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    Comparison of instilled lidocaine and procaine effects on pain relief in dogs undergoing elective ovariohysterectomy
    (ISRAEL VETERINARY MEDICAL ASSOC, 2019) Kibar, M.; Tuna, B.; Kısadere, İ.; Güzelbekteş, H.
    The aim of the present study was to compare the analgesic efficacy of instilled intra-peritoneal lidocaine and procaine during the perioperative and the postoperative periods in dogs undergoing elective ovariohysterectomy (OVH). Twenty-four sexually intact female dogs were referred for OVH. Following the laparotomv procedure the L group received intraperironeal instillation of 3.5 mg/kg of 0.2% lidocaine. The therapeutic agent was administreted over the area of ovaries, broad ligament, and uterine stump. It was injected using a syringe and needle (23 G). The P group administered intraperitoneal instillation of 3.5 mg/kg of 0.2% procaine and the control group received 1.75 ml/kg of intraperitoneal saline in a similar fashion. Groups L and P had significantly lower Glascow Composite Measure Pain Scale scores (CMPS-SF) than the control group at the 0.5, 1,2, 3, 8, and 24 hour postoperative periods. In conclusion, administerstration of intraperitoneal installation of lidocaine and procaine were shown to provide a milady significant effect in reducing intraoperative and postoperative pain and biochemical stress responses within 3 hours of surgery.
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    Prevalence of Gastroesophageal Reflux Disease in Premature Calves
    (WILEY-BLACKWELL, 2012) Güzelbekteş, H.; Coşkun, A.; Ok, M.; Aydoğdu, U.; Şen, I.
    Background Gastroesophageal reflux (GER) is the presence of gastric contents proximal to the stomach. Pathologic consequences secondary to GER are termed gastroesophageal reflux disease (GERD). Objectives The purpose of this study was to determine the prevalence of GER and GERD in premature calves by endoscopic examination. Animals Ten healthy and 51 premature calves were included in the study. All premature calves also had respiratory distress syndrome. Methods Esophagoscopy of premature calves was conducted by fiber optic endoscopy. Abnormalities such as increased saliva, hyperemia, hemorrhage, petechiae, presence of abomasal content in the esophagus, and relaxation of the lower esophageal sphincter (LES) were evaluated by endoscopy. Results The prevalence of GERD and GER in the premature calves was 55 and 67%, respectively. Hyperemia and hyperemia with hemorrhage or petechiation of the esophageal mucosa were determined by endoscopic examination. Hyperemia was commonly observed in the distal esophageal mucosa, although a few hyperemic areas also were observed in other portions of the esophagus. In addition to these abnormalities, LES relaxation, abomasal fluid in the distal esophagus, abomasal content in the esophagus, and increased saliva also were observed in premature calves with GER. Conclusions The prevalence of both GER (67%) and GERD (55%) in premature calves was high in the study. Endoscopy provides a practical, rapid, noninvasive, and reasonably accurate method for determining the presence of GER and GERD in premature calves.