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Öğe Prevalence and distribution of children with congenital heart diseases in the central Anatolian region, Turkey(TURKISH J PEDIATRICS, 2006) Baspinar, Osman; Karaaslan, Sevim; Oran, Buelent; Baysal, Tamer; Elmaci, A. Midhat; Yorulmaz, AlaaddinCongenital heart diseases (CHD) are the most frequent malformation at birth. The aims of this study were to assess the prevalence of congenital heart disease, their different types, and the detection rate among children in the central Anatolian region in Turkey. The study was conducted during an eight-year period (March 1995-December 2002). The prevalence of CHD in a large tertiary care hospital in the central Anatolian region in Turkey was studied. The diagnosis of a structural defect was based on echocardiographic study. The following age groups were considered: neonates, infants and toddlers, preschool children, schoolchildren, and adolescents. In the study period, 1,693 children were found to have CHD; 1,253 patients were neonates and infants. Total prevalence of CHD over the study period was 7.77 per 1,000 live-born. The prevalence increased from 6.35 to 9.65 per 1,000 live births between 1995 and 2002 (p<0.05). The average age at diagnosis was 2.2+/-3.64 years (I day to 18 years, median 5 months). There were 863 (51%) boys and 830 (49%) girls, with a male/female ratio of 1:1. Isolated ventricular septal defect (32.6%) was the most frequent acyanotic anomaly, and tetralogy of Fallot (5.8%) was the most frequent cyanotic anomaly. The commonest non-cardiac anomalies with CHD were musculoskeletal. anomalies. Down syndrome was determined in 83 patients (78.3%) from all syndromic CHD cases. Congenital heart disease is a very significant health problem. It requires urgent measures in terms of organization of early diagnosis and proper management. The prevalence rate is comparable to that of similar developed countries. Increasing incidence of CHD might be attributed to more diagnoses with new technologic development or it may indicate a real increase in the defects.Öğe Pulmonary arterial pressure in children with croup syndrome(W B SAUNDERS CO-ELSEVIER INC, 2006) Oran, Buelent; Ekici, Guelsuen; Reisli, Ismail; Arbag, Hamdi; Baspinar, Osman; Baysal, Tamer; Dogan, MustafaPurpose: Croup syndrome or laryngotracheitis is one of the frequent causes of transient upper airway obstruction by laryngeal and tracheal blockage in infants and children. Upper airway obstruction may lead to increased pulmonary arterial pressure in children. In this study, the relationship between croup syndrome and pulmonary arterial pressure was investigated. Materials and methods: Forty children with croup syndrome and 14 healthy, age- and sex-matched control Subjects were enrolled in this study. Of all patients, 12 with severe symptoms, such as dyspnea, cyanosis, hypoventilation, were accepted as "high croup score" (croup score >= 6). All patients with high croup score were treated with dexamethasone. We assessed pulmonary arterial pressure of patients during therapy using serial echocardiographic measurements. Results: Our results showed that children with croup syndrome have significantly higher pulmonary arterial pressures than healthy subjects at the time of diagnosis. Pressure values of patients with high croup score were found to be significantly higher when compared with those of the low -core group (P < .05). However, there was no difference between 2 groups at the end of therapy. Conclusions: It is Suggested that pulmonary arterial pressure increased to different extents in the acute stage of illness and that the degree of increase was related to the severity of disease and average hospital stay. In addition, increased pulmonary arterial pressure due to croup syndrome is reversible. Furthermore, evaluation of children with croup syndrome by using Doppler echocardiography may be useful in the monitoring of pulmonary arterial pressure and in the follow-up of their therapy. (C) 2006 Elsevier Inc. All rights reserved.Öğe Pulmonary arterial pressure in infants with laryngomalacia(ELSEVIER IRELAND LTD, 2006) Unal, Ekrem; Oran, Bulent; Baysal, Tamer; Baspinar, Osman; Keser, Melike; Karaarslan, Sevim; Arbag, HamdiObjective: Persistent upper airway obstruction may lead to increased pulmonary arterial pressure in childhood. Laryngomalacia is one of the most common causes of transient upper airway obstruction by laryngeal blockage in infants. The aim of the study is to evaluate the pulmonary arterial pressures in infants with laryngomalacia during infancy period. Methods: Fifteen infants with laryngomalacia and 30 healthy controls were enrolled into this study. The pulmonary arterial pressures were measured by using Doppler echocardiography. Infants were also evaluated by clinical investigations, telecardiography and electrocardiography. Results: Our results showed that infants with laryngomalacia may have significantly higher pulmonary arterial pressure than healthy subjects. Pressures of patient group were significantly decreased at the end of infancy period. Conclusions:. Increased pulmonary arterial pressure levels due to laryngomalacia are reversible by during developmental process. Therefore, in symptomatic period, evaluation of infants with laryngomalacia by using Doppler echocardiography may be useful for monitoring pulmonary arterial pressure and following up the clinical outcome. (C) 2006 Elsevier Ireland Ltd. All rights reserved.