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Öğe HPV TYPES AND THE RELATION OF HPV PREVALENCE TO RISK FACTORS AND CERVICAL SMEAR IN WOMEN AT RISK FOR CERVICAL CANCER(NOBEL ILAC, 2011) Eroglu, Celalettin; Kesli, Recep; Eryilmaz, Mehmet Ali; Unlu, Yasar; Gonenc, Oguzhan; Celik, CetinObjective: In this study, the aim was to determine HPV prevalence, types of HPV and the relationship between HPV positivity and the risk factors for developing cervical cancer and cervical smear in women at risk for cervical. cancer Material and Method: Four hundred and four healthy women who applied for the screening of cervical cancer and who were at risk were enrolled in the study All subjects were retrospectively investigated in terms of the risk factors for cervical cancer The presence of HPV was determined and the most frequently encountered 16 types of HPV were identified, using Reverse Hybridization Method. Cervical smear samples were obtained via conventional method and assessed with 2001 Bethesda system. Results: The median age of the subjects was 37 (27-62) and HPV frequency 32.5% (n=131). The most frequent types of HPV were HPV 18 in 60 cases (45.8%) and HPV 16 in 22 cases (16.8%). According to HPV types, high risk rate for cervical cancer was found to be 78.7% (n=103). Of the variables of the risk factors, the presence of genital condyloma was observed as the most important risk factor Conclusion: It was found that the women at risk for cervical cancer showed high positivity rate, especially in oncogenic HPV types.