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Öğe Antibacterial Activity of a New Endodontic Sealer Against Enterococcus Faecalis(Canadian Dental Assoc, 2006) Bodrumlu, Emre; Semiz, MustafaAim: The purpose of this study was to test a new root canal sealer ( Epiphany) and 5 other root canal sealers ( Diaket, Endomethasone, AH 26, Sealapex, Sultan) for their antimicrobial effect on Enterococcus faecalis. Materials and Methods: The antimicrobial effect of 6 root canal sealers was tested by the agar diffusion method. The freshly mixed sealers were placed in prepared wells of agar plates inoculated with E. faecalis. All plates were incubated for 72 hours at 37 degrees C under aerobic conditions, and zones of inhibition were measured at 24, 48 and 72 hours. Results: All of the sealers caused bacterial growth inhibition. Their effectiveness, in descending order of antimicrobial activity, was as follows: Endomethasone, Sultan, Sealapex, Diaket, Epiphany and AH 26. Epiphany sealer had little effect on the tested microorganism. The effectiveness of the root canal sealers decreased marginally with greater duration of incubation. Conclusions: The Epiphany root canal sealer offered no antibacterial advantage over the other sealers tested.Öğe The antimicrobial and antifungal efficacy of tetracycline-integrated gutta-percha(Medknow Publications, 2008) Bodrumlu, Emre; Alaçam, Tayfun; Semiz, MustafaThe purpose of this study was in vitro evaluation of the antimicrobial and antifungal efficacy of commercially available gutta-percha containing tetracycline on some potential endodontic pathogens. The test microorganisms were Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Porphyromonas endodontalis, and Candida albicans. Tetracycline-integrated gutta-percha (TGP) cones, tetracycline disc, and conventional gutta-percha cones of the same size were placed on the inoculated plates. The plates were incubated at 37°C aerobically or anaerobically. Growth inhibition zones on each plate were inspected at 24, 48, and 72 h. Tetracycline disc and TGP cones inhibited all the tested bacterial strains, however the greatest antimicrobial effect was seen on S. aureus. Tetracycline disc and TGP seemed less effective on E. faecalis and P. aeruginosa. However, all tested treatments were unable to affect C. albicans. Based on the results of this study, it seems that TGP offers an antimicrobial advantage over conventional gutta-percha.Öğe Efficacy of 3 Techniques in Removing Root Canal Filling Material(CANADIAN DENTAL ASSOC, 2008) Bodrumlu, Emre; Uzun, Oezguer; Topuz, Oezguer; Semiz, MustafaObjective: Retreatment of a root canal in the case of infection requires complete removal of previous filling material. This study evaluated the efficacy of 3 techniques in removing laterally compacted Resilon/Epiphany and gutta-percha/AH Plus from straight and curved canals during retreatment. Materials and Methods: Extracted human teeth (90 maxillary anterior teeth with single, straight root canals and 90 mandibular molars with mesial canal root curvatures of 20 to 35) were divided into 6 groups each consisting of 15 straight and 15 curved root canals. Three groups were obturated using gutta-percha/AH Plus and 3 were obturated with Resilon/Epiphany. After 3 weeks storage at 37 degrees C and 100% humidity, all root canal fillings were removed using a Gates Glidden drill, a Gates Glidden drill plus chloroform or a System B device. Results: For all removal techniques, specimens obturated with gutta-percha/AH Plus showed significantly more remnants of obturation material than specimens filled with Resilon/Epiphany for both straight and curved canals (p < 0.05). Removal time was shorter for Resilon/Epiphany than gutta-percha/AH Plus filling for all techniques and for both curved and straight canals. The Gates Glidden drill and Gates Glidden drill plus chloroform removal techniques were significantly faster than the System B technique for both straight and curved canals. The Gates Glidden drill technique was best for straight canals, whereas the Gates Glidden drill plus chloroform was the best technique for curved canals when removing Resilon/Epiphany sealer. Conclusions: Removal of Resilon/Epiphany filling resulted in fewer remnants and was faster than gutta-percha/AH Plus removal using a Gates Glidden drill with or without chloroform in both straight and curved canals.