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  • Küçük Resim
    Öğe
    The clinical and pathological features of patients with gastric cancer in Turkey: A Turkish oncology group study
    (2006) Yalçın, Bülent; Zengin N.; Aydın, Faruk; İlhan, Mahmut; Işıkdoğan, A.; Demir, Güneş; Aykan, Nuri Faruk; Çelik, İsmail; Dane, F.; Üstüner, Zeynep; Börüban M. C.; Bozcuk H.; Coşkun H. Ş.; Karaoğlu A.; Altınbaş M.; Yamaç D.; Tek, İbrahim; Budakoğlu B.; Utkan G.; Özdemir, Feza; Aksoy, Sercan; Özdemir, Nuriye Yıldırım; Akbulut, Hakan; Büyükçelik, Abdullah; İçli, Fikri
    Although the incidence of gastric cancer has declined dramatically in western countries; it is, after the breast cancer in women and lung cancer in men, the second most common cancer in Turkey with a high mortality. Surgery is the mainstay in the management of gastric cancer, and unresectable disease has poor prognosis. The aim of this study was to evaluate the clinicopathological and epidemiological features of patients with gastric cancer in Turkey. A questionnaire was used to collect information on clinicopathological and socioeconomic features of all patients with newly diagnosed gastric cancer in contributing 16 different centers in Turkey in the year 2004. The findings were analyzed by the geographic regions in patients live. Nine-hundred seventy-one patients with newly diagnosed gastric cancer in 2004 were included in the study. Mean age of the patients was 57±12.9 (mean±SD) years. Male-female ratio was 2/1. The rate of cancer resectability was lower in Eastern Turkey (ET) than Western Turkey (WT) (31.6% vs. 63.4%, p=0.0001). Also, socioeconomic status of the patients was lowest in ET (53.6% vs. 32.3%, p=0.0001). H. pylori gastritis and intestinal metaplasia were more common in ET when compared to WT (75.0% vs. 40.5%; p=0.003, and 68.4% vs. 18.1%; p=0.0001, respectively). Lower resectability rate of disease in ET should be appreciated. Further epidemiological study of gastric cancer is warranted in Turkey.
  • Küçük Resim Yok
    Öğe
    Epidemiology of colorectal cancer in Turkey: A cross-sectional disease registry study (A Turkish Oncology Group trial)
    (AVES, 2015) Aykan, Nuri Faruk; Yalcin, Suayib; Turhal, N. Serdar; Ozdogan, Mustafa; Demir, Gokhan; Ozkan, Metin; Yaren, Arzu
    Background/Aims: This study aimed to determine the epidemiological characteristics of colorectal cancer in Turkey. Materials and Methods: In this multicenter, prospective, and cross-sectional registry study, data for 968 patients with colorectal cancer from 21 centers in 7 geographic regions were analyzed. Results: Diagnosis was colon cancer in 662 (68.4%) and rectum cancer in 306 (31.6%) patients. In total, 60.9% of patients was male; mean age was 58.9 +/- 12.6 years. Among patients, 15.0% was drinking alcohol, 17.5% was smoking, 1.5% had familial history of polyposis, 15.0% had diabetes mellitus, 1.0% had inflammatory bowel disease. Fruit and vegetable consumption was low (<3 times/week) in 35.5% and red meat consumption was high (>= 3 times/week) in 47.4% of the patients. Median time-to diagnosis was 3.0 months and 4.0 months for patients with colon and rectum cancer, respectively. Mean body mass index was >25 in all group of patients. Distal rectum (61.3%) and sigmoid colon (36.8%) were the most common locations of cancer, for rectum and colon respectively. In total, 85.6% of patients were operated; 25.8% had emergency surgery. Low anterior resection rate was 64.2% in rectum cancer. In majority (89.8%) of the patients with rectum cancer who received preoperative treatment, conventional chemo-radiotherapy regimen was given. pTNM staging at diagnosis showed that stage III and IV patients were in majority (35.9% and 29.7%, respectively). Conclusion: Colon cancer is more frequent than rectum cancer in Turkey. Colorectal cancer patients are diagnosed at later stages. Most of the cases were operated. Interregional differences for risk factors are worthwhile for evaluation in future trials.