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    Effectiveness of Shear Wave Elastography in the diagnosis of acute pancreatitis on admission
    (SOC ROMANA ULTRASONOGRAFE MEDICINA BIOLOGIE-SRUMB, 2018) Durmaz, Mehmet Sedat.; Arslan, Serdar.; Ozbakir, Bora.; Gungor, Gokhan.; Tolu, Ismet.; Arslan, Fatma Zeynep.; Sivri, Mesut.; Koplay, M.
    Aim: We aimed to investigate the effectiveness of shear wave elastography (SWE) in the diagnosis of acute pancreatitis (AP). Material and methods: The pancreatic parenchyma of 50 patients whose clinical and laboratory findings were indicative of AP and of 70 healthy, asymptomatic volunteer participants with normal laboratory values was examined using SWE. Computed tomography was performed in all patients with AP on admission. Elastographic measurements were performed by manually drawing the contours of the pancreatic parenchyma using the free region of interest. The quantitative SWE values (meters/second [m/s], kilopascal [kPa]) of the patients and asymptomatic volunteers group were compared. Results: The mean SWE value of the pancreatic parenchyma was 2.60 +/- 1.63 m/s in the asymptomatic volunteers and 3.48 +/- 0.52 m/s in patients with AP, with a statistically significant difference (p < 0.001, t=-3.685). The mean SWE value of the pancreatic parenchyma was 23.77 +/- 6.72 kPa in the asymptomatic volunteers and 45.71 +/- 10.72 kPa in patients with AP, indicating a significant difference (p < 0.001, t=-3.685). AP can be diagnosed with a sensitivity and specificity of 98.0% when 29.45 kPa was designated as cut-off value and with a 96.0% sensitivity and 98.3% specificity when 2.77 m/s was designated as the cut-off value. The superiority of SWE was found over B-mode US and CECT in the diagnosis of AP on admission. Conclusion: SWE can be used as an effective imaging method with high sensitivity and specificity for the diagnosis of AP. It may be used as an important imaging method to assist in the diagnosis of AP especially when B-mode US and CECT findings are normal.
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    Experience of using shear wave elastography in evaluation of testicular stiffness in cases of male infertility
    (SPRINGER INTERNATIONAL PUBLISHING AG, 2020) Erdoğan, Hasan.; Durmaz, Mehmet Sedat.; Özbakır, Bora.; Cebeci, Hakan.; Özkan, Deniz.; Gökmen, İbrahim Erdem.
    Purpose The purpose of this study was to determine quantitative testicular tissue stiffness values in normal and infertile men using shear wave elastography (SWE), and to evaluate the relationship between infertility and testicular stiffness value. Methods In total, 100 testes of 50 infertile patients with abnormal semen parameters were classified as group A, and 100 testes of 50 control subjects were classified as group B. These two groups were compared in terms of age, testicular volume, and SWE values. The group B testes were randomly chosen from patients who had applied for ultrasonography for any reason, and who had no testis disease and no history of infertility. Results The mean age of the patients was 27.83 years, and no significant difference in age was found between the groups (P = 0.133). No significant difference in testicular volume was found between the groups (P = 0.672). The SWE values were significantly higher in group A than in group B (P = 0.000 for both m/s and kPa values). SWE values had a negative correlation with mean testicular volume in group A (for m/s values: P = 0.043; for kPa values: P = 0.024). Conclusion SWE can be a useful technique for assessing testicular stiffness in infertile patients to predict parenchymal damage in testicular tissue that leads to an abnormality in sperm quantity. In addition, decreased testicular volume, together with increased SWE values, can reflect the degree of parenchymal damage.
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    Two-dimensional shear wave elastography in the assessment of salivary gland ınvolvement in primary sjogren's syndrome
    (WILEY, 2019) Arslan, Serdar.; Durmaz, Mehmet Sedat.; Erdogan, Hasan.; Esmen, Serpil Ergulu.; Turgut, Bekir.; Iyisoy, Mehmet Sinan.
    Objectives The aim of this study was to investigate the diagnostic performance of two-dimensional (2D) shear wave elastography (SWE) in the assessment of salivary gland involvement in primary Sjogren's syndrome (pSS). Methods Fifty-three patients with pSS and 30 healthy volunteers were included. The echogenicity of all submandibular and parotid glands was evaluated with B-mode ultrasound, and their elasticity was assessed with 2D SWE. The mean and standard deviation of the shear wave speed and elasticity modes on 2D SWE were calculated. Results The mean shear wave speed and elasticity mode values for the submandibular and parotid glands were significantly higher in the patients with pSS (P < .05). The mean elasticity of the shear wave speed mode was best able to differentiate the parotid glands of patients with pSS from those of healthy volunteers at a cutoff value of 2.48 m/s, whereas the mean elasticity of the elasticity mode was best able to differentiate the submandibular glands of patients with pSS from those of healthy volunteers at a cutoff value of 21 kPa. Conclusions Two-dimensional SWE is an effective technique for assessment of the parenchyma of the salivary glands in patients with pSS and predicts interstitial fibrosis and the severity of histologic damage.