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Öğe The Atrial Fibrillation in Turkey: Epidemiologic Registry (AFTER)(VIA MEDICA, 2013) Ertaş, Faruk; Eren, Nihan Kahya; Kaya, Hasan; Arıbaş, Alpay; Acar, Göksel; Kanadaşı, Mehmet; Gedik, SelçukBackground: AFTER (Atrial Fibrillation in Turkey: Epidemiologic Registry) is a prospective, multicenter study designed with the aim of describing the prevalence and epidemiology of AF practice in Turkey. This study aims to evaluate stroke risk in non-valvular atrial fibrillation (AF) and anticoagulant drug utilization within conformity to AF guidelines. Methods: Patients were recruited in 17 referral hospitals reflecting all the population of 7 geographical regions of Turkey. 2242 consecutive patients who had been admitted with AF on ECG were included in the study. 1745 of these patients, who had non-valvular AF, were included in the statistical evaluation. Stroke risk was evaluated with the CHA(2)DS(2)-VASc score. Results: The average age of participants was determined to be 69.2 +/- 11.5 years (56% female). Persistent-permanent AF was found to be the most common type of non-valvular AF (78%). The most common comorbid disorder was hypertension (73%). It was found that oral anticoagulant therapy was used by 40% of all patients, 37% of whom had effective INR (2.0-3.0). Upon multivariate analysis, age was found to be the only independent predictor of stroke among the variables' effects on thromboembolic events that created CHA2DS2-VASc abbreviations (OR 1.026, p < 0.001). Conclusions: These results suggest that stroke risk scores should be thoroughly heeded based on guidelines, and that anticoagulation must be applied according to their guidance.Öğe An epidemiological study to evaluate the use of vitamin K antagonists and new oral anticoagulants among non-valvular atrial fibrillation patients in Turkey- AFTER-2 study design(TURKISH SOC CARDIOLOGY, 2015) Ertas, Faruk; Kaya, Hasan; Yildiz, Abdulkadir; Davutoglu, Vedat; Kiris, Abdulkadir; Dinc, Lale; Kafes, HabibeObjectives: Atrial fibrillation (AF) is one of the most common causes of preventable ischemic stroke and is related to increased cardiovascular morbidity and mortality. There is a lack of data in Turkey on the use of new oral anticoagulants (NOACs), and time in therapeutic INR range (TTR) in vitamin K antagonist users and AF management modality. In this multi-center trial, we aimed to analyze, follow and evaluate the epidemiological data in non-valvular AF patients. Study design: Four thousand one hundred consecutive adult patients from 42 centers with at least one AF attack identified on electrocardiography will be included in the study. Patients with rheumatic mitral valve stenosis and prosthetic valve disease will be excluded from the study. At the end of one year, the patients will be evaluated in terms of major cardiac end points (death, transient ischemic attack, stroke, systemic thromboembolism, major bleeding and hospitalization). Results: First results are expected in June 2015. Data about major cardiovascular end-points will be available in January 2016. Conclusion: The rates and kind of oral anticoagulant use, TTR in vitamin K antagonist users and main management modality applied in non-valvular AF patients will be determined by AFTER-2 study. In addition, the rate of major adverse events (MACEs) and the independent predictors of these MACEs will be detected (AFTER-2 Study ClinicalTrials. gov number, NCT02354456.).Öğe Transmission of Hepatitis C Virus Infection to Spouses of Patients Undergoing Chronic Hemodialysis(Karger, 1999) Akarsu, Ersin; Tonbul, H. Zeki; Selçuk, Yılmaz; Kaya, HasanSexual transmission of HCV is relatively rare [1]. However, that anti-HCV measurements were performed with the first-generation tests in previous years may have led to having less evidence HCV transmitted sexually [2]. On the other hand, the prevalence of HCV infection in HD patients is quite high and the transmission of this infection to the patients is generally by way of blood transfusion and nosocomial [3], and the prevalence of HCV infection in HD patients in Turkey is reported as 49.4% in a multicenter study [4]. In this study, we investigated whether anti-HCV-positive HD patients transmitted this infection to their spouses sexually.Öğe Transmission of Hepatitis C Virus Infection to Spouses of Patients Undergoing Chronic Hemodialysis(Karger, 1999) Akarsu, Ersin; Tonbul, H. Zeki; Selçuk, Yılmaz; Kaya, HasanSexual transmission of HCV is relatively rare [1]. However, that anti-HCV measurements were performed with the first-generation tests in previous years may have led to having less evidence HCV transmitted sexually [2]. On the other hand, the prevalence of HCV infection in HD patients is quite high and the transmission of this infection to the patients is generally by way of blood transfusion and nosocomial [3], and the prevalence of HCV infection in HD patients in Turkey is reported as 49.4% in a multicenter study [4]. In this study, we investigated whether anti-HCV-positive HD patients transmitted this infection to their spouses sexually.Öğe Türk Ceza Kanununda suçu bildirmeme suçları(Selçuk Üniversitesi Sosyal Bilimler Enstitüsü, 2019) Kaya, Hasan; Aksan, MuratCeza doktrininde devletin adli fonksiyonlarının işleyebilmesi için, toplumda bazı kişilerin kamu düzenini bozan haksız eylemlerin işlendiğini öğrendikleri hallerde bu hususları ilgili mercilere bildirmeleri gerektiği anlayışı kabul edilmiştir. Bu anlayış çerçevesinde bu çalışmada 5237 sayılı Türk Ceza Kanunun "Millete ve Devlete Karşı Suçlar ve Son Hükümler" başlıklı Dördüncü Kısmının "Adliyeye Karşı Suçlar" başlıklı ikinci kısmında düzenlenen, "Suçu Bildirmeme" suçu, "Kamu Görevlisinin Suçu Bildirmemesi" suçu ve "Sağlık Mesleği Mensuplarının Suçu Bildirmemesi" suçu konu alınmıştır. Çalışmaya konu suçların unsurları ayrı ayrı incelenmiş olup, ayrıca TCK 278, 279 ve 280'de düzenlenen bu suçlara ilişkin doktrindeki farklı görüşler ile Yargıtay İçtihatları çalışma içeriğinde ele alınmaya çalışılmıştır.
