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    A case of primary ovarian lymphoma in a child with high levels of CA125 and CA19-9
    (LIPPINCOTT WILLIAMS & WILKINS, 2005) Koksal, Y; Caliskan, U; Ucar, C; Reisli, I
    Primary ovarian lymphoma is extremely rare in children. The authors report a case of primary ovarian lymphoma in a child with high levels of CA125 and CA19-9. To their knowledge, this is the first such case to be reported in the literature.
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    Comparison of iron load of the liver and gum of patients with thalassemia major.
    (AMER SOC HEMATOLOGY, 2005) Caliskan, U; Canatan, D; Ciris, M; Bozkurt, Y; Caglayan, G; Koran, M; Kosaci, S
    [Abstract not Available]
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    Diminished platelet aggregation in patients with iron deficiency anemia
    (LIPPINCOTT WILLIAMS & WILKINS, 1999) Caliskan, U; Oner, AF; Kabakus, N; Koc, H
    To evaluate platelet function in iron deficiency anemia, using impedance (in whole blood) and optic tin platelet-rich plasma methods, platelet aggregation analyses were performed in 42 children with iron deficiency anemia at the time of diagnosis and after iron therapy. Collagen-induced platelet aggregation was decreased in patients before therapy compared to after therapy and control levels as indicated by the two methods while adenosine diphosphate (ADP)-induced platelet aggregation was decreased only by the whole blood method. Platelet aggregation with epinephrine, performed only by the optic method, was not altered in patients with iron deficiency anemia. Platelet counts were found to be increased in patients with iron deficiency anemia, and decreased with therapy. These results indicate that some platelet functions are decreased in patients with iron deficiency anemia. These decreased functions may be compensated by increased platelet numbers.
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    Galactorrhea-associated granulosa cell tumor in a child
    (TAYLOR & FRANCIS INC, 2004) Koksal, Y; Reisli, I; Gunel, E; Caliskan, U; Bulun, A; Kale, G
    Granulosa cell tumor of the ovary is a rare form of ovarian cancer in children. An 11-year-old girl was admitted with complaints of galactorrhea and abdominal mass. Abdomino-pelvic ultrasound and computed tomography revealed an ovarian tumor. Her prolactine and estradiol levels were increased but luteinizing hormone and follicle-stimulating hormone were decreased. An exploratory laparotomy revealed a giant solid mass, which was completely removed and determined as juvenile granulosa cell tumor. The clinical, hormonal, and radiological findings and the therapy of galactorrhea associated with granulosa cell tumor in a child are discussed. To our knowledge, this is first time it has been described in childhood.
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    Successful treatment of acute lymphoblastic leukemia with L-asparaginase-induced intracranial hemorrhage to activated recombinant factor VIIA in a child
    (TAYLOR & FRANCIS INC, 2006) Ucar, C; Caliskan, U
    L-Asparaginase, a major component of therapy in children with acute lymphoblastic leukemia, has been shown to induce coagulopathy by inhibiting synthesis of clot-forming and clot- inhibitory proteins. The authors report the successful use of recombinant factor VIIa in a 15-year-old girl with acute lymphoblastic leukemia who had L-asparaginase-induced intracranial hemorrhage. The present case is the first to demonstrate use of rFVIIa in L-asparaginase-induced intracranial hemorrhage in a child with acute lymphoblastic leukemia.