Yazar "Karabagli, Hakan" seçeneğine göre listele
Listeleniyor 1 - 20 / 27
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe An aggressive parameningeal rhabdomyosarcoma with multiple spinal cord metastases: a case report and review of the literature(SPRINGER, 2017) Yavas, Guler; Karabagli, Pinar; Paksoy, Yahya; Yavas, Cagdas; Karabagli, Hakan; Koksal, YavuzPurpose Spinal cord metastasis from rhabdomyosarcoma (RMS) is extremely rare, with three cases reported to date. Herein, we report an aggressive case of RMS of the infratemporal fossa who which developed spinal cord metastases during treatment. Case presentation A 6-year-old girl presented with an enlarging painless mass around her right ear for 3 months. An enhanced magnetic resonance imaging (MRI) revealed a 5 x x4 x x4.5 5 cm mass on her right infratemporal fossa. A tru-cut biopsy was performed, and histopathologic examination revealed the diagnosis of rhabdomyosarcoma. At the time of the diagnosis, cerebrospinal fluid cytology was negative for malignant cells. The patient underwent induction chemotherapy. There was minimal response to chemotherapy, and the patient underwent curative radiotherapy. However, by 12th fraction of RT, the patient developed a progressive weakness on her lower extremity. Spinal MRI revealed multiple gross masses in different parts of the spinal cord. The local radiotherapy was changed toas craniospinal radiotherapy. However, two 2 weeks after the completion of the RT, the patient developed sepsis and expired because of septic shock. Conclusion Parameningeal RMS is a peculiar subgroup of RMS, which needs an aggressive approach. Despite aggressive approach, meningeal spread is the most important cause of the treatment failure. We should keept in mind that during the treatment, there can be meningeal spread towards to either the brain or spinal cord; therefore, we should follow -up the patients closely from this aspect.Öğe Aggressive rhabdoid meningioma with osseous, papillary and chordoma-like appearance(WILEY, 2014) Karabagli, Pinar; Karabagli, Hakan; Yavas, GulerMeningiomas are the most common primary intracranial tumors. They are usually benign and slowly growing; however, they may show histologically malignant features categorizing them into grade II or III of World Health Organization (WHO) classification. Rhabdoid meningioma (RM) is an uncommon meningioma variant categorized as WHO grade III. The clinical course of RM is determined by local recurrences, invasion of adjacent brain and/or dura, widespread leptomeningeal dissemination, remote metastases and fatal clinical outcome. Herein we report a case with recurrent aggressive left occipital parasagittal region RM in which the patient initially declined radiation treatment. The tumor was resected four times in 5 years. Histopathological examination revealed a rhabdoid meningioma with metaplastic, papillary and chordoid differentiation. Six months after her fourth operation the patient died of progressive disease. RM is a rare subtype of malignant meningioma and the role of different adjuvant therapeutic options are still unknown. Clinical presentation, radiological features and pathologic findings of this uncommon tumor are discussed.Öğe Arachnoid cyst: a further anomaly associated with Kallmann syndrome?(SPRINGER, 2016) Etus, Volkan; Karabagli, Hakan[Abstract not Available]Öğe Benign Malformative Lesion of the Skull: Hamartoma with Ectopic Elements or Choristoma?(DE GRUYTER OPEN LTD, 2017) Meram, Ece; Karabagli, Hakan; Glastonbury, Christine; Tihan, Tarik; Karabagli, PinarHamartoma and choristoma are terms that describe non-neoplastic, mass-forming malformative lesions. Although each lesion has a different composition, they have been used interchangeably in many reports, especially for malformative lesions containing ectopic or heterologous elements. We report a three month-old girl who was brought to the clinic with a mass lesion at the posterior fontanel, composed of predominantly osteo-cartilaginous tissue admixed with skeletal muscle, peripheral nerve tissue, and ganglion. The mass was resected completely. The composition of this benign lesion with ectopic elements was consistent with an osteo-cartilaginous hamartoma. We discuss the biological and clinical aspects such malformative lesions within the skull to highlight the inconsistencies of the nomenclature used in the literature.Öğe Can hypo/hypernatremic conditions be a factor for na ion channel kinetics: model study(Turkish Neurosurgical Soc, 2018) Ayaz, Murat; Karabagli, Hakan; Yanardag, Sirma BasakAIM: Dysnatremic cases are frequently faced in clinical practice. Its macroscopic effects and consequences are well known, but microscopic effects are not well defined. The aim of this study was to reveal the effects of dysnatremia at the cellular level. MATERIAL and METHODS: By using an action potential simulation, the effects of extracellular sodium (Na) concentration on the Na ion channel kinetics were studied. The experimental sets were chosen to mimic hypo/hypernatremic conditions and, in both cases, the degree of the severity was varied. RESULTS: Hyponatremic situations through modifying the axonal Na+ channels kinetics result in the rundown of the sodium current (INa). The degree of the hyponatremia-dependent effect seen in the Na ion channel is severity dependent, which is more effective in the recovery phase of the ion channel. Hypernatremic conditions, on the other hand, have also affected the Na ion channel activity through modifying the kinetics of the channel. Unlike hyponatremia, the effect seen in hypernatremic conditions was through decreasing the response time of the channel. The degree of the significance of the effect seen on the Na ion channel in the case of the hypernatremia was found to be less destructive compared to the hyponatremic condition. CONCLUSION: The Na channels are susceptible to the changes of the extracellular Na concentrations. Thus, the underestimation of hypo/hypernatremic conditions can put patients in danger and close monitoring of serum Na level might be required.Öğe A CASE WITH ABSENCE OF B LYMPHOCYTES(SPRINGER/PLENUM PUBLISHERS, 2014) Ozdemir, Hulya; Artac, Hasibe; Ural, Onur; Karabagli, Hakan; Caliskaner, A. Zafer[Abstract not Available]Öğe Comparison of Local Steroid Injection and Pulsed Radiofrequency Neuromodulation for the Treatment of Mild Idiopathic Carpal Tunnel Syndrome(JOURNAL NEUROLOGICAL SCIENCES, 2016) Suslu, Husnu; Turan Suslu, Hikmet; Guclu, Bulent; Ozdogan, Selcuk; Duzkalir, Ali Haluk; Karabagli, HakanAim: The aim of this study was to compare the effectiveness of local steroid injection and pulsed radiofrequency neuromodulation for the treatment of mild idiopathic carpal tunnel syndrome. Methods: Fifty-nine patients investigated retrospectively. The results of local steroid injection for the treatment of idiopathic carpal tunnel syndrome in 28 patients were compared with pulsed radiofrequency neuromodulation in 31 patients. The visual analogue scale and neuropathic pain scale scores were evaluated before and 1, 3 and 6 months after treatment in both groups. Results: Following the procedure, each patient reported an absence of pain, disappearance or reduction of paraesthesia and improvement in hand function. At 1, 3 and 6 months after the procedure, there was significant improvement in visual analog scale and neuropathic pain scale scores compared to the preprocedure states in both groups. The improvement rates of preprocedure and postprocedure visual analog scale scores and neuropathic pain scale scores were similar for both groups except postprocedure sixth month scores. There was a statistically significant difference in neuropathic pain scale scores at postoperative sixth month between the local steroid injection and pulsed radiofrequency neuromodulation groups so that local steroid injection reported more effective. Conclusion: Local steroid injection gives better long-term results than pulsed radiofrequency neuromodulation for the treatment of idiopathic carpal tunnel syndrome.Öğe Comparison of Spinal and General Anesthesia in Lumbar Disc Surgery(JOURNAL NEUROLOGICAL SCIENCES, 2011) Kara, Inci; Celik, Jale Bengu; Oc, Bahar; Apilliogullari, Seza; Karabagli, HakanAim: The purpose of this study was to compare the perioperative advantage and disadvantage between general (GA) and spinal anesthesia (SA). Material and Methods: Sixty patients (randomize GA, n=30, SA, n=30) undergoing lumbar disc surgery were enrolled. Patients were matched for demographic data, perioperative physiological changes, pain score, amount of blood loss, surgeon 'satisfaction, perioperative complications and length of stay in hospital. Results: Intraoperatively and postoperatively, the incidence of tachycardia and hypertension were more frequent with GA (p<0.05). The surgeon's satisfaction was reported to be higher in the GA group (p<0.05). Anesthetic and operative times were longer for patients in GA group (p<0.05), in whom more nausea, vomiting, pain and greater requirements for antiemetic and pain medication were also during PACU (p<0.05). 24 hours after surgery, PACU time, ambulation of day of surgery, hospital stay, requirement of antiemetic and analgesic medication, pain score, nausea, urinary retention and headache were similar in two groups (p>0.05), however vomiting was more frequent in GA group in this period (p<0.05). Conclusion: For patients undergoing lumbar disc surgery, spinal anesthesia was as safe and effective as general anesthesia. Specific advantages to spinal anesthesia include decreased antiemetic and analgesic medication and reduced overall complication rate.Öğe Controlled Trial of Efficacy of Dexketoprofen in Sciatic Nerve Crush Injury in Rats(JOURNAL NEUROLOGICAL SCIENCES, 2014) Kaptan, Hulagu; Kasimcan, Omur; Ayaz, Murat; Bozdogan, Onder; Karabagli, HakanObject: Local applications of Dexketoprofen trometamol (dex) have been shown to increase in the sciatic nerve functional tests following the nerve injuries. The aim of the current study was to compare the efficacy of dex application for 1 and 5 days following nerve injury rat model. Possible effects of dex were checked by means of the Sciatic Function Index (SFI), Withdrawal of the Reflex Leg (WRL), number of axons, axon diameter, and nerve diameters. Material Methods: The animal crushed model was done through Aesculap -Yasargil aneurysm method on Wistar albino (N=21) right sciatic nerves. In order to achieve desired purpose 3 experimental groups were organized: Group 1: control (injured and no drug); Group2: dexketoprofen 1 days (injured and single dose of drug); Group3: dexketoprofen 5 days (injured and single dose of 5 times drug applications). Injections were done through the tissue expander's injection port with a connecting tube directed at the crush-injured site. Functional recovery of the sciatic nerves was evaluated with the improvement in the SFI values. Additionally, recovery of sensory function was assessed through WRL results and histopathological examination was performed 6 week following the injury. Results: At the end of the experimental periods there was no significant differences were found between the experimental group of animals on the bases of the number of axons, axon diameter, and nerve diameter. Moreover, up 30th day of the experimental period our functional test results have shown that there was no difference between the groups. But following the induction of the injury, the statistical significances were seen on the functional tests. This effect was seen only if the multi-dose application of the dex. Conclusions: This study suggests that; dexketoprofen trometamol of 5 consecutive days, has revealed positive significant changes in the sciatic nerve injury through analgesic effect of it.Öğe Currarino syndrome: report of five consecutive patients(SPRINGER, 2014) Duru, Soner; Karabagli, Hakan; Turkoglu, Erhan; Ersahin, YusufThe Currarino syndrome is regarded as a developmental disorder based on its recognized etiological heterogeneity. This syndrome is thought to result from abnormal separation of the neuroectoderm from the endoderm. Our aim was to report the neurosurgical management of Currarino syndrome in children and adults and to describe what clinician could do if the Currarino triad was suspected. We present five cases of Currarino triad who underwent surgical intervention. All patients had sacral bony deformity, anorectal malformations, and anterior sacral meningocele. A 40-year-old-male had chronic constipation. He was incidentally diagnosed with Currarino syndrome. A 19-year-old-female suffered from a slight weakness in lower extremities and urinary incontinence. Her past medical history was remarkable for anal atresia. The other three cases were children. When an anterior sacral meningocele is encountered, Currarino syndrome should be taken into consideration. Although it is rarity, the Currarino syndrome might be one of the causes of chronic constipation. Endoscopic or endoscope-assisted surgery via a posterior sacral route can be feasible for treatment of some of the patients with anterior sacral meningocele. Anterior meningocele pouch associated with Currarino syndrome will regresses over time following transdural ligation of its neck.Öğe Desmoplastic non-infantile astrocytic tumor with BRAF V600E mutation(SPRINGER JAPAN KK, 2014) Karabagli, Pinar; Karabagli, Hakan; Kose, Dogan; Kocak, Nadir; Etus, Volkan; Koksal, Yavuz[Abstract not Available]Öğe Does shunt selection affect the rate of early shunt complications in neonatal myelomeningocele-associated hydrocephalus? a multi-center study(Turkish Neurosurgical Soc, 2018) Kahilogullari, Gokmen; Etus, Volkan; Morali, Tugba Guler; Karabagli, Hakan; Unlu, AgahanAIM: To evaluate the effect of shunt selection on the rate of shunt revision due to early shunt complications in neonatal myelomeningocele-associated hydrocephalus. MATERIAL and METHODS: The data of 157 neonatal myelomeningocele cases in three pediatric neurosurgery centers (Ankara University, Kocaeli University, Selcuk University) who underwent shunt surgery at the time of myelomeningocele repair between 2000 and 2014 were retrospectively analyzed. Clinical features of the patients, shunt types, and early shunt complications within the first three months were recorded. The patients were classified according to several features of the shunt systems, such as the valve type, valve size/contour and catheter type. RESULTS: Of all patients, 71 (45.2%) underwent early shunt revision surgery due to various complications. Mechanical complications were the most frequent cause of shunt failure, followed by infection. There was no significant difference among the valve types. Also, no significant difference was observed among the catheter types. Only valve contour/size (contoured regular/ultra-small/burr-hole/cylindrical/neonatal) seemed to significantly affect the rate of early complications. The patients with neonatal-design valves or ultrasmall valves had significantly less complications, such as poor wound-healing, wound-dehiscence, cerebrospinal fluid leak or shunt exposure. The infection rate secondary to these complications was found to be lower. CONCLUSION: Myelomeningocele patients with prominent hydrocephalus frequently have a friable skin, due to reduced macrocrania-related subcutaneous tissues. Small-sized (neonatal-design or ultra-small) valves may significantly reduce the early shunt complication rate among this population.Öğe Early endoscopic ventricular irrigation for the treatment of neonatal posthemorrhagic hydrocephalus: a feasible treatment option or not? a multicenter study(Turkish Neurosurgical Soc, 2018) Etus, Volkan; Kahilogullari, Gokmen; Karabagli, Hakan; Unlu, AgahanAIM: Neonatal intraventricular hemorrhage (IVH) usually results in posthemorrhagic hydrocephalus (PHH). This multicenter study describes the approach of early neuroendoscopic ventricular irrigation for the treatment of IVH/PHH and compares the results with the cases that have been initially treated only with conventional temporary cerebrospinal fluid (CSF) diversion techniques. MATERIAL and METHODS: The data of 74 neonatal PHH cases, that have been treated at three pediatric neurosurgery centers, were retrospectively analyzed. 23 neonates with PHH underwent early endoscopic ventricular irrigation (Group-A). 29 neonates were initially treated with conventional methods (Group-B). 22 neonates underwent ventriculosubgaleal shunt placement (Group-C). Complications, shunt dependency rates, incidence of multiloculated hydrocephalus and incidence of CSF infection were evaluated and compared retrospectively. RESULTS: Group-A, Group-B and Group-C cases did not differ significantly regarding gestational age and birth weight. In Group-A, 60.8% of the patients required a later shunt insertion, as compared with 93.1% of the cases in Group-B and 77.2% of the cases in Group-C. Group-A patients were also associated with significantly fewer CSF infections as well as significantly lower incidence for multiloculated hydrocephalus development as compared with Group-B and Group-C. CONCLUSION: Early removal of intraventricular blood degradation products and residual hematoma via neuroendoscopic ventricular irrigation is feasible and safe for the treatment of PHH in neonates with IVH. Neuroendoscopic technique seems to offer significantly lower shunt rates and fewer complications such as infection and development of multiloculated hydrocephalus in those cases.Öğe Headache-like Subarachnoid Hemorrhage After Digital Subtraction Angiography: A Case Report(TURKISH NEUROLOGICAL SOC, 2018) Eren, Fettah; Ekmekci, Ahmet Hakan; Karabagli, Hakan; Ozturk, SerefnurSubarachnoid hemorrhage (SAH) is a clinical condition with acute-onset, sudden, and severe headache. In addition to headache, severe nausea, vomiting, dizziness, confusion, agitation, focal neurologic deficits, and hypertension can be detected. Findings of meningeal irritation may accompany to these clinical features, 6-24 hours after the hemorrhage. Digital subtraction angiography (DSA) is used for surgical or endovascular treatment planning in order to identify vascular abnormalities, in addition to other imaging studies. After DSA, the frequency of all neurologic complications is between 0.2% and 4.5%. Headache may occur after DSA in an average 50% of patients. This rate is especially higher in female patients. Headache types are usually classified as migraine, tension or postoperative atypical headaches The incidence of severe headache after DSA is low. Vascular wall rupture should be considered first in severe headache after the procedure. It should also be kept in mind that after all other secondary causes are excluded; SAH-like headaches after DSA can be detected.Öğe Holospinal epidural abscess in a child patient: magnetic resonance imaging findings(ELSEVIER SCIENCE INC, 2015) Koplay, Mustafa; Sivri, Mesut; Emiroglu, Melike Keser; Guler, Ibrahim; Karabagli, Hakan; Paksoy, Yahya[Abstract not Available]Öğe Improvement of non-syndromic Hearing Loss After Treatment of High Cerebrospinal Fluid Pressure. A Case Report(JOURNAL NEUROLOGICAL SCIENCES, 2011) Karabagli, Hakan; Duru, Soner; Imer, Murat; Apuhan, TayfunWe report a newborn male with hydrocephalus that clinically improved hearing loss after the shunt and also endoscopic procedures. These changes were also documented with audiograms. A newborn 4-month-old male presented with non-syndromic bilateral hearing loss with hydrocephalus. In an attempt to improve his hydrocephalus he underwent two operations; first endoscopic third ventriculostomy, and then ventriculo-peritoneal shunt. After 10 months, his magnetic resonance images displayed double compartment hydrocephalus and shunt malfunction. The otologic work-up revealed sensorineural hearing loss. Therefore, endoscopic the compartments fenestration and catheter placement into the compartments and connection with ventriculo-peritoneal shunt was performed. After the third procedure, he had a significant improvement in intracranial pressure findings and hearing clinically. These changes were documented with audiograms. Non-syndromic hearing loss with hydrocephalus may be treatable by improvement of high cerebrospinal fluid pressure level, if the hearing loss is reversible period. The effect of cerebrospinal pressure levels on intra-cochlear fluid pressure and hearing is briefly discussed.Öğe Incidental Transient Cortical Blindness after Lung Resection(THIEME MEDICAL PUBL INC, 2016) Oncel, Murat; Sunam, Guven Sadi; Varoglu, Asuman Orhan; Karabagli, Hakan; Yildiran, HuseyinTransient vision loss after major surgical procedures is a rare clinical complication. The most common etiologies are cardiac, spinal, head, and neck surgeries. There has been no report on vision loss after lung resection. A 65-year-old man was admitted to our clinic with lung cancer. Resection was performed using right upper lobectomy with no complications. Cortical blindness developed 12 hours later in the postoperative period. Results from magnetic resonance imaging and diffusion-weighted investigations were normal. The neurologic examination was normal. The blood glucose level was 92 mg/dL and blood gas analysis showed a PO2 of 82 mmHg. After 24 hours, the patient began to see and could count fingers, and his vision was fully restored within 72 hours after this point. Autonomic dysfunction due to impaired microvascular structures in diabetes mellitus may induce posterior circulation dysfunction, even when the hemodynamic state is normal in the perioperative period. The physician must keep in mind that vision loss may occur after lung resection due to autonomic dysfunction, especially in older patients with diabetes mellitus.Öğe Influence of Prior Lumbosacral Surgery on The Incidence of Intravascular Injection During Transforaminal Epidural Injections(JOURNAL NEUROLOGICAL SCIENCES, 2015) Suslu, Husnu; Suslu, Hikmet Turan; Tatarli, Necati; Ceylan, Davut; Guclu, Bulent; Karabagli, HakanObjective: Percutaneous lumbar transforaminal epidural steroid injections are frequently used to treat low back pain. However, many reports have indicated that this procedure has a high risk of morbidity. The aim of this study was to determine the difference in the incidence of vascular penetration during lumbosacral transforaminal epidural injections between patients with previous lumbar spinal surgery and patients who did not undergo surgery. Design: This is a prospective clinical study. Methods: In this study, patients who received lumbar transforaminal epidural injections at an outpatient spine center were included and followed. An interventional spine physician observed fluoroscopically guided lumbosacral transforaminal epidural steroid injections under live fluoroscopy and recorded contrast patterns. A total of 296 fluoroscopically guided lumbosacral transforaminal epidural steroid injections under live fluoroscopy in 108 patients were evaluated. Results: The incidence of vascular contrast patterns was observed under live fluoroscopy. Vascular injections were observed in 28 of the 296 injections, for an overall incidence of 9.5%. The incidence of intravascular injections among patients was 40.0% (20/50) in the previously operated group and 13.8% (8/58) in the non-operated group. This difference was statistically significant (p<0.001). A secondary analysis was performed to determine if the other factors affected the success of the procedure or increased the incidence of vascular injections. Conclusion: Our results indicated that previous surgery affected intravascular dissemination and increased the risk of vascular injection. Cohesional area caused by previous surgery complicated the injection. Additionally, fluoroscopy count and operation time were also affected by previous surgery.Öğe Intercostal Schwannoma Developed After Radiotherapy: Case Report(JOURNAL NEUROLOGICAL SCIENCES, 2013) Oncel, Murat; Sunam, Guven Sadi; Karabagli, Pinar; Karabagli, Hakan65 year old woman four years ago underwent mastectomy for left breast cancer patients received radiotherapy later. The patient was admitted our hospital due to complaint of pain in the left side of the surgical incision site. There was mass approximately 2cm in which left hemithorax. Surgical resection was performed and pathological investigation was resulted as schwannoma.Öğe Intracranial metastasis of neuroblastoma: in two different areas at the same time(SPRINGER, 2013) Kose, Dogan; Karabagli, Pinar; Yavas, Guler; Karabagli, Hakan; Koksal, YavuzNeuroblastoma (NB) is the most common extracranial solid malignancy in children. The major cause of death from this cancer is metastasis of tumors, and metastasis can be seen in different areas of the body. Metastasis of NB occurs by hematogenous and lymphatic routes. Generally, brain metastases have been reported in only one area of the brain parenchyma. A 4-year-old male patient was treated in our clinic due to the NB that settled in the intra-abdominal region, but the patient presented with headache and nausea approximately 5 months after completion of the treatment. Whereupon, cranial imaging was performed and two masses were detected in the bilateral frontal lobe, and then the patient underwent surgery. Metastatic NB diagnosis was confirmed histopathologically. The patient's chemotherapy treatment is still ongoing. We report the case of a male patient with two separate metastatic masses in the brain parenchyma, which occurred in two different areas at the same time.
