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    Course of panic disorder during the early postpartum period: a prospective analysis
    (W B SAUNDERS CO-ELSEVIER INC, 2008) Guler, Ozkan; Koken, Gulengul N.; Emul, Murat; Ozbulut, Omer; Gecici, Omer; Uguz, Faruk; Gezginc, Kazim
    Purpose: Most of the studies about course of panic disorder (PD) after childbirth have a retrospective nature. The aim of the current study was to examine prospectively the clinical course of 13 pregnant women with a diagnosis of PD across pregnancy and the early postpartum period. Method: The diagnosis of PD was determined by means of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders in the third trimester of pregnancy. Within the same period, the Panic and Agoraphobia Scale was used to determine the severity of PD. The last assessment with both instruments was performed at 6 weeks postnatally. Results: Of these 13 women, 6 (group 1) reported that PD developed during the 6th to the 28th week of their gestation, and the number of women who experienced PD symptoms before pregnancy (group 2) was 7. It was found that the severity of panic symptoms considerably decreased in the total sample, group 1, and group 2 from the basal levels to 6 weeks postnatally. Conclusion: Our study results suggest that pregnant women with PD may experience a marked improvement in PD symptoms in the early postpartum period. (c) 2008 Elsevier Inc. All rights reserved.
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    Longitudinal assessment of symptom and subtype categories in obsessive-compulsive disorder
    (WILEY-LISS, 2007) Besiroglu, Lutfullah; Uguz, Faruk; Ozbebit, Ozgur; Guler, Ozkan; Cilli, Ali Savas; Askin, Rustem
    Although it has been postulated that symptom subtypes are potential predictors of treatment response, few data exist on the longitudinal course of symptom and subtype categories in obsessive-compulsive disorder (OCD). Putative subtypes of OCD have gradually gained more recognition, but as yet there is no generally accepted subtype discrimination. Subtypes, it has been suggested, could perhaps be discriminated based on autogenous versus reactive obsessions stemming from different cognitive processes. In this study, our aim was to assess whether symptom and subtype categories change over time. Using the Yale-Brown Obsessive Compulsive Symptom Checklist (Y-BOCS-SC), we assessed 109 patients who met DSM-IV criteria for OCD to establish baseline values, then reassessed 91 (83%) of the initial group after 36 +/- 8.2 months. Upon reassessment, we found significant changes from baseline within aggressive, contamination, religious, symmetry and miscellaneous obsessions and within checking, washing, repeating, counting and ordering compulsion categories. Sexual, hoarding, and somatic obsessions, and hoarding and miscellaneous compulsions, did not change significantly. In accordance with the relevant literature, we also assigned patients to one of three subtypes-autogenous, reactive, or mixed groups. Though some changes in subtype categories were found, no subtype shifts (e.g., autogenous to reactive or reactive to autogenous) were observed during the course of the study. Significantly more patients in the autogenous group did not meet OCD criteria at follow-up than did patients in the other groups. Our results suggest that the discrimination between these two types of obsession might be highly valid, because autogenous and reactive obsessions are quite different, both in the development and maintenance of their cognitive mechanisms, and in their outcome.
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    Major depressive disorder comorbid severe hydrocephalus caused by Arnold-Chiari malformation
    (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2017) Kandeger, Ali; Guler, Hasan Ali; Egilmez, Umran; Guler, Ozkan
    [Abstract not Available]
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    Pregnancy-Onset Panic Disorder: Incidence, Comorbidity and Associated Factors
    (AVES, 2015) Guler, Ozkan; Kaya, Veli; Gezginc, Kazim; Kayhan, Fatih; Cicek, Erdin; Sonmez, Onder; Uguz, Faruk
    Introduction: The present study aimed to investigate the incidence rate of pregnancy-onset panic disorder (POPD) among Turkish pregnant women using a diagnostic interview. Additionally, we examined whether the independent socio-demographic or clinical risk factors were associated with the risk of panic disorder in these women. Methods: The study sample comprised 1475 consecutive pregnant women who presented to the obstetric outpatient clinics of two research centers. The rate of POPD in these participants was 1.3% (Group 1, n= 20). The 20 women with POPD were compared with 250 pregnant women without pregnancy-onset depression or anxiety (Group 2; controls). Panic disorder and other anxiety or mood disorders were determined by means of the Structured Clinical Interview for DSM-IV. Comorbid Axis II disorders were diagnosed with the Structured Clinical Interview for DSM-III-R Personality Disorders. Results: The incidence rate of panic disorder was 1.3% (n= 20). In group 1, 55% (n= 11) of the women with POPD had an additional mood or anxiety disorder. In addition, the prevalence rate of any cluster C personality disorder, including avoidant, passive-aggressive and obsessivecompulsive personality disorders, were significantly greater in the group 1 women with POPD than the control pregnant women without a panic disorder (group 2). Conclusion: The women with POPD were more likely than the controls to have a cluster C Axis II disorder and a history of a pre-existing anxiety or mood disorder.
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    The prevalence of panic disorder in pregnant women during the third trimester of pregnancy
    (W B SAUNDERS CO-ELSEVIER INC, 2008) Guler, Ozkan; Sahin, Figen Kir; Emul, H. Murat; Ozbuut, Omer; Gecici, Omer; Uguz, Faruk; Gezginc, Kazim
    Objective: The principal aim of this study was to assess the current prevalence rate of panic disorder (PD) in pregnant women during the third trimester of pregnancy. The second aim of the present study was to investigate the clinical characteristics of PD in pregnant and nonpregnant women. Method: The study data were gathered from 512 consecutive women in the third trimester of pregnancy who were admitted to the obstetric outpatient clinics of 2 university research centers. The diagnosis of PD was determined by means of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I disorders in the third trimester of pregnancy. Within the same period, the Panic and Agoraphobia Scale was used to determine the severity of PD. In addition, we compared the clinical characteristics of PD in gravid subjects (n = 13) with their control group. A control group was composed of 19 consecutive nonpregnant female outpatients diagnosed with PD who presented to the psychiatric outpatient clinics of the same hospitals. Results: The prevalence rate of PD was found to be 2.5% (n = 13) among the subjects in the third trimester of pregnancy. Of these 13 pregnant, 7 subjects reported that PD developed during the 6th to 28th weeks of their gestation, and the number of subjects who experienced PD symptoms before pregnancy was 6. In addition, there was no statistically difference between gravid and nongravid PD cases with regard to the severity of panic symptoms. Conclusion: Our study suggests that PD may be common among pregnant females during the third trimester of pregnancy and seems to be associated with similar clinical features during gestation and nongestation. (c) 2008 Elsevier Inc. All rights reserved.
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    Self-Reported Data on Sleep Quality and Psychologic Characteristics in Patients with Myofascial Pain and Disc Displacement Versus Asymptomatic Controls
    (QUINTESSENCE PUBLISHING CO INC, 2012) Sener, Sevgi; Guler, Ozkan
    Purpose: The aim of this research was to compare the differences between patients with myofascial pain and disc displacement and asymptomatic individuals based on aspects of psychologic status and sleep quality. Materials and Methods: One hundred thirty patients (81 women, 49 men; mean ages: 30.0 and 31.0 years, respectively) with temporomandibular disorder were selected, and 64 control subjects (32 women, 32 men; mean ages: 27.2 and 27.5 years, respectively) were included in the investigation over a period of 1 year. Clinical diagnosis of 65 patients with myofascial pain and 65 patients with disc displacement with or without limitation and joint pain was determined according to the Research Diagnostic Criteria for Temporomandibular Disorders. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality. Psycho logic status was assessed using Symptom Checklist-90-Revised (SCL-90-R). Chi-square, Kolmogorov-Smirnov, one-way analysis of variance, and Tukey Honestly Significant Difference post hoc multiple comparison or Tamhane T-2 tests were used for statistical analysis. Results: There was a significant difference between patients with myofascial pain and disc displacement regarding somatization and paranoid ideation. No statistically significant difference was found between patients with disc displacements and controls in all dimensions of the SCL-90-R. Total score for the PSQI was statistically significantly different between patients with myofascial pain and controls; no significant differences were found between patients with disc displacement and those with myofascial pain or controls regarding the PSQI. Conclusion: To manage patients with myofascial pain, psychologic assessments including sleep quality should be considered. Int J Prosthodont 2012;25:348-352.
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    Temperament-Character Profiles in Patients with Alopecia Areata
    (KURE ILETISIM GRUBU A S, 2013) Annagur, Bilge Burcak; Bilgic, Ozlem; Simsek, Kismet Kaya; Guler, Ozkan
    Objective: Alopecia areata (AA) is a chronic immunological skin disorder characterized by round or oval patches of non-scarring hair loss. Current psychosomatic medicine focuses on the triggering of various diseases by stress and on psychoimmunological changes related to psychosocial stress. There has been little research on the personality traits in alopecia areata. The aim of this study is to examine temperament character profiles and psychopathology of AA patients and to compare the findings with healthy controls. Method: Seventy-three patients who applied to outpatient clinics of dermatology for AA were included. The control group (n=78) was recruited from a non-clinical population. General psychopathology was assessed with the revised version of the Symptom Checklist-90 (SCL-90-R). Personality was assessed using the Temperament and Character Inventory (TCI). Results:The Global Severity Index (GSI) and depression subscale of the SCL-90-R scores were higher in the AA than in the control group (p<0.05). Total scores of novelty seeking (NS), reward dependence (RD), and self-transcendence. (ST) of the patient groups were significantly lower than those of the control groups (p<0.05). When depression and anxiety were considered as covariates, the significant difference which was detected by the t-test still existed between the two groups in terms of NS, RD and ST. Conclusion: It is well known that psychiatric symptoms are common in AA. This study suggests that AA patients have distinctive temperaments such as novelty seeking, reward dependence and self-transcendence dimension compared with healthy controls. AA patients with low NS, RD and ST scores may be prone to depression.