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  • Küçük Resim Yok
    Öğe
    Effect of the percentage of body fat on surgical, clinical and pathological outcomes in women with endometrial cancer
    (WILEY, 2015) Kerimoglu, Ozlem Secilmis; Pekin, Aybike; Yilmaz, Setenay Arzu; Yavas, Guler; Beyhekim, Fatma; Demirtas, Ayse Ayda; Dogan, Nasuh Utku
    AimThis study used the measure of percentage of body fat (%BF) to define obesity and evaluated the effect of percentage of %BF on clinical, surgical and pathological features in women with endometrial cancer. MethodsBetween 2011 and 2013, bioelectrical impedance analysis and body size measurements of 94 patients whose endometrial biopsy revealed endometrial cancer were obtained. Patients were divided into two groups according to body mass index (BMI) (normal, <30kg/m(2); elevated, 30kg/m(2)), and also classified by %BF (normal, <32%; elevated, 32%). ResultsThe patients' mean age was 55.010.9 years. Mean %BF and BMI were 40.8%+/- 9.8% and 32.9 +/- 7.5, respectively. Eighty-three (88%) patients were obese according to %BF; 54 (57%) were obese according to BMI. Patients with elevated %BF were more likely to have less than 50% myometrial invasion (P=0.004). Significantly more para-aortic lymph nodes were retrieved in patients with normal %BF or BMI (P<0.001, P<0.001). Patients with elevated %BF had longer operating times (P=0.043) and were more likely to have stage I disease than patients with normal %BF (P<0.001). ConclusionEndometrial cancer patients with an elevated %BF are more likely to have stage I disease and less than 50% myometrial invasion than patients with normal %BF. Defining obesity by BF may provide better estimation of obesity prevalence in patients with endometrial cancer and further understanding the relationship between BF with endometrial cancer may give more information about the effects of obesity on endometrial cancer.
  • Küçük Resim Yok
    Öğe
    Ektopik Gebelik Olgularında Tedavi Seçenekleri ve Başarı Oranlarımız
    (2014) Kerimoğlu, Özlem Seçilmiş; Kebapçılar, Ayşe Gül; Pekin, Aybike; Yılmaz, Setenay Arzu; Beyhekim, Fatma; Çelik, Çetin
    Giriş: Bu çalışmanın amacı kliniğimizde son üç yılda ektopik gebelik tanısı ile tedavi edilen hastaların tanı ve tedavi yaklaşımlarının irdelenerek tedavi başarı oranlarımızın belirlenmesidir. Gereç ve yöntem: 2010 ve 2013 tarihleri arasinda ektopik gebelik tanısı alan ve tedavi edilen toplam 77 olgu retrospektif olarak incelendi. Bulgular: Vakalarımızın yaş aralığı 20-44 yaş olup, ortalaması 29.27 4.99 olarak saptandı. Olgularımızın ektopik gebelik yerleşim yeri 74 (% 97) tubal, 1(% 1) servikal, 1(% 1) ovaryal ve 1(% 1) ise sezeryan skar hattı idi. Metotreksat tedavisine yanıt % 68.5 olarak hesaplandı. Maternal mortalite görülmedi. Sonuç: Ektopik gebelik fertiliteyi etkilemesi, mortalite ve morbiditesinin yüksek olması bakımından günümüzde hala önemini koruyan bir hastalıktır.