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Öğe Biomechanical evaluation of different fixation systems after Le Fort I osteotomy in polyurethane models of unilateral clefts(CHURCHILL LIVINGSTONE, 2016) Esen, Alparslan; Isik, Kubilay; Saglam, Haci; Ozdemir, Yusuf Bugra; Dolanmaz, DoganWe compared the stability of three different titanium plate-and-screw fixation systems after Le Fort I osteotomy in polyurethane models of unilateral clefts. Thirty-six models were divided into 3 groups. In the first group, we adapted standard Plates 1 mm thick with 2.0 mm screws and placed them bilaterally on the zygomatic buttress and the piriform rim. In the second group, we did the same and added Plates 0.6 mm thick with 1.6 mm screws between the standard 2 mm miniplates on both sides. In the last group, we placed Plates 1.4 mm thick with 2.0 mm screws bilaterally on the maxillary zygomatic buttress and piriform rim. Each group was tested in the inferosuperior (IS) and anteroposterior (AP) directions with a servo-hydraulic testing unit. In the IS direction, displacement values were not significantly different up to 80 N, but between 80 and 210 N, those in the 2 x 1.4 mm group were better. In the AP direction, displacement values were not significantly different up to 40 N, but between 40 and 180 N, they were better in the standard with 1.6 x 0.6 mm group and the 2 x 1.4 mm group. When normal biting forces (90- 260 N) in the postoperative period are considered, the greatest resistance to occlusal loads was seen in the 2 x 1.4 mm group. In the others, the biomechanical properties were better in the AP direction. (C) 2016 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.Öğe Biomechanical evaluation of malleable noncompression miniplates in mandibular angle fractures: an experimental study(CHURCHILL LIVINGSTONE, 2012) Esen, Alparslan; Dolanmaz, Dogan; Tuz, Hakan HifziThe purpose of this experimental study was to test the reliability of a single malleable titanium miniplate using Champy's method of fixing fractures of the mandibular angle. Eighteen sheep hemimandibles were used to evaluate 2 plating techniques. The groups were tested with either a single non-compression titanium miniplate or a single malleable titanium miniplate. A cantilever bending biomechanical test model was used for the samples. Each group was tested with vertical forces using a servohydraulic testing unit. The displacement values in each group at each 10 N stage up to 90 N were compared using 2-way analysis of variance (ANOVA). The displacement values for the 2 groups differed significantly (p < 0.01). The variance analyses showed that the biomechanical behaviour of a single non-compression miniplate was better than that of a single malleable miniplate. The non-compression miniplate fixed by screws had greater resistance to occlusal loads than the malleable plate fixed by screws, and the malleable plate alone was not sufficient to withstand the early postoperative bite force. (C) 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.Öğe Comparison of stability of 2.0 mm standard and 2.0 mm locking miniplate/screws for the fixation of sagittal split ramus osteotomy on sheep mandibles(CHURCHILL LIVINGSTONE, 2011) Oguz, Yener; Saglam, Haci; Dolanmaz, Dogan; Uckan, SinaTen unembalmed adult sheep mandibles were used. The mandibles were sectioned in the midline, followed by sagittal split ramus osteotomies to obtain 20 hemimandibles. Each distal segment was advanced 5 mm on each hemimandible. Ten of the specimens were fixed with 4-hole extended 2.0 mm titanium miniplates and screws and the other 10 were fixed with 4-hole extended 2.0 min locking miniplates/screws. Each fixed specimen was mounted on a servo-hydraulic testing unit with the fixation device, and was tested to a range of forces of 0-140N. The displacement values (mm) under 20, 60, 120, and 140N were compared with the help of the Mann Whitney U-test, and there were no significant differences between them at any force tested. Locking miniplate/screws and standard miniplate/screws showed similar displacement values at the range of forces tested. (C) 2010 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.Öğe Comparison of two different approches to the pterygomaxillary junction in Le Fort I osteotomy(MOSBY-ELSEVIER, 2008) Dolanmaz, Dogan; Esen, Alparslan; Emlik, Dilek; Candirli, Celal; Kalayci, Abdullah; Cicekcibasi, AynurObjective. The purpose of this study was to compare the damage before and after down fracture in Le Fort I osteotomies performed with and without the separation of pterygomaxillary junction using curved osteotomes in a cadaver model. Study design. The study sample comprised 6 cadavers aged between 55 and 70 years (mean age: 63.8 years). Three cadavers were partially edentulous, 2 cadavers still maintained a full complement of teeth and 1 cadaver was edentulous. Le Fort I osteotomy was performed on all cadavers. Pterygomaxillary osteotomies were only performed on the right sides whereas the left sides were left intact. Subsequently, the maxilla was mobilized by applying digital pressure on the anterior maxillary segment. Computed tomography scans of each specimen were obtained before surgery, after surgery-before down fracture and after down fracture to document secondary fractures. Results. Before the down fracture, secondary fractures were found in only 1 specimen (right side), whereas after the down fracture, secondary fractures were found in 5 specimens by CT. After the down fracture, the rate of occurrence of secondary fractures was 62% in the right side and 38% in the left side. Conclusion. With respect to the results of the present study, the use of osteotomes for pterygomaxillary dysjunction increases the incidence of fractures in maxillary osteotomy. However, the occurrence of almost all fractures subsequent to down fracture suggests the presence of possible bony splits that could not be diagnosed by radiographic examination immediately after maxillary osteotomy may have become apparent or transformed into fractures following down fracture.Öğe Distracted mandible does not reach the same strength as normal mandible in rabbits(ELSEVIER SCIENCE INC, 2012) Bulut, Turker; Durmus, Ercan; Mihmanli, Ahmet; Dolanmaz, Dogan; Kalayci, Abdullah; Saglam, HaciObjective. The aim of this study was to determine the resistance and fracture strength values of the bone with the use of biomechanical tests in different consolidation periods of mandibular distraction osteogenesis. Study Design. In this study, 21 mature male New Zeland rabbits were used. After distraction, rabbits were separated into 3 groups to experience 4, 8, and 12 weeks' consolidation periods. Nonoperated hemimandibles of 6 rabbits were used as a control group. After 5 days' latency period, 0.5-mm distraction was applied twice a day, i.e., 1 mm/d lengthening. After the 5-mm lengthening application, we left the animals for 1, 2, or 3 months of consolidation period. Bending stress and strength values of the bone at fracture point were measured with the use of a 3-point bending test. Results. There were significant differences between the control and 3 study groups regarding bending stress and strength values. In addition, each study group was significantly different from each other. Conclusions. Bending stress and fracture strength of the bone may not reach that of normal bone after completion of 3 months' consolidation. It should be considered to keep in place extraoral appliances or comfortable intraoral distractors for a long period. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114(suppl 5): S140-S145)Öğe Effect of 2 flap designs on postoperative pain and swelling after impacted third molar surgery(ELSEVIER SCIENCE INC, 2013) Dolanmaz, Dogan; Esen, Alparslan; Isik, Kubilay; Candirli, CelalObjective. The aim of this study was to evaluate 2 flap designs (envelope and modified triangular flap) for postoperative pain and swelling after mandibular impacted third molar surgery. Study Design. Thirty patients who had symmetric bilateral fully impacted mandibular third molars were selected. Left teeth were approached with an envelope flap, and right teeth were removed using a modified triangular flap. Postoperative pain and swelling were evaluated until the seventh day by using 2 verbal rating scales. Results. Statistical analyses showed that there were no significant differences between the 2 incision techniques regarding postoperative pain and swelling (P > .05). Conclusions. There is no significant difference between the envelope and modified triangular flap regarding postoperative pain and swelling after impacted third molar surgery.Öğe The effects of osteoformin on mineralisation and quality of newly formed bone during mandibular distraction osteogenesis in rabbits(MOSBY-ELSEVIER, 2009) Pampu, A. Alper; Ozkaynak, Ozkan; Senel, Figen Cizmeci; Cankaya, Mustafa; Dolanmaz, Dogan; Ersoz, Safak; Avunduk, Mustafa CihatObjective. The aim of this experimental study was to evaluate the effects of osteoformin on mineralization and quality of newly formed bone during distraction osteogenesis in rabbits. Study design. Distraction rate was as 1 mm/day for 5 days. In the experimental group, 100 mu g/kg osteoformin in 100 mu L/kg phosphate-buffered saline (PBS) was injected into the distraction area at day 1 and day 7 after surgery. In the control group, only 100 mu L/kg PBS was injected on the same days. On day 42, the animals were killed. Results. Bone mineral density and bone mineral content values increased significantly in the experimental group (P < .05). Newly formed bone areas, number of vessels and osteoblasts were significantly greater in experimental group (P < .05). The number of fibroblasts were also greater, but it was not significant statistically (P < .05). The number of osteoclasts was significantly lower in experimental group (P < .05). Conclusion. The results of this study show that osteoformin improves healing of regenerate in distraction osteogenesis in rabbits. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 833-837)Öğe Effects of Recombinant Human Erythropoietin on Mandibular Distraction Osteogenesis(W B SAUNDERS CO-ELSEVIER INC, 2009) Mihmanli, Ahmet; Dolanmaz, Dogan; Avunduk, Mustafa C.; Erdemli, EsraPurpose: To evaluate the effects of subcutaneous administration of recombinant human erythropoietin (rHuEPO) oil regeneration formation and quality during mandibular distraction osteogenesis. Materials and Methods: Sixteen adult male New Zealand rabbits were Used ill this study Ethical approval was obtained front the Animal Research Institute of Selcuk University, Konya, Turkey Subjects were randomly divided into 2 groups Distraction osteogenesis (DO) was performed witha Custom-made distractor on the left mandibles of rabbits. In the experimental group, 4 doses of 150 IU/kg rHuEPO wet-administered at 48-hour intervals. The first close was given immediately after surgery. Control subjects received 0 5 mL/kg isotonic solution in the same manner After 2 clays of latency, mandibles were distracted I mm/day at 12-hour intervals for 5 clays. A 5-mm lengthening was achieved. All animals were sacrificed after 30 days of consolidation Afterward, samples were prepared for histomorphometric evaluation of newly formed bone area. Results: The number of osteoblasts and blood vessels was significantly higher, whereas the number of osteoclasts was significantly lower, ill the experimental group than in the control group (P < 05) In the experimental group. the area of new bone formation was greater than in the control group (P < .05). Moreover. fibroblast and collagen numbers per Unit area were higher in the experimental group However, this finding was not statistically significant (P > 05) Conclusion: The subcutaneous administration of rHuEPO improves the rate and quality of bone-healing during distraction osteogenesis. However, the short-term favorable effects of rHuEPO in tills study should be extended with long-term investigations before clinical application. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67-2337-2343, 2009Öğe Eruption of an impacted canine in an adenomatid odontogenic tumor treated with combined orthodontic and surgical therapy(MOSBY-ELSEVIER, 2016) Erdur, Emire Aybuke; Ileri, Zehra; Ugurluoglu, Ceyhan; Cakir, Mustafa; Dolanmaz, DoganAn adenomatoid odontogenic tumor is an uncommon asymptomatic lesion that is often misdiagnosed as a dentigerous cyst. It originates from the odontogenic epithelium. Enucleation and curettage is the usual treatment of choice. Marsupialization may be attempted instead of extraction of the impacted tooth, since it provides an opportunity for tooth eruption. This case report is the first to report on the eruption of an impacted canine in an adenomatoid odontogenic tumor treated with combined orthodontics and marsupialization. The impacted canine erupted uneventfully, with no evidence of recurrence 3 years after the treatment.Öğe Evaluation of strain values of critical anatomic regions for two different pterygomaxillary approaches in Le Fort I osteotomy: An experimental study(MEDICINA ORAL S L, 2017) Ozdemir, Yusuf-Bugra; Dolanmaz, Dogan; Esen, Alparslan; Terzioglu, Hakan; Saglam, HaciBackground: The purpose of this experimental study was to measure stresses both on the pterygoid plates and the skull base following two different pterygomaxillary approaches in Le Fort I osteotomy. Material and Methods: The prepared skull models were randomly divided into 2 groups of 7. In the first group (A), the pterygomaxillary area was left intact. In the second group (B), pterygomaxillary separation was performed with a fine bur. The stresses were measured by using strain gauges. These strain gauges were attached to 6 different anatomical sites. The skull models were mounted on a servo-hydraulic testing unit. Each model was then subjected to a continuous linear tension until a plastic deformation was seen. Results: The statistical analyses showed that there were no significant differences (p>.05) between the 2 groups regarding the strain values. Moreover, no statistical differences (p>.05) were found between the two groups in terms of maximum applied forces. Conclusions: Considering the clinical conditions, the present study shows that when Le Fort I osteotomy performed without pterygomaxillary separation, there is no significant stress on the skull base during the downfracture. Moreover, it is considered that there is no need for an excessive force applied to perform downfracture in Le Fort osteotomies without pterygomaxillary separation.Öğe Histological evaluation of effectiveness of platelet-rich fibrin on healing of sinus membrane perforations: A preclinical animal study(CHURCHILL LIVINGSTONE, 2017) Aricioglu, Ceyhun; Dolanmaz, Dogan; Esen, Alparslan; Isik, Kubilay; Avunduk, Mustafa CihatThe aim of this study was to evaluate the effectiveness of platelet-rich fibrin (PRF) in repairing of Schneiderian membrane perforations in rabbit maxillary sinus. A total of 42 female New Zealand rabbits were randomly divided into two groups. Symmetrical bony defects were created 1 cm in diameter and the sinus membranes were exposed. The Schneiderian membranes were elevated in both sinuses and each membrane was perforated with a 1 cm incision. No treatment was applied to the right perforations in both groups. Left-sided perforations were closed with collagen membrane in the first group and PRF membrane in the other group. Seven animals randomly selected from each group were sacrificed at weeks 1, 2 and 4 in order to be able to examine the amounts of lymphocytes, fibroblasts, veins, and collagen fibers in the area where the membranes were applied. Histological analyses showed that there were no statistically significant differences between the collagen membrane and the PRF membrane in the healing of sinus perforation area. PRF may be considered as an alternative application to collagen membrane in sinus membrane perforations. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.Öğe Histomorphometric evaluation of the effects of zoledronic acid on mandibular distraction osteogenesis in rabbits(W B SAUNDERS CO-ELSEVIER INC, 2008) Pampu, A. Alper; Dolanmaz, Dogan; Tuez, Hakan H.; Avunduk, M. Cihat; Kisnisci, Reha S.Purpose: To assess the effect of systemic administration of zoledronic acid (ZA) on mineralization of newly formed bone and to determine strain-related osteoporosis on surrounding bone during lengthening of immature rabbit mandible. Materials and Methods: Eighteen New Zealand white rabbits were divided randomly into 2 groups, and bone lengthening was carried out in the left portion of the mandible through distraction osteogenesis with a rate of 0.5 mm every 12 hours for 5 days. The experimental group was administered 0.1 mg/kg ZA intravenously. The control group was given saline infusion only during operation. All animals were sacrificed at the end of the 28-day consolidation period. The mandibles of all animals were removed and regenerate was evaluated. Osteoblasts, osteoclasts, collagen fibers, and fibroblasts were marked within 0.1-mm(2) area and newly formed bone area was measured within 0.5-mm(2) area. All data were analyzed using Mann-VAiitney U test. Results: Although irregular bone destruction spots were seen in the control group, the experimental group showed regular ossification areas and significant difference between osteoblast and osteoclast numbers (P < .05). In the regenerate zone, there was considerable difference between the 2 groups in terms of osteoblast, osteoclast, and collagen amounts (P < .05). Additionally, newly formed bone areas and fibroblast count were higher in experimental group. Conclusions: The results of this study showed that ZA had positive effects on the new bone formation, which may potentially shorten the consolidation period. (c) 2008 American Association of Oral and Maxillofacial Surgeons.Öğe Immediate mechanical stability of sagittal split ramus osteotomy fixed with resorbable compared with titanium bicortical screws in mandibles of sheep(CHURCHILL LIVINGSTONE, 2006) Cilasun, Ulkem; Uckan, Sina; Dolanmaz, Dogan; Saglam, HaciTen fresh mandibles from adult sheep were stripped of all soft tissues and sectioned in the midline. We did sagittal split osteotomies and 5 mm advancement on all the 20 hemimandibles. Ten hemimandibles were fixed with three 2.0 mm x 13 mm titanium bicortical screws, and the other 10 were fixed with three 2.0 mm x 13 MM poly-L-lactic acid/polyglycolic acid (PLLA/PGA) bicortical screws in an inverted L pattern. All the hemimandibles were then mounted in a servohydraulic testing unit and tested to permanent deformation. Maximum forces that the mandibles resisted before breaking, maximum displacements, and the displacement values under 20, 60, 120, and 150N were compared using the Mann-Whitney U-test. There were no significant differences in stability between the bones fixed with titanium and those fixed with resorbable screws. (C) 2005 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.Öğe Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature(SPRINGER HEIDELBERG, 2016) Dolanmaz, Dogan; Esen, Alparslan; Mihmanli, Ahmet; Isik, KubilayWe report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws. Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks. Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage. We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.Öğe Non-sendromik dudak damak yarığı hastalarında multidisipliner tedavi: 2 vaka raporu(2018) Ozel, Gulsum Sayın; Inan, Ozgür; Dolanmaz, Dogan; Karaman, Ali IhyaAmaç: Bu vaka raporunda 2 non-sendromik dudak damak yarıklı vakanın farklı yaklaşımlarla protetik tedavisinin değerlendirilmesi amaçlanmaktadır. Vaka Raporu: 15 yaşında tek taraflı dudak damak yarıklı erkek hasta ve 25 yaşında çift taraflı dudak damak yarıklı kadın hastalarımız kliniğimize estetik ve fonksiyon kaybından dolayı başvurmuşlardır. Ortodontik, cerrahi ve prostodontik yaklaşımlarla hastalara uygulanmıştır. Her iki vakada da sabit protetik restorasyonlar protokolleri uygulanan hastalarımızda herhangi bir komplikasyon gözlemlenmemiştir. Tedaviler yüksek hayat kalitesi ve memnuniyet sağlamıştır. Sonuçlar: Dudak damak yarıklı hastalarda; konuşma, maxillofacial büyümenin normal seyrinde devamı, fiziksel görünüşün arttırılması ve psikolojik durumun düzeltilmesi için multidisipliner yaklaşım gereklidir. zamanlamaları değerlendirilmelidirÖğe A Preferable Technique for Protecting the Inferior Alveolar Nerve: Coronectomy(W B SAUNDERS CO-ELSEVIER INC, 2009) Dolanmaz, Dogan; Yidirim, Gusun; Isik, Kubilay; Kucuk, Korban; Ozturk, AdnanPurpose: The aim of this study was to evaluate the effectiveness of coronectomy for teeth whose root apices are very close to the inferior alveolar canal. Patients and Methods: The 43 patients of this study needed removal of their lower third molar, whose root apices were very close to the inferior alveolar canal. These patients underwent 47 coronectomies. Results: The mean follow-tip period was 9.3 months (range, 1 to 48 months). The mean total amount of root movement was 3.4 mm at 6 months, 3.8 mm at 12 months, and 4.0 mm at 24 months. Conclusions: The technique of coronectomy is defined as removing the crown of a tooth but leaving the roots untouched, so that the possibility of nerve damage is reduced. Coronectomy is a preferable technique for patients who run a risk of injury to the inferior alveolar nerve during third molar surgery. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67:1234-1238, 2009Öğe Rapid canine distalization through segmental alveolar distraction osteogenesis(E H ANGLE EDUCATION RESEARCH FOUNDATION, INC, 2007) Sukurica, Yusuf; Karaman, Ali; Gurel, Hakan Gurcan; Dolanmaz, DoganObjective: The objectives of this study were to achieve rapid canine distalization by segmental alveolar distraction method in first premolar extraction cases, to examine the changes in the periodontal tissues surrounding canines, to evaluate the displacement of the canine and first molar teeth, to assess the effects of the procedure on the pulpal vitality of the canines, and to determine the amount of root resorption in retracted canines. Materials and Methods: The sample of the study consisted of 20 teeth in eight patients (four females and four males, mean age 18.5 years). Pre- and posttreatment dental casts, panoramic radiographs, and standard periapical radiographs were taken from all patients. An electrical vitality test was applied before and after the distraction procedure and during the follow-up period (6 months after the completion of the procedure). In addition, six periodontal indices were used to examine the health of the periodontal tissues. Results: The distraction procedure was completed in 12 to 28 days (mean 14.65 +/- 3.49). The anchorage loss ranged from 0 to 3 mm (mean 1.2 +/- 0.83). The distal displacement of the canines ranged from 3 to 8 mm (mean 5.35 +/- 1.22). The canines showed a mean of 9.1 degrees distal tipping, whereas there was no statistically significant change in the axial inclinations of first molars after distraction. Conclusion: We believe that rapid canine distalization by segmental distraction osteogenesis will become a routine protocol and a popular method among orthodontic applications.Öğe Treatment of localized langerhans' cell histiocytosis of the mandible with intralesional steroid injection: report of a case(MOSBY-ELSEVIER, 2010) Esen, Alparslan; Dolanmaz, Dogan; Kalayci, Abdullah; Gunhan, Oemer; Avunduk, Mustafa CihatLocalized Langerhans cell histiocytosis (LLCH), formerly known as eosinophilic granuloma, mainly affects the skull, mandible, vertebrae, and ribs in children and the long bones of adults. Symptoms range from none to pain, swelling, and tenderness over the site of the lesion. General malaise and fever occasionally are present. Radiographically, lesions appear as radiolucent areas with well demarcated borders. LLCH may resolve spontaneously after biopsy in a period of months to years. However, if features include continuous pain, decrease of function, pathologic fractures, migration and resorption of teeth, or rapid progression, then active treatment needs to be considered. Treatment approaches include surgery, radiotherapy, chemotherapy, and intralesional injection of corticosteroids. In children with mandibular LLCH, 1 dose of methyprednisolone succinate injection has proven to be adequate. However, injections have not been performed in cases involving pathologic fracture. We report a new case of LLCH of the mandible that caused a pathologic fracture in an adult patient. Repeated intralesional corticosteroid injections resulted in fracture line disappearance within 14 months and lesion healing by the end of the 36-month follow-up. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e53-e58)
