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Öğe Lung perfusion scintigraphy in patients with Behcet's disease(SPRINGER, 2005) Sari, O.; Balevi, S.; Serdengecti, M.[Abstract not Available]Öğe Meibomian Gland Dysfunction and Tear Film Abnormalities in Rosacea(LIPPINCOTT-RAVEN PUBL, 1995) Zengin, N.; Tol, H.; Gündüz, K.; Okudan, S.; Balevi, S.; Endoğru, HIn order to determine the relationship between meibomian gland dysfunction and tear film abnormalities in rosacea, tear film flow and stability and meibomian gland function were assessed in 43 consecutive patients. Schirmer, tear film break-up time, and meibomian gland function values in patients with ocular rosacea (n=28) were found to be significantly decreased as compared with those of the patients with only cutaneous involvement and control patients (p>0.05). In patients with dermatologic rosacea (n=15) these values were not different from those of the age- and sex-matched controls (p>0.05). The effects of tetracycline and meibomian gland expression therapy were also investigated in patients with ocular rosacea. Neither meibomian gland expression therapy nor tetracycline administration had beneficial effects on decreased tear secretion, but tetracycline improved the break-up time values. Our findings showed a positive relationship between tear film abnormalities and meibomian gland dysfunction in patients with rosacea. Decreased tear secretion in patients with ocular rosacea would seem to be a result of structural changes secondary to meibomian gland dysfunction, and short break-up time might be due to an abnormal meibum composition.Öğe Pathergy reaction in different body areas in Behcet's disease(BLACKWELL PUBLISHING, 2007) Ozdemir, M.; Balevi, S.; Deniz, F.; Mevlitoglu, I.Behcet's disease (BD) is a chronic inflammatory multisystemic disorder characterized mainly by vasculitis. Although the pathergy reaction (PR) has been accepted as one of the major criteria in this disease, there is a lack of a standardized method to measure PR. The aim of this study was to evaluate results of PR in different body areas and the effect on the positive rate of PR of application of numerous needle pricks. The pathergy test was performed using simultaneous 16 needle pricks with 20G disposable needles on different body areas of 56 patients with BD, 49 patients with recurrent aphthous stomatitis (RAS) and 17 healthy subjects. No positive PR was found in healthy controls, but was observed in nine patients with RAS (18.3%). It was detected in 48 of 56 patients with BD, a positive rate of 85.7%. The site most frequently positive for PR was the forearm, while the least frequent was the abdomen. Multiple needle pricks could play an important role in increasing the positive rate of PR in BD, and it may be important in the investigation of aetiological factors in RAS.
