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Öğe Necrotizing pneumonia caused by Streptococcus pneumoniae serotype 3 despite PCV13(SOC ARGENTINA PEDIATRIA, 2019) Alkan, Gülsüm; Emiroğlu, Melike; Dağı, Hatice T.; Gürbüz, Venhar; Ceyhan, MehmetStreptococcus pneumoniae is the most common cause of complicated pneumonia. Pneumococcal necrotizing pneumonia (PNP) is a rare and serotype related complication. Serotypes 1, 3, 14, 15, 19A and 33 were the most reported serotypes in children with PNP before immunization. Despite widespread vaccination, S. pneumoniae is still cause of invasive diseases. We reported a child, fully immunized with 13-valent conjugated pneumococcal vaccine (PCV13) who was diagnosed PNP due to serotype 3. Breakthrough invasive infection caused by S. pneumoniae must be considered in mind despite fully vaccination.Öğe Surveillance of penicillin resistance of Neisseria meningitidis strains from invasive infections between 2013 and 2018 in Turkey(TAYLOR & FRANCIS LTD, 2020) Öncel, Eda Karadağ; Ceyhan, Mehmet; Başaranoğlu, Sevgen Tanır; Gürbüz, Venhar; Aycan, Ahmet Emre; Özsürekci, Yasemin; Kurugöl, Zafer; Emiroğlu, Melike Keser; Devrim, İlker; Karbuz, Adem; Akışoğlu, Havva Özlem Altay; Gürler, NezahatNeisseria meningitidis (N. meningitidis) is regarded as the leading cause of bacterial meningitis in many regions of the world. The empiric antimicrobial treatment is mainly based on antimicrobial resistance and patient characteristics. We aimed to analyze susceptibility patterns of N. meningitidis strains isolated in Turkey. Invasive meningococci collected in a multicenter, hospital-based, epidemiological surveillance study of pediatric (0-18 years of age) bacterial meningitis cases between 2013 and 2018 were studied. Five isolates (8.7%) displayed resistance to penicillin-G, while 13 isolates (22.8%) had intermediate susceptibility. All isolates were cefotaxime and rifampin susceptible. The data shows appropriateness of third-generation cephalosporins in empirical use for meningococcal infections in children. Since Turkey is located in a transition zone geographically, surveillance reports are very crucial.