Yazar "Dinç, Saliha" seçeneğine göre listele
Listeleniyor 1 - 6 / 6
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Biocompatible yogurt carbon dots: evaluation of utilization for medical applications(SPRINGER, 2017) Dinç, Saliha; Kara, Meryem; Kars, Meltem Demirel; Aykul, Fatmanur; Çiçekci, Hacer; Akkuş, MehmetIn this study, carbon dots (CDs) were produced from yogurt, a fermented milk product, via microwave-assisted process (800 W) in 30 min without using any additional chemical agents. Yogurt CDs had outstanding nitrogen and oxygen ratios. These dots were monodisperse and about 2 nm sized. The toxicological assessments of yogurt carbon dots in human cancer cells and normal epithelial cells and their fluorescence imaging in living cell system were carried out. Yogurt carbon dots had intense fluorescent signal under confocal microscopy and good fluorescence stability in living cell system. The resulting yogurt carbon dots exhibited high biocompatibility up to 7.1 mg/mL CD concentration which may find utilization in medical applications such as cellular tracking, imaging and drug delivery. Yogurt carbon dots have potential to be good diagnostic agents to visualize cancer cells which may be developed as a therapeutic carrier.Öğe Ground Urfa isot peppers with high content of bioactive compounds and antioxidant activity(AGRIMEDIA GMBH, 2015) Kara, Meryem; Dinç, Saliha; Kahraman, Selma; Karıpçin, M. Zeki; Alp, İrem; Çiçekci, HacerUrfa isot pepper is one of the most important spices in the diet of Turkish people; particularly of those in the Sanliurfa region. This is the first study reporting the bioactive compounds (beta-carotene, lycopene, ascorbic acid, phenolic compounds, capsaicin) and antioxidant activity of ground Urfa isot peppers produced both at homestads and factories. Factory-made red-blackish isot pepper showed the highest DPPH radical-scavenging activity, followed by homemade red-blackish isot pepper and homemade red isot pepper. FRAP values of all Urfa isot peppers were statistically in the same group. Homemade red isot pepper had the highest total phenolic content, lycopene and beta-carotene. The capsaicin content of ground Urfa isot peppers varied from 0.15-1.2 mg/g of pepper. The homemade red-blackish ground pepper had the highest ascorbic acid level. Phenolics of peppers were remarkable and higher than those reported in the literature. With their high number of phenolic constituents, as well as other bioactive compounds, ground Urfa isot peppers can be considered an important nutritional and functional food resource.Öğe High temperature-tolerant tomato lines: bioactive compounds(SPRINGER INTERNATIONAL PUBLISHING AG, 2016) Karıpçin, M. Zeki; Dinç, Saliha; Kara, Meryem; Kahraman, Selma; Alp, İrem; Çiçekci, HacerHigh global temperatures will be a great challenge for agricultural production in the near future. Therefore, adaptation of agricultural crops to the high temperatures or development of new heat-tolerant crops with known bioactive compounds is an important strategy for nutritional health and crop improvement programs. In this context, the bioactive compounds of newly developed high temperature-tolerant tomato lines were investigated in terms of lycopene, beta-carotene, ascorbic acid and phenolic compounds to assist breeders for the selection of high temperature tolerant tomato varieties with high nutritional quality. Nineteen tomato lines, including control varieties from the "Turkey F1 Hybrid vegetable variety and quality line development" project and the GAP Agricultural Research Institute, were selected for the investigation. Line 11 was superior in lycopene and beta-carotene content, while line 18 was superior in ascorbic acid content as compared to control varieties Cansun F1 and Alsancak RN F1. Urfa 2012 and line 28 were found to have the highest numbers of phenolic compounds. Chlorogenic acid, naringenin, trans-ferulic acid and rutin were key phenolic compounds detected in each of the tomato lines. These newly released tomato lines can be used as value-added germplasm or parent sources to develop new heat-tolerant cultivars in breeding programs or as commercial cultivars for their superior functional qualities.Öğe Kestane balından sentezlenen karbon noktaların tetrasiklin analizinde kullanılabilirliğinin araştırılması(2017) Dinç, SalihaDünya için bir tehdit olan antibiyotik direncinin önüne geçme yollarından birisi de gıdalarda bulunan antibiyotik kalıntılarını önlemektir. Ülkemizde antibiyotik kalıntıları et, süt, bal, yumurta gibi hayvansal gıdalarda bulunmaktadır. Antibiyotik kalıntılarının hızlı, basit ve ucuz yöntemlerle tespiti gıdalarda ki antibiyotik kalıntılarını izlemeyi kolaylaştıracaktır. Karbon noktalar 10 nm'den küçük nanopartiküller olup analitik çalışmalarda yararlanılmaktadır. Floresans özellikleri, suda çözünür olmaları ve toksik olmamaları karbon noktaların üstün özelliklerinden bazılarıdır. Bu çalışmada balda en çok rastlanan tetrasiklinin hızlı tayini için karbon noktalar kullanılmıştır. Karbon noktalar, kestane balından herhangi bir kimyasal kullanılmadan mikrodalga yöntemi ile sentezlenmiştir. UV ışık altında mavi floresans veren karbon noktaların emisyon şiddetindeki azalma (sönümleme) esas alınarak tetrasiklin analizi yapılmıştır. Artan tetrasiklin konsantrasyonlarına karşı artan sönümleme miktarları grafiğe geçirilerek kalibrasyon doğrusu elde edilmiştir. Korelasyon katsayısı (R2) 0.99 olarak hesaplanmıştır Tetrasiklin analizi başarı ile yapılmış ancak geliştirilen yöntemin gıda numunelerindeki uygulamasının yapılması gerekmektedir. Anathar Kelimeler: Karbon noktalar, Tetrasiklin, Kestane Balı, Antibiyotik kalıntısı, NanoteknolojiÖğe Promising Strain of Acinetobacter from Soil for Utilization of Gluconic Acid Production(2017) Dinç, Saliha; Kara, Meryem; Öğüt, Mehmet; Er, Fatih; Çiçekçi, HacerGluconic acid, a food additive, is used in many foods to control acidity or binds metals such as calcium, iron. Acinetobacter sp. WR326, newly isolated from soil possesses high phosphate solubilizing activity and do not require pyrroloquinoline quinone (PQQ) for glucose dehydrogenase (GDH) activity as cofactor In this study the gluconic acid production potential of this bacterium was investigated. Firstly, Acinetobacter sp. WR326 was incubated in tricalcium phosphate medium (TCP) with varying glucose concentrations (100, 250, 500 mM), at a temperature of 30C for 5 days (120 hours). The highest gluconic acid yield (59%) was found at a glucose concentration of 100 mM. Then three different levels of gluconic acid addition to the medium (50, 100, 200 mM) were tested. When Acinetobacter sp. WR326 strain was cultivated with a 100 mM glucose and 100 mM gluconic acid the yield increased to 95.27%. In any trials 2 -keto D-gluconic acid, causes problems in processing and purification of the gluconic acid, was not detected in the medium. As a conclusion, Acinetobacter sp. WR326 may be considered novel potential bacterial strain for gluconic acid production.Öğe THE ROOTSTOCK EFFECTS ON AGRONOMIC AND BIOCHEMICAL QUALITY PROPERTIES OF MELON UNDER WATER STRESS(PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2018) Dinç, Saliha; Kara, Meryem; Karipcin, M. Zeki; Sarı, Nebahat; Can, Zehra; Çiçekci, Hacer; Akkuş, MehmetIn this study Edali F1 and Balhan Fl melons (Cucumis melo L.) grafted onto different rootstocks (TZ 148 and Jumbo) under water stress conditions (W1-100%, W2-50%, W3-25%). FRAP (Ferric reducing antioxidant power) values increased with the use of TZ 148 and Jumbo rootstocks. At water stress, grafting generally increased ascorbic acid values. Maximum beta-carotene amount was stated for Balhan Fl with W3 level and the beta-carotene values of Balhan/TZ148 melons increased with water stress. p-hydroxybenzoic acid was the compound with the highest quantity among the tested phenolic compounds. Citric, maleic, fumaric and formic acid quantities increased with enhancement of water deficiency whereas tartaric, succinic and acetic acid decreased. Fructose and saccharose quantity decreased as the amount of water given to plant decreased but glucose level was not affected. Consequently, grafting of melons onto favorable rootstocks seems to enhance the amount of health related compounds under water stress conditions.
