehmet; Ertekin, Yusuf Haydar; Eren, Ibrahim
    Objectives: The presence of psychiatric disorder is not obstacle for the treatment to quit smoking; however this treatment is not preferred among primary purposes in these patients. We aimed to investigate use of tobacco, whether asked their smoking habit by a psychiatrist, the request of patients who smoke to quit smoking, whether they can get help from the psychiatric outpatient clinic of knowledge about smoking cessation and "Addiction and Treatment of Smoking" training of the psychiatrists effects on query of smoking status. Methods: This study was conducted at Outpatient Clinic of the Beyhekim Department of Psychiatry at Konya Education and Research Hospital between June and July 2013. Five-item questionnaire was administered to all participants after the examination in the first phase.. The outpatient clinic doctors were not informed about the questionnaire during examination because of alteration their interrogation of smoking. In September 2013, "Addiction and Treatment of Smoking" training were given to the psychiatrists doctors working in this study. In the second phase of this study, same questionnaire was administrated to patients of these trained doctors.. Results: 51.1% of participants were smokers. In the first phase of the study, doctors from the 18.3% (n=40) and 53.5% (n = 95) in the second phase had questioned smoking of patients. After training seminar the rate to question of doctors had significantly increased (p<0.001). % 37.9 of participants (n=69) wanted to quit smoking. % 46.9 of participants (n=186) knew that they can get help from the psychiatric outpatient clinic for smoking cessation. Conclusion: "Chance to get rid of smoking addiction" should be offered to patients in psychiatric outpatient clinics. Working to increase the knowledge of psychiatrics on this subject should be made.
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    Neutrophil/lymphocyte ratio, monocyte/lymphocyte ratio, and mean platelet volume as systemic inflammatory markers in different states of bipolar disorder
    (TAYLOR & FRANCIS LTD, 2019) Inanli, Ikbal; Aydin, Memduha; Caliskan, Ali Metehan; Eren, Ibrahim
    Background: Currently, increasing evidence supports the hypothesis that alterations in the immune-inflammatory system are critical for the pathophysiology of bipolar disorder (BD). Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR), and mean platelet volume (MPV) have recently been investigated as inexpensive and simple inflammatory markers. Aims: The aim of this study is to compare NLR, PLR, MLR, and MPV in depressive, manic, and euthymic patients with BD and healthy controls, and to evaluate whether values of NLR, PLR, MLR, and MPV are possible state or trait biomarkers in BD. Methods: This retrospective study was conducted with 341 patients with BD (100 patients in a depressive state, 141 patients in a manic state, and 100 patients in a euthymic state) and 114 healthy controls. Results: We found that patients with BD in manic states had higher levels of MPV, NLR, and MLR, and patients with BD in depressive states had higher levels of MPV than the controls. Moreover, MPV predicted all states of BD, while NLR and MLR predicted the manic state of BD. Conclusions: NLR, MLR, and MPV obtained from simple and inexpensive blood tests were significantly higher in patients with BD than in healthy controls, which each imply low-grade inflammation. MPV may serve as a possible trait biomarker of BD, while NLR and MLR may both serve as possible state biomarkers of the manic state.