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    Intravenous Thrombolytic Therapy in Acute Stroke: Frequent Systemic Problems and Solutions
    (TURKISH NEUROLOGICAL SOC, 2018) Topcuoglu, Mehmet Akif; Arsava, Ethem Murat; Ozdemir, Atilla Ozcan; Gurkas, Erdem; Orken, Dilek Necioglu; Ozturk, Serefnur
    One of the most important reasons why the use of the intravenous (IV) tissue plasminogen activator (tPA), which is one of the key elements of acute ischemic stroke treatment, is not sufficiently widespread is the fact that many common questions have not been adequately answered. In this review, questions about systemic non-neurologic conditions, problems related with IV tPA treatment and complications of treatment, which were collected from our colleagues practicing in Turkey and which are more important in clinical practice, were answered on the basis of the current literature and clear recommendations are made.
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    Intravenous Thrombolytic Therapy in Acute Stroke: Problems and Solutions
    (TURKISH NEUROLOGICAL SOC, 2017) Topcuoglu, M. Akif; Arsava, E. Murat; Ozdemir, A. Ozcan; Gurkas, Erdem; Orken, Dilek Necioglu; Ozturk, Serefnur
    Use of intravenous tissue plasminogen activator (tPA) is one of the key elements of acute ischemic stroke management. Its use has not become widespread, and has faced significant problems in our country for more than a quarter of a century most probably due to many unanswered questions about issues related with daily practice. However, recent developments, which adequately focused and found solutions for most of these problems and questions, have led to a major change of point of view and understanding of the hyperacute management of stroke. This article, in the light of the relevant literature, discusses and provides clear recommendations for questions directed by neurologists practicing in Turkey mainly about typical neurologic issues faced in the setting of tPA use for acute stroke.