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    Clinical and Imaging Findings in the Alveolar Echinococcosis
    (BENTHAM SCIENCE PUBL LTD, 2009) Emlik, Dilek; Odev, Kemal; Kiresi, Demet A.; Karakose, Serdar; Gok, Mehmet
    Aim: To review the imaging features of alveolar echinococcosis in eight patients with involvement of different organs. Material and Methods: Ultrasound (US) and computed tomography (CT) examinations were performed in all patients, and magnetic resonance imaging (MRI) and color Doppler ultrasound (CDUS) were performed for two patients. Three patients had involvement of only the liver; two had involvement of lung and liver; one had involvement of only the lung; one had involvement of liver and sternum; and one had lung, liver, and adrenal involvement. The diagnosis was confirmed by histopathologic examination in all patients. Results: The lesions located in the liver were generally seen as heterogeneous hypoechogenic on US, hypodense on CT, and hypointense solid masses on MRI. These masses included necrosis and calcifications. Vascular flow on CDUS and contrast enhancement on CT and MRI were not observed in any of the lesions. On CT, lung lesions were seen as multiple, nodular, well-defined or ill-defined opacities; some had cavitations caused by necrosis. Conclusion: Knowledge of imaging characteristics of alveolar echinococcosis makes it possible to provide an early diagnosis radiologically. In addition, radiologic findings have an important role in the follow-up. Ultrasound, CT, and MRI are complementary methods in the diagnosis of alveolar echinococcosis.
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    The goiter prevalence and urinary iodine levels among adolescents
    (TURKISH J PEDIATRICS, 2011) Kutlu, Ruhusen; Karakose, Serdar; Gungor, Kagan; Kulaksizoglu, Sevsen
    Kutlu R, Karakose S, Gungor K, Kulaksizoglu S. The goiter prevalence and urinary iodine levels among adolescents. Turk J Pediatr 2011; 53: 161-168. Endemic goiter and iodine deficiency are among the worldwide major public health problems of today. We aimed to research the goiter prevalence and the urinary iodine level of school children. In this descriptive study, 1,847 school children in Konya aged between 10 and 18 years were included. Urinary iodine level was measured. The mean value of iodine excretion in urine was 198 +/- 46.61 mu g/L. In 40 students (2.2%), the urinary iodine level was <100 mu g/L. Six of these students (0.3%) had moderate iodine deficiency. Thyroid hyperplasia was found with palpation method in 128 students (6.9%). Ultrasonographically, five female students had solid nodule, and one male student had multiple nodules. In our study, no severe iodine deficiency was found. According to the results of our study, the mandatory iodization program in Konya has been conducted successfully.
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    Mangafodipir trisodium-enhanced magnetic resonance imaging for evaluation of pancreatic mass and mass-like lesions
    (W J G PRESS, 2006) Eser, Gul; Karabacakoglu, Aydin; Karakose, Serdar; Eser, Cengiz; Kayacetin, Ertugrul
    AIM: To investigate the role of mangafodipir trisodium (MnDPDP) in focal pancreatic masses and mass-like lesions by evaluating contrast uptake features of the lesions and pancreatic parenchyma after contrast medium injection. METHODS: A total of 37 patients with pancreatic mass or mass-like lesions were examined by unenhanced and MnDPDP-enhanced magnetic resonance imaging (MRI). RESULTS: MRI was obtained 20-40 min after infusion of MnDPDP and homogeneous contrast enhancement was observed in normal pancreas parenchyma. In patients with atrophic pancreas there was no enhancement in pancreatic parenchyma on MnDPDP-enhanced MRI. In 37 patients with 41 pancreatic masses and mass-like lesions, contrast enhancement was observed at 5 lesions on MnDPDP enhanced MRI. Three of these 5 lesions were focal pancreatitis and the other 2 were adenocarcinoma. No contrast enhancement was determined in 36 pancreatic masses and mass-like lesions in 32 patients. CONCLUSION: MnDPDP contrast-enhanced MRI, especially in cases with no parenchyma atrophy, can distinguish focal pancreatic lesion margins. Information about the function of pancreatic parenchyma can be obtained out of tumor. MnDPDP facilitates staging of pancreatic tumors by detection of metastatic lesions in the liver. In addition, diminished heteregenous uptake of MnDPDP in patients with pancreatitis may be helpful in differential diagnosis. (C) 2006 The WJG Press. All rights reserved.
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    Mesenteric Ischemia: An unusual presentation of fistula between superior mesenteric artery and common hepatic artery
    (BAISHIDENG PUBLISHING GROUP INC, 2004) Kayacetin, Ertugrul; Karakose, Serdar; Karabacakoglu, Aydin; Emlik, Dilek
    Chronic mesenteric ischemia is an uncommon condition associated with a high morbidity and mortality. We reported a 36-year old women with postprandial abdominal pain due to chronic mesenteric ischemia caused by a fistula between superior mesenteric and common hepatic artery.
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    Severe anaphylactic reaction to human insulin in a diabetic patient
    (ELSEVIER SCIENCE INC, 2007) Kaya, Ahmet; Gungor, Kagan; Karakose, Serdar
    A 46-year-old nonatopic woman who had been suffering from type 2 diabetes for 17 years was hospitalized at the Endocrinology Department of Selcuk University due to very high glucose levels after recovery from acute hepatitis A infection. She had never used insulin before. After first subcutaneous dose of human regular insulin, severe local allergic reaction developed. Desensitization to insulin was tried. One day later, ketoacidosis developed. Human regular insulin was again subcutaneously injected to the patient. Severe anaphylactic reaction occurred, and in spite of all the medical attempts to save the patient, she died. (c) 2007 Elsevier Inc. All rights reserved.
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    Three-dimensional MR and axial CT colonography versus conventional colonscopy for detection of colon pathologies
    (BAISHIDENG PUBLISHING GROUP INC, 2006) Haykir, Rahime; Karakose, Serdar; Karabacakoglu, Aydin; Sahin, Mustafa; Kayacetin, Ertugrul
    AIM: To evaluate the sensitivity and specificity of MR colonography (MRC) and CT performance in detecting colon lesions, and to compare their sensitivity and specificity with that of conventional colonoscopy. METHODS: Forty-two patients suspected of having colonic lesions, because of rectal bleeding, positive fecal occult blood test results or altered bowel habits, underwent the examinations. After insertion of a rectal tube, the colon was filled with 1000-1500 mL of a mixture of 9 g/L NaCl solution, 15-20 mL of 0.5 mmol/L gadopentetate dimeglumine and 100 mL of iodinized contrast material. Once colonic distension was achieved, three-dimensional gradient-echo (3D-GRE) sequences for MR colonography and complementary MR images were taken in all cases. Immediately after MR colonography, abdominal CT images were taken by spiral CT in the axial and supine position. Then all patients were examined by conventional colonoscopy (CC). RESULTS: The sensitivity and specificity of MRC for colon pathologies were 96.4% and 100%, respectively. The percentage of correct diagnosis by MRC was 97.6%. The sensitivity and specificity of CT for colon pathologies were 92.8%, 100%, respectively. The percentage of correct diagnosis by CT was 95.2%. CONCLUSION: In detecting colon lesions, MRC achieved a diagnostic accuracy similar to CC. However, MRC is minimally invasive, with no need for sedation or analgesics during investigation. There is a lower percentage of perforation risk, and all colon segments can be evaluated due to multi-sectional imaging availability; intramural, extra-intestinal components of colonic lesions, metastasis and any additional lesions can be evaluated easily. MRC and CT colonography are new radiological techniques that promise to be highly sensitive in the detection of colorectal mass and inflammatory bowel lesions. (c) 2006 The WJG Press. All rights reserved.