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Öğe Assessment of the effects of antihistamine drugs on mood, sleep quality, sleepiness, and dream anxiety(TAYLOR & FRANCIS LTD, 2014) Ozdemir, Pinar Guzel; Karadag, Ayse Serap; Selvi, Yavuz; Boysan, Murat; Bilgili, Serap Gunes; Aydin, Adem; Onder, SevdaObjective. There are limited comparative studies on classic and new-generation antihistamines that affect sleep quality and mood. The purpose of this study was to determine and compare the effects of classic and new-generation antihistamines on sleep quality, daytime sleepiness, dream anxiety, and mood. Methods. Ninety-two patients with chronic pruritus completed study in the dermatology outpatient clinic. Treatments with regular recommended therapeutic doses were administered. The effects of antihistaminic drugs on mood, daytime sleepiness, dream anxiety, and sleep quality were assessed on the first day and 1 month aft er. Results. Outpatients who received cetirizine and hydroxyzine treatments reported higher scores on the depression, anxiety, and fatigue sub-scales than those who received desloratadine, levocetirizine, and rupatadine. Pheniramine and rupatadine were found to be associated with daytime sleepiness and better sleep quality. UKU side effects scale scores were significantly elevated among outpatients receiving pheniramine. Classic antihistamines increased daytime sleepiness and decreased the sleep quality scores. New-generation antihistamines reduced sleep latency and dream anxiety, and increased daytime sleepiness and sleep quality. Conclusion. Both antihistamines, significantly increased daytime sleepiness and nocturnal sleep quality. Daytime sleepiness was significantly predicted by rupadatine and pheniramine treatment. Cetirizine and hydroxyzine, seem to have negative influences on mood states. Given the extensive use of antihistamines in clinical settings, these results should be more elaborately examined in further studies.Öğe Benefits of submucous resection on sleep quality, daytime and dream anxiety in patients with nasal septal deviation(SPRINGER LONDON LTD, 2013) Gulec, Tezay Cakin; Yoruk, Ozgur; Gulec, Mustafa; Selvi, Yavuz; Boysan, Murat; Oral, Elif; Yucel, AtakanThe aim of this report was to assess the frequency of poor sleep quality, daytime and dream anxiety and their response to subsequent surgical treatment for a representative group of 68 patients with nasal septum deviation. Nasal airflows and airway resistances were measured using rhinomanometry and the participants were also asked to fill in Pittsburgh Sleep Quality Index, Beck Anxiety Inventory, and Van Dream Anxiety Scale directly before the submucous resection without turbinectomy and 2 months later. Repeated measure analyses of variance models showed that patients reported significantly lower scores of poor sleep quality, daytime anxiety, and as well as dream anxiety after surgical treatment (P < 0.01). Nasal septal surgery might have beneficial effects on sleep variables in patients with deviation.Öğe Comparison of Venlafaxine Alone Versus Venlafaxine Plus Bright Light Therapy Combination for Severe Major Depressive Disorder(PHYSICIANS POSTGRADUATE PRESS, 2015) Ozdemir, Pinar Guzel; Boysan, Murat; Smolensky, Michael H.; Selvi, Yavuz; Aydin, Adem; Yilmaz, EkremObjective: Phototherapy, ie, bright light therapy, is an effective and safe treatment of major depressive disorder (MDD). It exerts rapid mood-elevating activity, similar to antidepressant medications, most likely mediated through both monoaminergic and circadian system melatonergic mechanisms. We assessed the efficiency of bright light therapy as an adjuvant treatment to antidepressant pharmacotherapy in patients with severe MDD randomized by Hamilton Depression Rating Scale (HDRS) score to either (1) 150 mg venlafaxine hydrochloride daily at 7: 00 am or (2) 150 mg venlafaxine plus 60-minute light of 7000 lux the initial week of clinical management (venlafaxine + bright light therapy) daily at 7: 00 am. Method: 50 inpatients with severe MDD at the Psychiatry Clinic of Yuzuncu Yil University Training and Education Hospital participated. The study, which was conducted from January 2013 through June 2014, entailed patients diagnosed with severe MDD based on DSM-IV-TR for the first time. Mood states were assessed by the HDRS, Profile of Mood States (POMS), and Beck Depression Inventory (BDI) before treatment and at 1, 2, 4, and 8 weeks of treatment. Results: On the basis of the HDRS score as the primary outcome variable, both strategies significantly improved depression and negative mood states already at the first treatment week (P < .001). Differences in therapeutic effects by treatment strategy were remarkable at the second and fourth weeks of clinical management (P = .018 and P = .011, respectively), with beneficial effects continuing until trial Conclusion. Those treated with venlafaxine + bright light therapy evidenced significantly lower HDRS depression scores (P < .05) as well as BDI scores (P < .05) and POMS negative mood states scores (depression-dejection, tension-anxiety, anger-hostility, fatigue-inertia, and confusion-bewilderment subscales; all P < .05) after the second week. At week 4 of the trial, 19 (76%) of the 25 venlafaxine + bright light therapy patients versus just 11 (44%) of the 25 venlafaxine patients (P < .05) attained the target goal of treatment, a HDRS score = 13, indicative of mild depression, and, although not statistically significant in our small sample study (P = .36), at week 8, 76% of venlafaxine + bright light therapy patients (n = 19) versus just 64% of the venlafaxine patients (n = 16) experienced complete remission of depression (HDRS score = 7). Conclusions: Both venlafaxine and venlafaxine + bright light therapy treatment strategies significantly reversed the depressive mood of patients with severe MDD; however, the latter induced significantly stronger and more rapid beneficial effects. Future longer-term studies with large sample sizes, nonetheless, are required to confirm and generalize these results to patients of diverse ethnicities and cultures with both severe and mild MDD. (C) Copyright 2015 Physicians Postgraduate Press, Inc.Öğe The effects of biological rhythms and sleep quality on benign paroxysmal positional vertigo and reflux symptom severity(TAYLOR & FRANCIS LTD, 2017) Celiker, Metin; Selvi, Yavuz; Ozgur, Abdulkadir; Terzi, Suat; Boysan, Murat; Polat, Hatice Beyazal; Dursun, EnginRecently, there has been increased interest in chronotypes and clinical differences between them. However, there is limited information about the potential influence of the chronotypes on clinical manifestations and symptom intensity of somatic diseases. The aim of this study is to evaluate the impact of biological rhythm differences and sleep quality on benign paroxysmal positional vertigo (BPPV) and larengo pharyngeal reflux (LPR) severity. Forty-four LPR patients, 43 BBPV patients and 42 controls were included in the study. The morningness-eveningness questionnaire was used to determine chronotypes, and the Pittsburgh Sleep Quality Index was used to assess subjective sleep quality. Both patient groups reported a significantly greater tendency to eveningness diurnal preferences compared to healthy controls. As with the circadian preferences, patients with BPPV or LPR characterized by poorer sleep quality and worse insomnia than non-patient individuals. It can be concluded that the circadian rhythm and sleep quality are related to the severity of LPR and BPPV.Öğe The Effects of Individual Biological Rhythm Differences On Sleep Quality, Daytime Sleepiness and Correlations with Dissociative Experiences(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2015) Selvi, Yavuz; Kandeğer, Ali; Boysan, Murat; Akbaba, Nursel; Uygur, Ömer F.; Sayın, Ayça A.; Tekinarslan, Emine[Abstract not Available]Öğe The effects of individual biological rhythm differences on sleep quality, daytime sleepiness, and dissociative experiences(ELSEVIER IRELAND LTD, 2017) Selvi, Yavuz; Kandeger, Ali; Boysan, Murat; Akbaba, Nursel; Sayin, Ayca A.; Tekinarslan, Emine; Koc, Basak O.Individuals who differ markedly by sleep chronotype, i.e., morning-type or evening-type also differ on a number of psychological, behavioral, and biological variables. Among several other psychological functions, dissociation may also lead to disruption and alteration of consciousness, which may facilitate dream-like experiences. Our study was aimed at an inquiry into the effects of individual biological rhythm differences on sleep quality and daytime sleepiness in conjunction with dissociative experiences. Participants were 372 undergraduate college students, completed a package of psychological instruments, including the Morningness-Eveningness Questionnaire, Dissociative Experiences Scale, Insomnia Severity Index, and Epworth Sleepiness Scale. Using logistic regression models, direct relations of pathological dissociation with sleepiness, sleep quality and circadian preferences were investigated. Poor sleep quality and sleepiness significantly contributed to the variance of dissociative symptomatology. Although there was no substantial linear association between circadian preferences and pathological dissociation, having evening-type preferences of sleep was indirectly associated with higher dissociation mediated by poor sleep quality. Poor sleep quality and daytime sleepiness seems to be significant antecedents of pathological dissociation. Sleep chronotype preferences underlie this relational pattern that chronobiological characteristics seem to influence indirectly on dissociative tendency via sleep quality.Öğe Effects of shift work on attention deficit, hyperactivity, and impulsivity, and their relationship with chronotype(TAYLOR & FRANCIS LTD, 2015) Selvi, Fatma Feray; Karakas, Sibel Asi; Boysan, Murat; Selvi, YavuzThere is growing evidence that shift-work schedules cause severe disturbances to circadian rhythms and the sleep-wakefulness cycle, and that these changes in turn lead to cognitive and behavioral problems. The objective of this study is to explore the relationships between biological rhythm differences (chronotype) and impulsive behaviors and attention-deficit hyperactivity symptoms in shift workers. Seventy-nine nurses working in the daytime and 127 nurses working on night shifts were evaluated with the Barratt Impulsiveness Scale, Adult Attention Deficit Hyperactivity Disorder Self-Report Scale (ASRS), and Morningness-Eveningness questionnaire for identifying circadian preference. It was found that shift workers had more attention deficit (p.05) and impulsivity (p.01) when compared with daytime workers. Morning-type workers reported lower hyperactivity and ASRS total scores than evening- and intermediate-type workers. The mean impulsivity score of evening-type workers was higher than both the other groups (p.05). It has been shown that attention deficit, hyperactivity, and impulsivity levels that appear as a result of working shifts might change in accordance with the individual's chronotype. It might, therefore, be desirable to evaluate an individual's chronotype to establish suitability for working shifts.Öğe Heterogenity of Sleep Quality in Relations Between Cirdadian Preferences and Depressive Symptomatology Among Major Depression Patients(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2015) Selvi, Yavuz; Uygur, Ömer F.; Boysan, Murat; Kandeğer, Ali; Sayın, Ayça A.; Akbaba, Nursel; Koç, Başak[Abstract not Available]Öğe Mood and metabolic consequences of sleep deprivation as a potential endophenotype' in bipolar disorder(ELSEVIER, 2013) Aydin, Adem; Selvi, Yavuz; Besiroglu, Lutfullah; Boysan, Murat; Atli, Abdullah; Ozdemir, Osman; Kilic, SultanIt has been commonly recognized that circadian rhythm and sleep/wake cycle are causally involved in bipolar disorder. There has been a paucity of systematic research considering the relations between sleep and mood states in bipolar disorder. The current study examines the possible influences of sleep deprivation on mood states and endocrine functions among first-degree relatives of patients with bipolar disorder and healthy controls. Blood samples were taken at two time points in the consecutive mornings at predeprivation and postdeprivation periods. Participants simultaneously completed the Profiles of Mood States at two time points after giving blood samples. Plasma T3 and TSH levels increased after total sleep deprivation in both groups. Sleep deprivation induced TSH levels were reversely associated with depression-dejection among healthy controls. A paradoxical effect was defected for only the first-degree relatives of the patients that changes in plasma cortisol levels negatively linked to depression-dejection and anger-hostility scores after total sleep deprivation. Plasma DHEA levels became correlated with vigor-activity scores after sleep deprivation among first-degree relatives of bipolar patients. On the contrary, significant associations of depression-dejection, anger-hostility, and confusion-bewilderment with the baseline plasma DHEA levels became statistically trivial in the postdeprivation period. Findings suggested that first-degree relatives of patients with bipolar disorder had completely distinct characteristics with respect to sleep deprivation induced responses in terms of associations between endocrine Functions and mood states as compared to individuals whose relatives had no psychiatric problems. Considering the relationships between endocrine functions and mood states among relatives of the patients, it appears like sleep deprivation changes the receptor sensitivity which probably plays a pivotal role on mood outcomes among the first-degree relatives of patients with bipolar disorder. (C) 2013 Elsevier B.V. All rights reserved.Öğe Psikiyatride Parlak Işık Tedavisi(2017) Özdemir, Pınar Güzel; Yılmaz, Ekrem; Selvi, Yavuz; Boysan, MuratParlak ışık tedavisi duygudurumda kalkınmaya ve buna bağlı olarak depresif belirtilerde düzelmeyeyol açan, sirkadiyen ritimde düzenleyici etkisi olan, antidepresan ilaçların etkisini artıran ve uykukalitesinde düzelmeye yol açan bir tedavi şeklidir. Parlak ışık tedavisi mevsimsel özellikli depresyondayüksek yanıt oranları nedeniyle birinci sıra tedavi seçeneği olarak kabul edilir. Ayrıca parlakışık tedavisi mevsimsel olmayan duygudurum bozuklukları, Alzheimer hastalığı, sirkadiyen ritimuyku bozuklukları, yeme bozuklukları, dikkat eksikliği hiperaktivite bozukluğu ve diğer davranışsaldurumlarda çalışılmıştır. Yan etkileri sıklıkla geçicidir ve genellikle maruziyet süresini azaltarakgiderilir. Bu yazıda parlak ışık tedavisinin etki mekanizmasını, etkinliğini, kullanım alanlarını,uygulama şeklini ve yan etkilerinin gözden geçirilmesi amaçlanmıştır.Öğe Psychometric properties of the Turkish version of the Clinician-Administered PTSD Scale for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (Turkish CAPS-5)(TAYLOR & FRANCIS LTD, 2017) Boysan, Murat; Ozdemir, Pinar Guzel; Yilmaz, Ekrem; Selvi, Yavuz; Ozdemir, Osman; Kefeli, Mehmet CelalBackground: In the subsequent revision of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5; American Psychiatric Association, 2013) symptoms of diagnostic criteria for post-traumatic stress disorder (PTSD) are defined in four clusters and the number of PTSD symptoms was expanded to 20. The Clinician-Administered PTSD Scale (CAPS) is the most widely used structured clinical interview and recognized as the golden standard in PTSD diagnosis. The final revision of the clinical interview form as the CAPS for DSM-5 (CAPS-5) was advanced in line with the recent revisions in DSM-5 with regards to the PTSD definition. The aim of this study was to examine the psychometric properties of the Turkish version of CAPS-5 in clinical samples and healthy controls. Methods: In the present study, 30 inpatients with PTSD and 30 inpatients with major depressive disorder consecutively presented to the Psychiatry Outpatient Clinic Yuzuncu Yil University Research Hospital, and 30 healthy controls were enrolled. All participants were included if only they reported an index trauma in the Life Events Checklist for DSM-5 (LEC-5) that bothered them during the past month. Subjects were administered a socio-demographic questionnaire, the Dissociative Experiences Scale (DES), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) along with the LEC-5, CAPS-5 and PTSD Checklist for DSM-5 (PCL-5). We used confirmatory factor analysis to compare a structured clinical interview (CAPS-5) and a self-report measure, the PCL-5 and to examine DSM-5 implied four-symptom clusters and several factor structures proposed in the literature to understand which model best represents the latent factor structure of PSTD symptoms. Using multivariate analysis of covariance, concurrent validity of both self-report and structured clinical interview was evaluated. Receiver operating characteristics (ROC) curve was utilized to obtain an optimal cut-off value of the PCL-5 scores in order to use in demarcating cases with non-cases. Results: Even though DSM-5 implied four-factor model adequately fit to either data collected using self-report or clinician-administered measures of PTSD, the latent structure of PTSD symptoms measured by either CAPS-5 or PCL-5 were best represented by six-factor Externalizing Behaviors model, particularly compared to seven-factor Hybrid model. In comparison to depressive and control groups, PTSD patients reported greater scores on the PCL-5, DES, BDI, and BAI and McNemar.2 values between two applications with two weeks interval were unsubstantial. Additionally, PTSD patients exhibited greater symptom endorsement on B, C, D, E, F, G symptom clusters and dissociative subtype than depressive patients and controls. Using signal detection analysis, a significant area under the curve (AUC) was calculated for the PCL-5 (AUC = 0.87 p < 0.001 asymptotic 95% Confidence Interval = 0.798-0.942). The PCL-5 had excellent diagnostic utility with 0.90 sensitivity and 0.80 specificity on a cut-off score >= 47. Conclusion: Turkish versions of the CAPS-5 and PCL-5 are demonstrated to have very good psychometric properties. Implications regarding the findings are discussed.Öğe Psychometric properties of the Turkish version of the PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (PCL-5)(TAYLOR & FRANCIS LTD, 2017) Boysan, Murat; Ozdemir, Pinar Guzel; Ozdemir, Osman; Selvi, Yavuz; Yilmaz, Ekrem; Kaya, NurayObjective: The posttraumatic stress disorder (PTSD) Checklist is one of the most widely used screening tool in assessing PTSD symptomatology. Several changes to PTSD definition were made in the recent revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). The aim of the study was to assess psychometric properties of the Turkish version of the PTSD Checklist for DSM-5 (PCL-5), the revised version conforming to the advances in DSM-5. Method: Psychiatric outpatients with PTSD (n = 29) and major depressive disorder (n = 73) and a community group (n = 360) included in the study. Respondents completed the PCL-5, Trauma Symptom Checklist-40, Life Events Checklist for DSM-5, Dissociative Experiences Scale, Beck Anxiety Inventory, Beck Depression Inventory and Posttraumatic Cognitions Inventory. Results: We found a four-factor solution best fit to the data providing support for the vast array of PTSD research. The PCL-5 demonstrated good reliability with composite reliability coefficients of re-experiencing (.79-.92), avoidance (.73-.91), negative alterations (.85-.90) and hyper-arousal (.81-.88) and temporal reliability with two-week test retest intra-correlation coefficients of .70, .64, .78, and .76, respectively. Strong associations of the total and sub-scale scores of the PCL-5 with other measures of trauma-related symptoms were indicative of construct validity of the screening tool. The current investigation suggested a cut-off score >= 47 for PTSD diagnosis, with .76 sensitivity and .69 specificity. Conclusion: The PCL-5 is a promising screening tool with sound psychometric properties.Öğe Psychometric properties of the Turkish version of the Sleep Hygiene Index in clinical and non-clinical samples(W B SAUNDERS CO-ELSEVIER INC, 2015) Ozdemir, Pinar Guzel; Boysan, Murat; Selvi, Yavuz; Yildirim, Abdullah; Yilmaz, EkremObjective: Sleep is one of the most significant of human behaviors, occupying roughly one third of human life. Sleep is a process the brain requires for proper functioning. Sleep hygiene can be described as practices to ease sleep and to avoid factors which decrease sleep quality. Inadequate sleep hygiene generally results in disturbance of daily life activities due to inability to sustain sleep quality and daytime wakefulness. Therefore, the importance of development and utilization of measures of sleep hygiene increases. The aim of the study was to assess psychometric properties of the Sleep Hygiene Index (SHI) in clinical and non-clinical Turkish samples. Method: Data were collected from 106 patients with major depression consecutively admitted to the psychiatry clinic of Yuzuncu Yil University School of Medicine and 200 were volunteers recruited from community sample who were enrolled at the university. The SHI, Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI) and Epworth Sleepiness Scale (ESS) were administered to the subjects. Factor structure of the SHI was evaluated with explanatory and multi-sample confirmatory factor analyses. Pearson product-moment correlation coefficients of the SHI with the PSQI, IST and ESS were computed. Item analyses, internal consistency coefficients and intra-class correlations between two repeated applications in both patient and healthy subjects were calculated. Results: The Sill revealed a unidimensional factor structure. Significant strong partial associations of the SHI with depression, insomnia and poor sleep quality and a modest partial association with sleepiness were detected. Cronbach's alphas for the SHI in community sample and patients with major depression were 0.70 and 0.71, respectively. Additionally, we found acceptable three-week temporal reliability in terms of intra-correlation coefficients of r = 0.62, p < 0.01 for the community sample and of r = 0.67, p < 0.01 among patients with major depression. Conclusion: The SHI revealed adequate validity and reliability to be used by researchers in Turkish sample. Current results were discussed in light of previous findings and theoretical considerations. (C) 2015 Elsevier Inc. All rights reserved.Öğe The relationship of consumers' compulsive buying behavior with biological rhythm, impulsivity, and fear of missing out(TAYLOR & FRANCIS LTD, 2019) Aydin, Duygu.; Selvi, Yavuz.; Kandeger, Ali.; Boysan, MuratIn this study, we aimed to investigate the relationship between compulsive buying (CB), biological rhythm, impulsivity, and fear of missing out (FoMO). The data in the research was collected from 493 university students using a package of psychological tools including the personal questionnaire, the Compulsive Buying Scale (CBS), Barratt Impulsiveness Scale (BIS-11), Fear of Missing Out Scale (FoMOs), Morningness-Eveningness Questionnaire (MEQ), Sleep Hygiene Index (SHI), and Depression Anxiety Stress Scale-21 (DASS-21). One-way analysis of variance was used to investigate the differences in scales scores across chronotypes, and hierarchical regression analysis to understand the relationships of compulsive buying scores with socio-demographic characteristics and scales scores. Morning-typeindividuals reported lower scores on the CBS, impulsivity, FoMOs, anxiety, and stress than evening-types or neither-types. According to the hierarchical regression analyses, compulsive buyers reported significantly greater levels of impulsivity, depression, anxiety, and fear of missing out. The results showed that evening-type individuals were more likely to compulsive buying behaviors, impulsivity, and FoMO. In conclusion, this study revealed pioneering findings in terms of CB-related factors. It also showed the relationship between consumers' compulsive buying behavior, and FoMO and the effect of circadian preferences in biological rhythms on this relationship.Öğe Relationships between coronary angiography, mood, anxiety and insomnia(ELSEVIER IRELAND LTD, 2015) Özdemir, Pınar Güzel; Selvi, Yavuz; Boysan, Murat; Özdemir, Mahmut; Akdağ, Serkan; Öztürk, FatihThe purpose of this study was to investigate and compare the anxiety, depression and insomnia levels in the pre- and post-coronary angiography in patients undergoing elective coronary angiography due to suspected coronary artery disease. This prospective cross-sectional study consisted of 120 patients consecutively underwent coronary angiogram (CAG) between January and August 2014 in Departments of Cardiology. The mean age was 57.49 (SD +/- 9.73), and 58.3% of the sample were women. The Hospital Anxiety and Depression Scale, Profile of Mood States Scale, Spielberger's State-Trait Anxiety Inventory, and Insomnia Severity Index were used. Patients were subsumed under 2 groups as normal and critical according to the presence or the absence of visually severe stenosis in at least one coronary artery. Subjects with significant stenosis had greater mean scores on depression-dejection and anger-hostility sub-scales of the POMS in the post-angiography than pre-angiography scores. We found that older age and having a physical illness significantly contributed to the risk of having significant stenosis in coronary vasculature. Subjects with severe coronary artery stenosis scored higher on depression-dejection and anger-hostility sub-scales at the post-angiography time period relative to pre-angiography scores. Trait and state anxiety levels were found to be moderate higher in both groups. (C) 2015 Elsevier Ireland Ltd. All rights reserved.Öğe The role of patient chronotypes on circadian pattern of chronic pruritus: a latent growth modeling analysis(TAYLOR & FRANCIS LTD, 2013) Bilgili, Serap Gunes; Aydin, Adem; Selvi, Yavuz; Karadag, Ayse Serap; Boysan, Murat; Onder, Sevda; Yilmaz, Hatice BurakgaziChronic pruritus is a serious medical and psychiatric disorder that can have a huge impact on a patient's quality of life. Hence, we aimed to examine whether the chronotype characteristics impact on the severity of pruritus throughout the day. In our study we included 83 idiopathic chronic pruritus patients who did not have any underlying dermatological, systemic, or metabolic diseases. We examined the change in the severity of itching symptoms throughout 24 h at four time points. The latent growth modeling approach was used to assess the significance of the chronotype effect on symptom severity after controlling for age, gender, and depression. The patients with morning chronotype characteristics reported more severe itching symptoms later in the day, while the patients with evening chronotype characteristics complained of more severe itching earlier in the day. These findings suggest that chronobiological factors might play a deterministic role on the symptom severity.Öğe Validation of the turkish version of the obsessive-compulsive inventory-revised (ocı-r) in clinical and non-clinical samples(2014) Aydın, Adem; Boysan, Murat; Kalafat, Temel; Selvi, Yavuz; Beşiroğlu, Lütfullah; Kagan, MücahitGiriş: Obsesif-Kompulsif Envanteri-Revize (OKE-R) varolan ölçme araçlarındaki sorunların üstesinden gelebilmek amacıyla geliştirilmiş yaygın olarak kullanılan bir öz değerlendirme aracıdır. Bu çalışmada, Obsesif-Kompulsif Envanterinin revize edilmiş formunun Türk örneklemindeki psikometrik özelliklerinin değerlendirilmesi amaçlanmıştır. Yöntem: Obsesif-Kompulsif Envanteri-Revizenin Türkçe formunun psikometrik özellikleri klinik örneklemlerde (obsesif-kompulsif bozukluk tanısı alan hastalarda n44 ve major depresyon tanısı alan hastalarda n44) ve klinik olmayan öğrenci örnekleminde (n287) ele alınmıştır. Bulgular: Doğrulayıcı faktör analizi sonucunda orijinal altı faktörlü yapının Türk örnekleminde geçerli olduğu bulunmuştur. Ölçeğin tümü ve alt ölçekler için orta düzeyden yükseğe doğru değişen düzeylerde iç tutarlılık, birlikte geçerlik ve test tekrar test geçerliği değerleri elde edilmiştir. İstifleme alt ölçeği için obsesif kompulsif grupta çok düşük Cronbach alfa değeri elde edilmiştir. Nötürleştirme alt ölçeği dışında toplam puanların ve alt ölçeklerin genel olarak obsesif kompulsif bozukluğu olan hastaları sağlıklı kontrollerden ve major depresyon hastalarından başarıyla ayırt edebildiği görülmüştür. Sonuç: Obsesif-Kompulsif Envanteri-Revizenin Türkçe formu için yeterli psikometrik özellikler saptanmamıştır. 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