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Öğe The effects of aflatoxin and glucomannan on coagulation parameters in rabbits(UNIV ZAGREB VET FACULTY, 2009) Donmez, Nurcan; Keskin, ErcanThe aim of this study was to evaluate the effects of aflatoxin and glukomannan on some coagulation parameters. In the study, 40 New Zealand rabbits were used and the rabbits were separated equally into four groups as control (C), glucomannan (G), glucomannan + aflatoksin (AG) and aflatoxin (A). At the end of the (10 week) experiment, MITT and PT values in group A were significantly (P<0.05) shorter than those in the control group. Fibrinogen concentrations were higher in groups A and AG than in the control group, but there was no significant difference between the groups. The thrombocyte count was significantly (P<0.05) increased in group A compared with the other groups. In conclusion, in this study this aflatoxin dose did not cause coagulation disorders as seen by shortness in PT and APTT levels. This might be explained by the fact that this dose stimulated the coagulation mechanism due to the slight negatively effect which initiated coagulation response.Öğe Effects of Aflatoxin on Some Haematological Parameters and Protective Effectiveness of Esterified Glucomannan in Merino Rams(HINDAWI LTD, 2012) Donmez, Nurcan; Donmez, H. H.; Keskin, E.; Kisadere, I.The objective of the present study was to evaluate the toxic effects of aflatoxin on some hematological parameters and to determine the preventive effectiveness of added glucomannan. In the study, 32 Merino rams were used, and the rams were separated equally to four groups as control (C), glucomannan (G), glucomannan + aflatoxin (AG), and aflatoxin (A). Erythrocyte, leukocyte count, hemoglobin, and hematocrit levels were decreased in A group compared with the other groups, and there was a reduction in similar parameters in AG group compared to control values. On the other hand, these parameters were tended to increase in AG group compared to A group values. Aflatoxicosis caused the lymphocytopenia and monocytopenia but increased percentage of neutrophil counts. In conclusion, the results determined in the study might be important to demonstrate the effects of aflatoxicosis and glucomannan on some haematological parameters before the clinical symptoms appear.Öğe Kırgızistan'da barındırılan evcil eşeklerde (equus asinus) bazı fizyolojik vehematolojik değerler ile anae pozitif lenfosit oranının belirlenmesi(2017) Kısadere, Ihsan; Kadyralıeva, Nariste; Cıhan, Huseyin; Sur, Emrah; Donmez, Nurcan; Oruc, ErtanBu çalışmanın amacı, Kırgızistandaki eşeklerin fizyolojik, hematolojik değerleriyle ANAE-pozitiflik oranının belirlenmesidir. Hayvanların (n24) genel klinik muayenesi yapıldı ve kan örnekleri alındı. Erkek ve dişi eşeklerin ortalama pulzasyon ve respirasyon oranları sırasıyla, 52.259.27; 49.164.80 atım/dk ve 18.414.21; 18.583.30 solunum/dk olarak ölçüldü. HGB, MCV, MCH ve MCHC değerlerinde gruplar arasında bir fark bulunamadı. RBC ve WBC değerleri dişilerde daha yüksek saptandı. Eşeklerin ANAE-pozitif PBL oranı %42.901.18 olarak belirlendi. Sonuç olarak, Kırgızistanda yaşayan eşeklere ait bazı fizyolojik, hematolojik ve ANAE-pozitiflik oranı belirlenmiş ve referans değer olarak sunulmuştur.Öğe Some physiological, hematological values and anae-positive lymphocyte rations of domestic donkeys (equus asinus) in Kyrgyzstan(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2017) Kisadere, Ihsan; Kadyralieva, Nariste; Cihan, Huseyin; Sur, Emrah; Donmez, Nurcan; Oruc, ErtanThe aim of this study was to determine the physiological, hematological parameters and ANAE positivity of donkeys in Kyrgyzstan. Animals (n=24) were clinically examined and blood samples were taken. The average pulsation and respiration rates of male and female donkeys were measured as 52.25 +/- 9.27; 49.16 +/- 4.80 beats/minute and 18.41 +/- 4.21; 18.58 +/- 3.30 breaths/minute, respectively. HGB, MCV, MCH and MCHC values did not different in the groups. RBC and WBC values were higher in females. Mean ANAE-positive PBL ratio of donkeys was found as 42.90 +/- 1.18%. Consequently, some physiological, hematological values and ANAE-profile were determined and advised as reference values of donkeys in Kyrgyzstan.