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Öğe Amiodarone may increase survival rate in tilmicosin-induced lethal toxicity(WILEY-BLACKWELL, 2012) Er, A.; Tras, B.; Cetin, G.; Dik, B.[Abstract not Available]Öğe Doxycycline and meloxicam can treat neuroinflammation in rat brain(WILEY, 2018) Coskun, D.; Dik, B.; Bahcivan, E.; Er, A.[Abstract not Available]Öğe Effect of flunixin meglumin on the antioxidant status in endotoxemia(SCIENDO, 2007) Konyalioglu, S.; Er, A.; Uney, K.; Elmas, M.; Yazar, E.In this study, the effects of flunixin meglumin on the antioxidant status during endotoxemia were investigated. Thirty Balb/C mice were divided into three equal groups. Mice with no treatment formed the control group (group I). Mice treated with lipopolysaccharide (LPS) and LPS + flunixin meglumin (FM) formed groups II and III, respectively. An mice were sacrificed and tissue samples were collected 6 hours after treatments. Activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), as well as levels of malondialdehyde (MDA) and glutathione (GSH) were determined spectrophotometrically. LPS caused a significant (p < 0.05) increase in levels of MDA (heart, kidney, spleen) which is an accepted biomarker of oxidative stress, and changed the levels of SOD, GPX, CAT and GSH. When FM was administered simultaneously with LPS, FM inhibited (p < 0.05) the increase of MDA levels in an tissues. As results, LPS caused MDA levels and oxidative stress to increase. However, FM depressed the LPS induced increase of MDA levels. This antioxidant effect of FM may be beneficial in endotoxemia.Öğe Effect of tilmicosin on serum cytokine productions(WILEY-BLACKWELL PUBLISHING, INC, 2009) Elmas, M.; Er, A.; Avci, G. E.; Bulbul, A.; Uney, K.; Yazar, E.[Abstract not Available]Öğe Effects of enrofloxacin, flunixin meglumine and dexamethasone on disseminated intravascular coagulation and cytokine levels in endotoxemia(WILEY-BLACKWELL PUBLISHING, INC, 2009) Elmas, M.; Bulbul, A.; Avci, G. E.; Er, A.; Uney, K.; Yazar, E.; Tras, B.[Abstract not Available]Öğe Effects of Tarantula cubensis alcoholic extract and Nerium oleander distillate on experimentally induced colon cancer(ECOLE NATIONALE VETERINAIRE TOULOUSE, 2019) Er, A.; Ozdemir, O.; Coskun, D.; Dik, B.; Bahcivan, E.; Faki, H. Eser; Yazar, E.The aim of this research was to determine the effects of Tarantula cubensis alcoholic extract (TCAE) and Nerium oleander distillation (NOD) on the colon aberrant cryptal foci (ACF) score, serum cytokines [Tumour necrosis factor (TNF)-alpha, interleukin (IL)-2, IL-6, IL-10], prostaglandin E2, and oxidative status parameters (malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase) in an experimentally induced colon cancer model in rats. Male rats (38 in total) were divided into 4 groups: Control group (n = 8), Colon Cancer group (CC, n = 10), CC+TCAE group (n = 10), and CC i NOD group (n = 10). Except for the Control group, the rest of rats received azoxymethane (15 mg/kg, SC) once a week for two weeks to induce colon cancer. TCAE was administered once a week at 0.2 mL/kg (SC) and NOD was administered in water to CC+TCAE and CC+NOD groups for 18 weeks. After blood samples were collected, the rats were euthanized, colons were removed, washed with saline, then fixed with 10% formaldehyde, and stained with 0.2% methylene blue. ACFs were scored by light microscopy. Serum levels of cytokines, prostaglandin E2, and oxidative status parameters were determined with ELISA. ACF score of the CC group was higher than CC+TCAE and CC+NOD groups. The prostaglandin E2 level of the Control group was lower than the CC i TCAE group, while IL-2 and IL-10 levels of the Control group were lower than all other groups. In conclusion, it can be stated that TCAE and NOD applications may be beneficial in the treatment of colon cancer.Öğe Transition probabilities of neutral scandium(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2014) Ozturk, I. K.; Celik, G.; Gokce, Y.; Atalay, B.; Guzelcimen, F.; Er, A.; Basar, G.The electric dipole transition probabilities and the oscillator strengths of neutral scandium have been calculated using the quantum defect orbital theory and the Cowan code for the 3d4s(2)-3d4s4p, 3d(2)4s-3d(2)4p, and 3d4s(2)-4s(2)4p transitions. In addition, a parametric analysis of the fine structure for the 3d4s(2) configuration of even parity is performed using Cowan code. The transition probabilities and the oscillator strengths obtained in this work are mostly in agreement with the data obtained from different theoretical works given in the literature. Moreover, transition probabilities for 24 levels of neutral scandium are given for the first time.
