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Öğe Clinical and surgical profile and follow up of patients with liver hydatid cyst from an endemic region(2008) Tekin A.; Kücükkartallar T.; Kartal A.; Kaynak A.; Özer Ş.; Tavli Ş.; Belviranli M.Aim: The aim of this study is to present the changes in the treatment of liver hydatid cyst during the last 20 years in our clinic according to literature data. Material and methods: Clinical, laboratory and operational findings and pre- and postoperative complications of 650 from 700 patients with liver hydatid cysts, examined and treated at Selcuk University Meram Medicine Faculty, General Surgery Department, between 1985-2005, were evaluated in two groups: 1st period (1985-1995) and 2nd period (1995-2005). Results: 436 of the cases were females (67.1%) and 214 (32.9%) males. The mean age of the females was 35 years (ranges 10-73) and of the males 46 years (ranges 12-76). Surgical treatment comprised radical and obliterative conservative techniques in the first period, while non-obliterative conservative techniques and percutaneous puncture and aspiration of the cyst, injection of scolex eliminating substance and reaspiration (PAIR) were preferred in the second period. During the follow-up (498 cases were followed for a mean period of 32 [12-72] months), recurrence occurred in 12 in the first period and in 9 in the second period, a total of 21 patients (4.21%). Conclusion: We consider that regardless of the surgical treatment used in liver hydatid cyst cases, combination with chemotherapy is the safest and most effective approach.Öğe Percutaneous cholecystostomy with locking trocar: how I do it?(2003) Vatansev C.; Belviranli M.Cholecystectomy and open cholecystostomy are associated with a high mortality rate in critically ill patients. Ultrasound-guided percutaneous cholecystostomy has a high success rate with few complications. The following method of percutaneous cholecystostomy with locking trocar (LT) under direct laparoscopic vision is seen to be an effective, safe, and practical procedure. After the abdomen is prepared from xiphisternum to symphysis pubis, the umbilicus and surrounding skin are infiltrated with 1% combined lignocaine and adrenaline. A 10-mm laparoscopy trocar is inserted via a 10-mm subumbilical incision. After a camera is inserted via the trocar, the abdomen and gallbladder are exposed. The skin of the geometric projection of fundus is infiltrated with the same solution, and a 5-mm LT is introduced via a 5-mm skin incision directed to the fundus of the gallbladder guided by the direct view of a laparoscope. When the LT has penetrated to the gallbladder, the bile and contents of the gallbladder are aspirated immediately to reduce the pressure, and the trocar is locked. The locked trocar is fixed to the abdominal wall under traction until the completion of peritonization to prevent bile leakage. The gallstones can be extracted through the trocar by a laparoscopy forceps. This technique was used for a 75-year-old woman with calculous cholecystitis and cardiopulmonary insufficiency, and her progress at this writing is good.Öğe Repeated supramaximal exercise-induced oxidative stress: Effect of ?-Alanine plus creatine supplementation(Kowsar Medical Publishing Company, 2016) Belviranli M.; Okudan N.; Revan S.; Balci S.; Gokbel H.Background: Carnosine is a dipeptide formed from the ?-alanine and histidine amino acids and found in mainly in the brain and muscle, especially fast twitch muscle. Carnosine and creatine has an antioxidant effect and carnosine accounts for about 10% of the muscle's ability to buffer the H+ ions produced by exercise. Objectives: The aim of the study was to investigate the effects of beta alanine and/or creatine supplementation on oxidant and antioxidant status during repeated Wingate tests (WTs). Patients and Methods: Forty four sedentary males participated in the study. Participants performed three 30s WTs with 2 minutes rest between exercise bouts. After the first exercise session, the subjects were assigned to one of four groups: Placebo, Creatine, Beta-alanine and Beta-alanine plus creatine. Participants ingested twice per day for 22 consecutive days, then four times per day for the following 6 days. After the supplementation period the second exercise session was applied. Blood samples were taken before and immediately after the each exercise session for the analysis of oxidative stress and antioxidant markers. Results: Malondialdehyde levels and superoxide dismutase activities were affected by neither supplementation nor exercise. During the pre-supplementation session, protein carbonyl reduced and oxidized glutathione (GSH and GSSG) levels increased immediately after the exercise. However, during the post-supplementation session GSH and GSSG levels increased in beta-alanine and beta-alanine plus creatine groups immediately after the exercise compared to pre-exercise. In addition, during the post-supplementation session total antioxidant capacity increased in beta-alanine group immediately after the exercise. Conclusions: Beta-alanine supplementation has limited antioxidant effect during the repeated WTs. © 2016, Sports Medicine Research Center.Öğe Serum levels of calcium, selenium, magnesium, phosphorus, chromium, copper and iron - their relation to zinc in rats with induced hypothyroidism(2013) Baltaci A.K.; Mogulkoc R.; Belviranli M.There is an important relation between thyroid hormones and zinc. Establishment of low zinc levels in hypothyroidism and high levels in hyperthyroidism is a significant proof of this relation. The aim of the present study was to explore changes in serum levels of some elements and their relation to zinc in rats with hypothyroidism. Thirty adult male rats of Sprague-Dawley type were divided into 3 equal groups: group 1, control; group 2, sham-hypothyroidism group supplemented with 10 mg/kg serum physiologic i.p. for 4 weeks; and group 3, hypothyroidism group supplemented with 10 mg/kg propylthiouracil i.p. for 4 weeks. Blood samples were collected from all animals by decapitation and serum calcium, phosphorus, chromium, copper, iron, magnesium, selenium and zinc levels were analyzed using an atomic emission apparatus. Group 3 had lower calcium, selenium and zinc levels, and higher chromium, copper, iron and phosphorus levels (p<0.01 all) relative to groups 1 and 2. Study parameters did not differ between groups 1 and 2. Results obtained in this study indicate that hypothyroidism leads to changes in serum levels of some elements in rats. These changes may be associated with reduced zinc levels in hypothyroidism.
