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Öğe THE EFFECTS OF ANEMIA AND RED CELL TRANSFUSION ON THE RISK OF MORTALITY AMONG GERIATRIC AND NON-GERIATRIC PATIENTS WITH HOSPITAL-ACQUIRED INFECTIONS IN AN INTENSIVE CARE UNIT(GUNES KITABEVI LTD STI, 2015) Kutlucan, Leyla; Kutlucan, Ali; Basturk, Abdulkadir; Kandis, Hayati; Titiz, Hafize; Senocak, Elif; Dagli, MehmetIntroduction: This study aimed to investigate the effects of anemia and red blood cell transfusion on the risk of mortality in geriatric and non-geriatric Intensive Care Unit patients with Hospital-Acquired Infection. Materials and Method: This study included 546 patients aged >= 18 years; from these, 112 patients had Hospital-Acquired Infection. Results: Among the patients aged >= 65 years with Hospital-Acquired Infection who were treated in the medical Intensive Care Unit, the risk of mortality was significantly increased in patients with anemia or history of diabetes; in patients who were intubated or in patients with neurological disorders or respiratory failure. Although the abovementioned factors increased the risk of mortality in the elderly, the same relationship was not observed in patients aged<65 years. In addition, blood transfusion did not increase the risk of mortality in patients belonging to both the age groups. Conclusion: We conclude that in geriatric Intensive Care Unit patients with Hospital-Acquired Infection, anemia increases the risk of mortality but red cell transfusion does not affect the risk of mortality.Öğe Neutropenia Due to Acute Exposure with Aluminium Phosphide(MODESTUM LTD, 2015) Kutlucan, Ali; Dagli, Mehmet; Kutlucan, Leyla; Basturk, Abdulkadir[Abstract not Available]Öğe SEVERE HYPERBILIRUBINEMIA DURING FAMILYAL MEDITERRANEAN FEVER ATTACK IN PATIENTS WITH GILBERT'S SYNDROME(ISTANBUL UNIV, FACULTY MEDICINE, PUBLISHING OFFICE, 2016) Kutlu, Orkide; Keskin, Muharrem; Basturk, Abdulkadir; Ecirli, Samil; Bilgic, Yilmaz; Fisekci Oktar, SevilFamilial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by fever and accompanying attacks of serositis. Cytokines such as IL-6, TNF-alpha, IL-1 beta are known to play an active role in FMF pathogenesis. Gilbert's syndrome, is a clinical condition that results indirect hyperbilirubinemia during febrile illness, surgery, vomiting and prolonged fasting period because of inhibition of UDP-glucuronide transferase activity. Increased bilirubin levels during FMF attack is caused suppression of UDP-glucuronide transferase activity by cytokines involved in the pathogenesis of FMF. Here, we report a patient who had serious indirect bilirubin elevation during an attack of FMF.