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Öğe Biomechanical evaluation of different fixation systems after Le Fort I osteotomy in polyurethane models of unilateral clefts(CHURCHILL LIVINGSTONE, 2016) Esen, Alparslan; Isik, Kubilay; Saglam, Haci; Ozdemir, Yusuf Bugra; Dolanmaz, DoganWe compared the stability of three different titanium plate-and-screw fixation systems after Le Fort I osteotomy in polyurethane models of unilateral clefts. Thirty-six models were divided into 3 groups. In the first group, we adapted standard Plates 1 mm thick with 2.0 mm screws and placed them bilaterally on the zygomatic buttress and the piriform rim. In the second group, we did the same and added Plates 0.6 mm thick with 1.6 mm screws between the standard 2 mm miniplates on both sides. In the last group, we placed Plates 1.4 mm thick with 2.0 mm screws bilaterally on the maxillary zygomatic buttress and piriform rim. Each group was tested in the inferosuperior (IS) and anteroposterior (AP) directions with a servo-hydraulic testing unit. In the IS direction, displacement values were not significantly different up to 80 N, but between 80 and 210 N, those in the 2 x 1.4 mm group were better. In the AP direction, displacement values were not significantly different up to 40 N, but between 40 and 180 N, they were better in the standard with 1.6 x 0.6 mm group and the 2 x 1.4 mm group. When normal biting forces (90- 260 N) in the postoperative period are considered, the greatest resistance to occlusal loads was seen in the 2 x 1.4 mm group. In the others, the biomechanical properties were better in the AP direction. (C) 2016 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.Öğe Comparison of three pain scales after impacted third molar surgery(MOSBY-ELSEVIER, 2011) Isik, Kubilay; Unsal, Alkim; Kalayci, Abdullah; Durmus, ErcanObjective. Recently, a pain assessment scale called "full cup test" (FCT) has been suggested for pain evaluation. It is claimed to be easier to use for the patient, and it allows using parametric tests for statistical analyses. The aim of this study was to evaluate the validity of the FCT in third molar surgery. Study design. The FCT was compared with 2 well accepted pain scales. Forty-eight patients who had fully impacted lower third molars were included. All patients were asked to fill 3 pain scales-visual analog scale (VAS), verbal rating scale (VRS), and FCT-daily during the first postoperative week. Then the scales were collected and data statistically analyzed. Agreement among VAS, VRS, and FCT was evaluated using the Spearman rank coefficient. Results. Correlations among 3 scales were very high and significant (P < .001). Conclusions. The FCT can be used to assess the postoperative pain after third molar surgery. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112:715-718)Öğe Effect of 2 flap designs on postoperative pain and swelling after impacted third molar surgery(ELSEVIER SCIENCE INC, 2013) Dolanmaz, Dogan; Esen, Alparslan; Isik, Kubilay; Candirli, CelalObjective. The aim of this study was to evaluate 2 flap designs (envelope and modified triangular flap) for postoperative pain and swelling after mandibular impacted third molar surgery. Study Design. Thirty patients who had symmetric bilateral fully impacted mandibular third molars were selected. Left teeth were approached with an envelope flap, and right teeth were removed using a modified triangular flap. Postoperative pain and swelling were evaluated until the seventh day by using 2 verbal rating scales. Results. Statistical analyses showed that there were no significant differences between the 2 incision techniques regarding postoperative pain and swelling (P > .05). Conclusions. There is no significant difference between the envelope and modified triangular flap regarding postoperative pain and swelling after impacted third molar surgery.Öğe Histological evaluation of effectiveness of platelet-rich fibrin on healing of sinus membrane perforations: A preclinical animal study(CHURCHILL LIVINGSTONE, 2017) Aricioglu, Ceyhun; Dolanmaz, Dogan; Esen, Alparslan; Isik, Kubilay; Avunduk, Mustafa CihatThe aim of this study was to evaluate the effectiveness of platelet-rich fibrin (PRF) in repairing of Schneiderian membrane perforations in rabbit maxillary sinus. A total of 42 female New Zealand rabbits were randomly divided into two groups. Symmetrical bony defects were created 1 cm in diameter and the sinus membranes were exposed. The Schneiderian membranes were elevated in both sinuses and each membrane was perforated with a 1 cm incision. No treatment was applied to the right perforations in both groups. Left-sided perforations were closed with collagen membrane in the first group and PRF membrane in the other group. Seven animals randomly selected from each group were sacrificed at weeks 1, 2 and 4 in order to be able to examine the amounts of lymphocytes, fibroblasts, veins, and collagen fibers in the area where the membranes were applied. Histological analyses showed that there were no statistically significant differences between the collagen membrane and the PRF membrane in the healing of sinus perforation area. PRF may be considered as an alternative application to collagen membrane in sinus membrane perforations. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.Öğe Histological evaluation of the effects of bioglass, hydroxyapatite, or demineralized freeze-dried bone, grafted alone or as composites, on the healing of tibial defects in rabbits(SAUDI MED J, 2009) Kucukkolbasi, Hasan; Mutlu, Necip; Isik, Kubilay; Celik, Ilhami; Oznurlu, YaseminObjectives: To compare the effectiveness of bioactive glass (BG), natural hydroxyapatite (HA), and demineralized freeze-dried bone (DFDB) in bone defects. Methods: All animal experiments were conducted in Faculty (if Veterinary Medicine, Selcuk University, Konya, Turkey, under the Selcuk University Guidelines for Animal Experimentation, in 2005. Eighteen New Zealand rabbits were used for the experiment. Four cavities were prepared on right and left tibias. The cavities on the right tibia were filled with either BG, HA or DFDB. One cavity was left empty as a control. The cavities on the other tibia] bone were grafted with HA+BG, DFA+DFDB, BG+DFDB and HA+BG+DFDB composites. Histological examinations were performed at first, third, and sixth postoperative months. Results: According to histomorphometric findings, the mixture containing HA+BG+DFDB obtained the best histological results (P<0.05). Conclusion: The composite graft of HA, BG and DFDB is more effective than when used as individual agents.Öğe Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature(SPRINGER HEIDELBERG, 2016) Dolanmaz, Dogan; Esen, Alparslan; Mihmanli, Ahmet; Isik, KubilayWe report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws. Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks. Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage. We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.Öğe A Preferable Technique for Protecting the Inferior Alveolar Nerve: Coronectomy(W B SAUNDERS CO-ELSEVIER INC, 2009) Dolanmaz, Dogan; Yidirim, Gusun; Isik, Kubilay; Kucuk, Korban; Ozturk, AdnanPurpose: The aim of this study was to evaluate the effectiveness of coronectomy for teeth whose root apices are very close to the inferior alveolar canal. Patients and Methods: The 43 patients of this study needed removal of their lower third molar, whose root apices were very close to the inferior alveolar canal. These patients underwent 47 coronectomies. Results: The mean follow-tip period was 9.3 months (range, 1 to 48 months). The mean total amount of root movement was 3.4 mm at 6 months, 3.8 mm at 12 months, and 4.0 mm at 24 months. Conclusions: The technique of coronectomy is defined as removing the crown of a tooth but leaving the roots untouched, so that the possibility of nerve damage is reduced. Coronectomy is a preferable technique for patients who run a risk of injury to the inferior alveolar nerve during third molar surgery. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67:1234-1238, 2009Öğe Proinflammatory cytokines in temporomandibular joint synovial fluid before and after arthrocentesis(MOSBY-ELSEVIER, 2009) Gulen, Huseyin; Ataoglu, Hanife; Haliloglu, Seyfullah; Isik, KubilayObjective. The aim of this study was to evaluate the levels of interleukin (IL)-1 beta, IL-6, IL-8, IL-11, and tumor necrosis factor (TNF)-alpha in temporomandibular joint (TMJ) synovial fluid of the patients with internal derangement before and 2 weeks after arthrocentesis. Study design. Forty TMJs of 35 patients (29 females and 6 males, mean age 22.9 years) were included to the study. TMJs were divided into 2 groups: disc displacement with reduction (Group 1, n = 24) and disc displacement without reduction (Group 2, n = 16). Synovial fluid samples were obtained before and 2 weeks after arthrocentesis. IL-1 beta, IL-6, IL-8, IL-11, and TNF-alpha concentrations were measured by using specific kits. Results. Two weeks after the arthrocentesis procedures, all cytokines were found to be significantly decreased (P < .05) both in Group 1 and Group 2. The difference between 2 groups was insignificant (P > .05). Conclusion. Arthrocentesis is an effective technique for eliminating the studied cytokines from the TMJ synovial fluid. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107:e1-e4)
