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Öğe Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: Results of aggregate and individual patient data meta-analyses(LIPPINCOTT WILLIAMS & WILKINS, 2019) Ovadia, Caroline; Seed, Paul T.; Sklavounos, Alexandros; Geenes, Victoria; Di Illio, Chiara; Chambers, Jenny; Kohari, Katherine; Bacq, Yannick; Bozkurt, Nuray; Brun-Furrer, Romana; Bull, Laura; Estiú, Maria C.; Grymowicz, Monika; Günaydın, Berrin; Hague, William M.; Haslinger, Christian; Hu, Yayi; Kawakita, Tetsuya; Kebapcılar, Ayşe Gül; Kebapcılar, Levent; Kondrackienė, Jūratė; Koster, Maria P. H.; Kowalska-Kańka, Aneta; Kupčinskas, Limas; Lee, Richard H.; Locatelli, Anna; Macias, Rocio I. R.; Marschall, Hanns-Ulrich; Oudijk, Martijn A.; Raz, Yael; Rimon, Eli; Shan, Dan; Tribe, Rachel; Tripodi, Valeria; Abide, Çiğdem Yayla; Yenidede, İlter; Thornton, Jim G.; Chappell, Lucy C.; Williamson, Catherine; Shao, YongIntrahepatic cholestasis of pregnancy (ICP) affects less than 0.1% to 0.2% of pregnant women. It is diagnosed in women with gestational pruritus and increased serum bile acids and can be complicated by preterm labor, fetal asphyxia, meconium-stained amniotic fluid, and stillbirth.