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Öğe Demographic, clinical and management characteristics of newly diagnosed COPD patients in Turkey: A real-life study(DOVE MEDICAL PRESS LTD, 2020) Süerdem, Mecit; Günen, Hakan; Akyıldız, Levent; Çilli, Aykut; Özlü, Tevfik; Uzaslan, Esra; Abadoğlu, Öznur; Bayram, Hasan; Çımrın, Arif Hikmet; Gemicioğlu, Bilun; Mısırlıgil, ZeynepPurpose: In order to determine the clinical and sociodemographic characteristics of newly diagnosed treatment-naive asthma and COPD patients in Turkey, a multicenter study in 2012 was initiated. We aimed to investigate the characteristics and therapies of COPD patients in the original study in more detail. Patients and Methods: This nation-wide, multicentric, non-interventional, prospective, real-life observational cohort study was conducted in 122 centers. The newly diagnosed patients were not receiving any treatment before the recruitment. Their general characteristics, the combined GOLD 2011 COPD categories and exacerbation histories were noted. The patients were followed up with 3 voluntary visits for 1 year. Their adherence to the inhaled treatment according to GOLD 2011 was evaluated during follow-up visits. Results: The study included 776 COPD patients. Their mean age was 59.4 +/- 9.1 years, and 11.9% of the patients were female. 35.1% of the patientswere in the GOLD 2011 C and D category. 12.6% are frequent exacerbators, and 52.8% had at least one comorbid condition. 71.8% overtreatment rate was detected. Their attendance rates for three follow-up visits became 55.9%, 32.9% and 18.7%, respectively. The adherence rate to the treatment was measured as 81.9%. Conclusion: Although these patients were diagnosed for the first time, the GOLD C and D categories and frequent exacerbator phenotype were found at a high rate. They were usually prescribed an overtreatment regimen. We think that newly diagnosed COPD patients should be evaluated carefully, and best effort should be made to treat these patients in accordance with the recommendations of the major COPD guidelines.Öğe Factors Affecting Control and Adherence to One Year Treatment in Elderly Asthmatics in Turkey(MOSBY-ELSEVIER, 2016) Gemicioğlu, Bilun; Bayram, Hasan; Çımrın, Arif; Abadoğlu, Öznur; Çilli, Aykut; Uzaslan, Esra; Günen, Hakan[Abstract not Available]Öğe Newly Diagnosed Asthma In The Elderly: Is It Really Different?(MOSBY-ELSEVIER, 2014) Gemicioğlu, Bilun; Abadoğlu, Öznur; Akyıldız, Levent; Bayram, Hasan; Çilli, Aykut; Çımrın, Arif; Günen, Hakan[Abstract not Available]Öğe Real life profile of asthma and chronic obstructive pulmonary disease patients in Turkey(TURKISH ASSOC TUBERCULOSIS & THORAX, 2017) Mısırlıgil, Zeynep; Cimrin, Arif; Günen, Hakan; Özlü, Tevfik; Çilli, Aykut; Akyıldız, Levent; Bayram, HasanIntroduction: Despite the presentation of similar symptoms, the airway diseases have different underlying pathophysiological processes and must be distinguished to enable the administration of appropriate treatment. In several studies the clinician-and patient-related causes of poor compliance to treatment in asthma/chronic obstructive pulmonary disease (COPD) patients have been evaluated. This study aimed to determine the clinical and sociodemographic characteristics of newly diagnosed treatment-naive asthma and COPD patients in Turkey. Materials and Methods: This national, multicentre, prospective, observational study was conducted in 122 centres. A questionnaire including items related to demographic, clinical, laboratory parameters was applied. All patients were intended to be followed-up for 12 months. Results: 1892 adult patients (1116 asthma and 776 COPD) from 122 centres were enrolled. Overall 95%,86% and 65% of intermittent, mild persistent and moderate persistent asthma patients were over-treated. Among COPD patients, the percentages of over-treated patients were 66%, 79% and 82% for those with GOLD stage A, B and C. Physicians' adherence to guidelines was appropriate in 93% of severe persistent asthma patients and 89% of GOLD stage D COPD patients. Among patients with high compliance to treatment, proportion of asthma patients with total control was 44% and that of COPD patients at GOLD stage A was 41%. In consecutive two visits, this figure increased to 52% and 63% in asthma patients and 54% and 50% in COPD patients. Conclusion: The main findings are: (a) patients are frequently over-treated and (b) patients do not adhere to visits as expected, in both asthma and COPD.
