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    Activity of essential oils and individual components against acetyl and butyrylcholinesterase
    (WALTER DE GRUYTER GMBH, 2008) Orhan, Ilkay; Kartal, Murat; Kan, Yueksel; Sener, Bilge
    We have tested acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of nineteen essential oils obtained from cultivated plants, namely one from Anethum graveolens L. (organic fertilizer), two from Foeniculum vulgare Mill. collected at fully-mature and flowering stages (organic fertilizer), two from Melissa officinalis L. (cultivated using organic and chemical fertilizers), two from Mentha piperia L. and M. spicata L. (organic fertilizer), two from Lavandula officinalis Chaix ex Villars (Cultivated using organic and chemical fertilizers), two from Ocimum basilicum L. (green and purple-leaf varieties cultivated using only organic fertilizer), four from Origanum onites L., O. vulgare L., O. munitiflorum Hausskn., and O. majorana L. (cultivated using organic fertilizer), two from Salvia sclarea L. (organic and chemical fertilizers), one from S officinalis L. (organic fertilizer), and one from Satureja cuneifolia Ten. (organic fertilizer) by a spectrophotometric 1 mg/ml concentration. In addition, a method of Ellman using ELISA microplate-reader at 1 mg/ml number of single components widely encountered in most of the essential oils [gamma-terpinene, 4-allyl anisole, (-)-carvone, dihydrocarvone. (-)-phencone, cuminyl alcohol, cumol, 4-isopropyl benzaldehyde, trans-anethole, camphene, iso-borneol, (-)-borne0l, L-bornyl acetate. 2-decanol, 2-heptanol, methyl-heptanol, farnesol, nerol, iso-pulegol, 1,8-cineole, citral, citronellal, citronellol, geraniol, linalool, alpha-pinene, beta-pinene, piperitone, iso-menthone. menthofurane, linalyl oxide, linalyl ester, geranyl ester, carvacrol, thymol, menthol, vanilline, and eugenol] was also screened for the same activity in the same manner. Almost all of the essential oils showed a very high inhibitory activity (over 80%) against both enzymes, whereas the single components were not as active as the essential oils.
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    Medicinal Plants with AntiAging Effect Cultivated in Our Country
    (ORTADOGU AD PRES & PUBL CO, 2008) Kan, Yueksel
    Since ancient times the herbal drugs have been used in Turkey for different purposes, such as food, drug, perfumery, and cosmetics. For herbal products, it is necessary to establish good agriculture practice to ensure appropriate and consistent quality of medicinal plant. Because medicinal plants have physiologically strong effects as on human organism, all the steps from plant to drug must be controlled until they reach at consumer. Cultivation conditions such as climate, soil, fertilizer, and irrigation influence the effective compounds such as essential oil, flavonoid, alkaloid, glycoside, and vitamin, In this study, in our country, properties of the medicinal plants cultivated in our country and used for antiaging effects have been investigated.