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Öğe The effects of rHuEPO administration on pulmonary functions in haemodialysis patients(WICHTIG EDITORE, 1996) Uçok, K; Gökbel, Hakkı; Yeksan, M; Bediz, C. S.; Eser, C; Türk, S; Ergene, NThe aim of this study was to investigate the effects of erythropoietin therapy on pulmonary functions in haemodialysis patients. Thirteen patients with chronic renal failure on regular haemodialysis and in need of treatment for anaemia were treated with 45-60 U/kg erythropoietin three times a week. Thirteen haemodialysis patients constituted the control group. Patients receiving erythropoietin were given pulmonary function tests prior to the treatment and after Hb levels had reached 10 g/dl. The interval between first and second pulmonary function tests was similar for both the control group and the erythropoietin group. There was no significant difference between the results of the first and the second pulmonary function tests of the control group. However, in the erythropoietin group, the diffusing capacity, maximal voluntary ventilation, forced vital capacity and peak expiratory flow rate values increased significantly. The existence of a relationship between the diffusing capacity and anaemia is well known. Rises in other parameters following erythropoietin administration might be the result of a gain in respiratory muscle strength consequent to aneamia correction.Öğe Electroacupuncture therapy for weight loss changes plasma lipoprotein(a), apoprotein A and apoprotein B levels in obese women(FEDERATION AMER SOC EXP BIOL, 2005) Cabioolu, MT; Ergene, N; Soylu, R[Abstract not Available]Öğe Electroacupuncture therapy for weight loss reduces serum total cholesterol, triglycerides, and LDL cholesterol levels in obese women(WORLD SCIENTIFIC PUBL CO PTE LTD, 2005) Cabioglu, MT; Ergene, NOur purpose in this study was to investigate the effect of acupuncture therapy on body weight and on levels of the serum total cholesterol, triglyceride, high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol in obese women. Fifty-five women were studied in three groups as follows: (1) control group (n = 12; mean age = 43.3 +/- 4.3, and mean body mass index {BMI} = 32.2 +/- 3.4); (2) electroacupuncture (EA) (n = 22; mean age = 39.8 +/- 5.3, and BMI = 34.8 +/- 3.3); and (3) diet restriction (n = 21; mean age = 42.7 +/- 3.9, and BMI = 34.9 +/- 3.3). EA was performed using the ear points, Sanjiao (Hungry) and Shen Men (Stomach), and the body points, LI 4, LI 11, St 25, St 36, St 44 and Liv 3, once daily, for 30 minutes, for 20 days, whereas patients on diet restriction had a 1425 Kcal diet program, that consisted of 1425 Kcal daily for 20 days. There was a 4.8% weight reduction in patients with EA application, whereas patients on diet restriction had a 2.5% weight reduction. There were significant decreases in total cholesterol and triglyceride levels in EA and diet groups compared with the control group (p < 0.05 in both cases). Furthermore, there was a decrease in LDL levels in the EA group compared with the control group (p < 0.05). No significant changes could be found in HDL levels among the three groups. Our results suggest that EA application in obese women may decrease the serum total cholesterol, triglyceride, and LDL cholesterol levels by increasing the serum beta endorphin level. This lipolytic effect of EA may also reduce the morbidity of obesity by mobilizing the energy stores that result in weight reduction.Öğe Electroacupuncture treatment for weight reduction and subjective sleep quality in obese subjects(FEDERATION AMER SOC EXP BIOL, 2005) Cabioolu, MT; Ergene, N; Ozturk, L[Abstract not Available]Öğe The mechanism of acupuncture and clinical applications(TAYLOR & FRANCIS LTD, 2006) Cabyoglu, MT; Ergene, N; Tan, UThis study presents the result of the studies explaining the effects of acupuncture on various systems and symptoms. It has been determined that endomorphin-1, beta endorphin, encephalin, and serotonin levels increase in plasma and brain tissue through acupuncture application. It has been observed that the increases of endomorphin-1, beta endorphin, encephalin, serotonin, and dopamine cause analgesia, sedation, and recovery in motor functions. They also have immunomodulator effects on the immune system and lipolitic effects on metabolism. Because of these effects, acupuncture is used in the treatment of pain syndrome illnesses such as migraine, fibromyalgia, osteoarthritis, and trigeminal neuralgia; of gastrointestinal disorders such as disturbance at gastrointestinal motility and gastritis; of psychological illnesses such as depression, anxiety, and panic attack; and in rehabilitation from hemiplegia and obesity.Öğe The treatment of obesity by acupuncture(TAYLOR & FRANCIS LTD, 2006) Cabyoglu, MT; Ergene, N; Tan, UThe present study is an investigation of the results of the studies on the effects of acupuncture application therapy on obesity. It has been reported that acupuncture application in obesity treatment is effective in procuring weight loss. It can affect appetite, intestinal motility, and metabolism, as well as emotional factors such as stress. Increases in neural activity in the ventromedial nuclei of the hypothalamus, in tone in the smooth muscle of the stomach and in levels of enkephalin, beta endorphin, and serotonin in plasma and brain tissue have also been observed with the application of acupuncture. It has been observed that acupuncture application to obese people increases excitability of the satiety center in the ventromedial nuclei of the hypothalamus. Acupuncture stimulates the auricular branch of the vagal nerve and raises serotonin levels. Both of these activities have been shown to increase tone in the smooth muscle of the stomach, thus suppressing appetite. Among other things, serotonin enhances intestinal motility. It also controls stress and depression via endorphin and dopamine production. In addition to these effects, it is thought that the increase in plasma levels of beta endorphin after acupuncture application can contribute to the body weight loss in obese people by mobilizing the body energy depots through lipolithic effect.
