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Öğe Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea purpurea and E. pallida(PERGAMON-ELSEVIER SCIENCE LTD, 2009) Orhan, I.; Senol, F. S.; Guelpinar, A. R.; Kartal, M.; Sekeroglu, N.; Deveci, M.; Kan, Y.The dichloromethane, ethyl acetate, ethanol, and aqueous extracts of Cyclotrichium niveum (CN) and Thymus praecox subsp. caucasicus var. caucasicus (TP), Echinacea purpurea (EPU), and E pallida (EPA) along with the essential oils of CN and TP were assessed for their anti-acetylcholinesterase (AChE) and antioxidant activities. AChE inhibition was estimated using spectrophotometric method of Ellman. Antioxidant activity was evaluated by 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging and ferrous ion-chelating power tests. Ferric-reducing antioxidant power (FRAP) of CN and TP were also tested. CN essential oil was found to contain isomenthone (56.21%) and pulegone (19.76%). The ethyl acetate (83.11-87.98%) and dichloromethane (73.45-84.02%) extracts of CN showed the highest AChE inhibition. The ethyl acetate and ethanol extracts of TP exerted significant DPPH scavenger effect. The water extracts of CN and TP and the chloroform extract of the aerial parts of EPU displayed the highest ferrous ion-chelating effect. The leaf and flower essential oils of TP had the best FRAP. (C) 2009 Elsevier Ltd. All rights reserved.Öğe Antimicrobial activity and composition of essential oils of Mentha spicata cultivated under organic farming conditions in Turkey(GEORG THIEME VERLAG KG, 2008) Kartal, M.; Ucan, U. S.; Kan, Y.; Aslan, S.; Atalay, T.[Abstract not Available]Öğe Antimicrobial activity and composition of the essential oils of Echinacea species cultivated under organic farming conditions in Turkey(GEORG THIEME VERLAG KG, 2008) Kan, Y.; Kartal, M.; Ucan, U. S.; Gulpinar, A. R.; Kan, R.[Abstract not Available]Öğe Development and validation of a LC method for the analysis of phenolic acids in Turkish salvia species(SPRINGER HEIDELBERG, 2007) Kan, Y.; Goekbulut, A.; Kartal, M.; Konuklugil, B.; Yilmaz, G.An accurate, simple, reproducible, and sensitive method for determination of rosmarinic, caffeic, cklorogenic, and gallic acids in 12 Salvio species growing naturally in Anatolia, has been developed and validated. The phenolic acids were separated using a mu Bondapack C-18 column by gradient elution with a flow rate of 1.0 mL min(-1), which was adjusted to deliver firstly o-phosphoric acid 0.085% in water, 0.085% in methanol, and 0.085% in 2-propanol (80:10: 10, v/v/v), then decreased gradually (60:20:20, v/v/v) during 20 min with a flow rate of 1.0 mL min(-1). The samples were monitored at 220 nm for gallic acid and 330 nm for rosmarinic, caffeic, and chlorogenic acids using pkoto-diode array detection. The linear range of detection for gallic, chlorogenic, caffeic, and rosmarinic acids were between 0.051-101.4, 0.207-103.6, 0.100-100, and 0.201-100.5 mu g mL(-1), respectively. The linearity, range, peak purity, selectivity, system performance parameters, precision, accuracy, and robustness had also acceptable values. The developed method was applied to the flower, leaf, stem, and root parts of the Salvia species.Öğe Development and Validation of a LC Method for the Analysis of Phenolic Acids in Turkish Salvia Species (vol 66, pg S147, 2007)(SPRINGER HEIDELBERG, 2009) Kan, Y.; Gokbulut, A.; Kartal, M.; Konuklugil, B.; Yilmaz, G.[Abstract not Available]Öğe Effects of different drying methods on caffeic acid derivatives content of Echinacea purpurea cultivated in Turkey(GEORG THIEME VERLAG KG, 2011) Coksari, G.; Gulpinar, A.; Kan, Y.; Kartal, M.[Abstract not Available]Öğe Effects of Echinacea Extract on the Performance, Antibody Titres, and Intestinal Histology of Layer Chicks(TAYLOR & FRANCIS LTD, 2010) Gürbüz, E.; Balevi, T.; Kurtoğlu, V.; Coşkun, B.; Öznurlu, Y.; Kan, Y.; Kartal, M.1. This research was conducted to determine the effect of diet supplementation with Echinacea extract (cichoric acid) on the growth performance, antibody titres and intestinal tissue histology of layer chicks. 2. White, 1-d-old, Hy-Line hybrid chicks (n = 540) were divided into three treatments, each consisting of 6 groups of 30 chicks (n = 180): (1) control; (2) 2 center dot 5 mg/kg cichoric-acid-fed; and (3) 5 mg/kg cichoric-acid-fed. The trial lasted 60 d. 3. While the growth performance of the chicks was depressed between d 1 and 45, it was found to improve between d 45 and 60. 4. Feed consumption was lower in both of the cichoric-acid-fed groups than in the control group between d 1-15 and 15-30, but was higher between d 30 and 45. Overall, mean feed consumption did not differ between the control and cichoric-acid-fed groups during the 60 d study period. 5. During the 60 d evaluation period, live weight gain, feed utilisation rate and final live weight were higher in the control group than in both of the cichoric-acid-fed groups. 6. Antibody titres against infectious bronchitis and infectious bursal disease did not differ between the three groups, but those for Newcastle disease were higher in the 2 center dot 5 mg/kg cichoric-acid-fed group than in the control group after 45 d. 7. Height and width of the jejunal villus and the thickness of the muscle layer were lower in the 5 mg/kg cichoric-acid-fed group than in both the control and the 2 center dot 5 mg/kg cichoric-acid-fed groups. The height of the ileal villus was also lower in the 5 mg/kg cichoric-acid-fed group than in the other two groups. 8. Echinacea extract supplementation for layer chicks appears not to benefit growth performance and intestinal histology during the growing period.Öğe Elemental compositions of Echinacea purpurea, E. pallida radix and herba cultivated in Turkey(GEORG THIEME VERLAG KG, 2011) Kan, Y.; Coksari, G.; Guner, S. T.; Kose, Y. B.; Demirci, F.[Abstract not Available]Öğe Evaluation of in vitro cytotoxic activity of organic and aqueous extracts of Glycyrrhiza iconica(GEORG THIEME VERLAG KG, 2016) Demir, D.; Kan, Y.; Kirmizibekmez, H.[Abstract not Available]Öğe In vitro antiviral assessment against DNA and RNA viruses as well as antibacterial and antifungal profiles of selected Turkish species of the Salvia genus(GEORG THIEME VERLAG KG, 2006) Orhan, I; Ozcelik, B.; Kartal, M.; Karaoglu, T.; Yilmaz, G.; Kan, Y.; Sener, B.[Abstract not Available]Öğe Investigation on Compositions of Seed Oil and Yield of Silymarin of Seeds from Silybum marianum (L.) Gaertn. Cultivated in Konya Ecological Conditions(GEORG THIEME VERLAG KG, 2011) Celik, S.; Kan, Y.; Kartal, M.[Abstract not Available]Öğe LC-MS analysis of alkamides in Echinacea purpurea and Echinacea pallida cultivated in Turkey(GEORG THIEME VERLAG KG, 2007) Kartal, M.; Kan, Y.; Gulpinar, A. R.[Abstract not Available]Öğe Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa(ELSEVIER, 2019) Bardakci, H.; Celep, E.; Gozet, T.; Kan, Y.; Kirmizibekmez, H.This study was designed to comparatively evaluate the phytochemical composition and antioxidant potentials of fruit extracts from five Crataegus taxa (C. monogyna, C. orientalis, C. pontica, C. rhipidophylla and C. turcicus) growing wild in the flora of Turkey. Antioxidant activities of the samples were investigated using DPPH radical scavenging, FRAP, CUPRAC and total antioxidant capacity tests. Total phenol, phenolic acid, flavonoid, and proanthocyanidin contents were measured spectrophotometrically. Additionally, the presence of some phenolic compounds in the extracts was investigated by LC-MS/MS. Furthermore, the extracts used for the antioxidant activity studies were standardized for chlorogenic acid and hyperoside by HPTLC densitometry. Among the tested extracts, C. turcicus contained the highest phenolic (398.48 +/- 0.98 GAE/g extract) and total flavonoid contents (23.87 +/- 2.74 QE/g extract) content while C. monogyna contained by far the highest total proanthocyanidin (175.65 +/- 10.59 EGCG-E/g extract), hyperoside (0.42%) and chlorogenic acid (0.90%) contents. Crataegus monogyna exhibited the highest antioxidant activity in FRAP, CUPRAC, and TOAC tests. Good correlation was found between the phenolic content and antioxidant parameters. This is the first report related with comparison of these five species in respect to phenolic profile and antioxidant activity. (C) 2019 SAAB. Published by Elsevier B.V. All rights reserved.
