Yazar "Gunes, Erdogan" seçeneğine göre listele

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    Application of reproductive biotechnologies for sustainable production of livestock in Turkey
    (SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK, 2018) Kaya, Abdullah; Gunes, Erdogan; Memili, Erdogan
    Reproductive biotechnology encompasses powerful tools to enhance the efficiency and profitability of livestock reproduction, production, and product quality. These technologies include genomic selection, evaluation of semen (from bulls, bucks, and rams) using advanced cell and molecular technologies, semen cryopreservation and artificial insemination, estrus synchronization, superovulation of the females (cows, dams, and ewes), ovum pick-up, in vitro fertilization and embryo culture, embryo transfer, and pregnancy detection. The extent of applications of these modern technologies and their economic impacts for livestock production in Turkey are elusive. As a result, there is an urgent need for sound economic analyses, research and education, training of animal producers to facilitate technology transfer, and informing of the public of the benefits of animal biotechnology. The objective of this study was to provide a review of key reproductive technologies and economic analyses of them, followed by an outlook on the future production of cattle, goats, and sheep in Turkey. This review is an important resource for students, researchers, and producers for a better understanding and for the application of cutting-edge biotechnology in efficient, sustainable, and profitable livestock production.
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    CHARACTERIZATION OF UROPATHOGENIC ESCHERICHIA COLI STRAINS: ANTIBIOTIC RESISTANCE PATTERNS, DETECTION OF ESBL GENES AND INTERACTIONS BY LYTIC PHAGES
    (PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2018) Uysal, Ahmet; Gunes, Erdogan; Arslan, Emine; Durak, Yusuf
    In this study, 97 Escherichia coli strains isolated from urinary tract infections were evaluated in terms of phenotypic diversity, susceptibility to sixteen antibiotics, and extended spectrum of beta lactamase (ESBL) characteristics. The bacteriophage interactions was used to identify the relations of the E.coli isolates. Results showed that 21 of the 76 typable strains revealed 19 different phage types. Phage types of 21 strains could not be determined. Antibiotic susceptibility tests, performed against sixteen antibiotics, showed that although the isolates revealed 44 different types of resistance profiles, the strains showed the greatest resistance to cephalothin (54.6%), followed by tetracycline (53.6%), nalidixic acid (44.3%), and aztreonam and ofloxacin (29.8%). There was no resistance to amikacin and meropenem, and all strains were susceptible to meropenem. ESBL detection conducted by double disc synergy and multiplex polymerase chain reaction methods showed that 13 of 97 (13.4%) strains were ESBL-producing. Of the 13 ESBL-producing isolates, two carried bla(CTX-M), six bla(TEM), five bla(OXA), and one bla(TEM) and bla(SHV) at same time. We concluded that lytic phages could not be successful for typing the strains phenotypically. The monitoring of antimicrobial resistance levels and antimicrobial usage in humans should be an integral part of the prevention and control of antimicrobial resistance.
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    Investigation mutagenic and antimutagenic potentials of root methanol extract of Ferula elaeochytris Korovin by salmonella/microsome test system
    (ELSEVIER SCIENCE BV, 2016) Durak, Yusuf; Uysal, Ahmet; Gunes, Erdogan
    [Abstract not Available]
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    Investigation of Methicillin Resistance of Staphylococcus aureus Strains Isolated from Various Sources by Different Methods
    (DR M N KHAN, 2013) Gunes, Erdogan; Durak, Yusuf
    Object of this study is to determine methicillin resistance of 150 strains of Staphylococcus aureus isolated and identified from various sources by the methods of oxacillin agar screen, broth microdilution and oxacillin disc diffusion, to compare sensitivity and specificity of these methods by making oxacillin agar screen test reference and to determine multi-antibiotic resistance in these strains. 16 (10.7%) of the 150 strains were determined as Methicillin-Resistant S.aureus (MRSA) through the methods of agar screen and microdilution while 17 (11.3%) strains were found as the same through the method of disc diffusion. Agar screen and microdilution methods were found as 100% compatible with each other. Sensitivity of the disc diffusion method was calculated as 100% while its specificity was calculated as 99.2%. Antibiotic susceptibility tests conducted by using the disc diffusion method against 10 antibiotics showed that the highest resistances of MRSA and MSSA (Methicillin-Susceptible S. aureus) strains were determined as 100% and 93.3% to penicillin, 81.2% and 5.2% to tetracycline, 62.5% and 1.5% to ofloxacin, 56.2% and 0.7% to rifampin respectively while all strains were found susceptible to linezolid and vancomycin. It was seen that multiple-antibiotic resistance in MRSA strains are higher compared with that in MSSA strains. It has been thought that linezolid may be an alternative for vancomycin in curing MRSA infections.
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    New Prospective Materials for Chemoprevention: Three Phlomis
    (SCIENCEDOMAIN INT, 2016) Uysal, Ahmet; Gunes, Erdogan; Sarikurkcu, Cengiz; Celik, Handan; Durak, Yusuf; Uren, Mehmet Cemil
    Aim: Plants are permanent sources of biologically active compounds, used by about 80% of the world population as manufactured drugs. The aims of this paper are to determine the mutagenic and antimutagenic activities of methanol, ethyl acetate and water extracts from Phlomis nissoli (PNM, PNE, PNW) Phlomis pungens var. pungens (PPM, PPE, PPW) and Phlomis armeniaca (PAM, PAE, PAW) against well-known mutagens. Methodology: Mutagenic/antimutagenic activities were determined by Ames test. Results: Extracts of P. nissoli, P. pungens and P. armeniaca were not mutagenic against TA98 and TA100 in the condition both with and without S9 mix. The strongest antimutagenic action was revealed by PNE extract at a dose of 5000 mu g/plate against 2-amino-flourene with 96% inhibition for TA98 with S9 mix. PNM extract alleviated the mutagenic action of 2-amino-anthracene and exhibited strong inhibition rates (93%, 78%, 57%, respectively) with S9 mix at all doses for TA100 strain. While PAE extract manifested 95%, 91% and 84% inhibition against 2-amino-flourene for TA98, it revealed 90%, 84%, and 87% inhibition ratios, respectively, making them as strongly antimutagenic against 2-amino-anthracene for TA100 with S9 mix. Conclusion: P. nissoli, P. pungens and P. armeniaca extracts have significant antimutagenic capacities and they can represent a good model for the development of new drug formulations in pharmaceutical industry and they could be used in food industry as chemoprevention agent.