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Öğe Effect of acute swimming exercise on lactate levels and its relation with zinc in pinealectomized rats(JOHN WILEY & SONS LTD, 2007) Baltaci, Abdulkerim Kasim; Cumraligil, Burhan; Kilic, Mehmet; Kaya, OktayIt is argued that melatonin secreted from the pineal gland regulates the levels of zinc, which is an important trace element. Decreases in zinc levels of pinealectomized rats supports this relationship. There is an increasing amount of evidence suggesting that the pineal gland can have important effects on physical activity. The objective of the present study was to explore the changes in serum lactate levels in pinealectornized rats subjected to acute swimming exercise and its relation with zinc. Forty adult male rats of Spraque Dawley strain were equally allocated to four groups. Group 1: General Control Group. Group 2: Pinealectomized Control Group. Group 3: Swimming Control Group. Group 4: Pinealectomized Swimming Group. Serum zinc, melatonin and lactate levels were determined in the blood samples collected from the animals by a decapitation method. Zinc and melatonin levels were higher in Group I than in Groups 2, 3 and 4 (p < 0.01), higher in Group 3 than in Groups 2 and 4 (p < 0.01) and higher in Group 2 than in Group 4 (p < 0.01). The highest lactate levels were found in Group 4 (p < 0.01). Lactate levels in Group 3 were higher than those in Groups I and 2 (p < 0.01), while the levels in Groups I and 2 did not differ. Pinealectomy results in a significant increase in lactate levels in rats subjected to an acute swimming exercise. This increase in lactate levels may be associated with the decrease observed in zinc levels after pinealectomy. Copyright (C) 2006 John Wiley & Sons, Ltd.Öğe Effect of Melatonin Supplementation on Plasma Glucose and Liver Glycogen Levels in Rats Subjected to Acute Swimming Exercise(UNIV KARACHI, 2010) Kaya, Oktay; Kılıç, Mehmet; Çelik, İlhami; Baltacı, Abdulkerim Kasım; Moğulkoç, RasimThe aim of the present study is to examine how melatonin supplementation affects plasma glucose and liver glycogen levels in rats subjected to acute swimming exercise. Spraque-Dawley species thirty adult male rats were allocated to 3 groups with equal number of animals: general control group which was not subjected to any procedure (Group 1), the group subjected to a 30-minute acute swimming exercise (Group 2), and the group subjected to a 30-minute acute swimming exercise after intraperitoneal (i.p.) melatonin supplementation (3 mg/kg/day) for 4 weeks (Group 3). Blood samples collected from the experimental animals by decapitation method were analyzed in terms of plasma glucose, and glycogen levels were determined in liver tissue samples by histological method. The highest plasma glucose levels were obtained in group 2 (p<0,05). Plasma glucose levels in groups 1 and 3 were not different. Mean liver glycogen level in group 3 was significantly higher than those in the other groups (p<0,01), while there was no significant difference between group 1 and group 2 in terms of this parameter. Results of the study demonstrate that melatonin supplementation can have a protective effect on liver glycogen reserves in rats subjected to acute swimming exercise.Öğe Recovering of Ni, Co and Cu from Divrigi Iron Plant tailings by sulphuric acid oxygen pressure leaching(2006) Canbazoğlu, Mehmet; Kaya, Oktay; Akdemir, Ünal; İnan, Aslı; Aydoğan, SalihTurkish Iron and Steel Company at its Divrigi concentrator plant produces magnetite concentrate for sintering using dry and wet magnetic separation. Nearly 750.000 tons of tailings are sent to tailings dam from Divrigi concentrator every year. These tailings contain 0.11 % Cu, 0.145 % Co, 0.35 % Ni, 0.25 g/t Au and 2.2 g/t Ag. The mineralogical composition of these tailings is complex and the minerals of the important metals are present as oxide and sulphides showing fine-grained structure. In this study, the recovery of these metals as Cu, Co and Ni was investigated, using oxidative sulphuric acid pressure leaching. The investigated parameters were leaching time (1 to 8 h), leaching pH (0.5 to 2), leaching temperature (110 °C to 180 °C) and partial oxygen pressure (1 to 6 bar). Under the optimum experimental conditions that were 4 h of leaching, 0.5 pH, temperature of 110 °C and oxygen pressure of 4 bar, the obtained recoveries were 64.10% Ni, 65.01% Co and 76.40% Cu.Öğe Zinc supplementation in rats subjected to acute swimming exercise: Its effect on testosterone levels and relation with lactate(MAGHIRA & MAAS PUBLICATIONS, 2006) Kaya, Oktay; Gokdemir, Kadir; Kilic, Mehmet; Baltaci, Abdulkerim KasimOBJECTIVE: There is fairly scarce information about the effects of zinc, an essential trace element, on performance. Studies concerned with the relation between zinc and exercise mostly concentrate on the distribution of this element in the body in response to exercise. The objective of the present study is to explore how zinc supplementation affects testosterone levels and its relation with lactate in rats subjected to acute swimming exercise. MATERIALS AND METHODS: Thirty adult male rats of Spraque-Dawley species were equally allocated to 3 groups. Group 1: Control. Group 2: Group subjected to 30-minute acute swimming exercise. Group 3: Group supplemented with intraperitoneal (i.p.) zinc (3mg/kgday) for 4 weeks and subjected to 30-minute swimming exercise. Blood samples collected from all experimental animals by decapitation method were analyzed to determine free and total testosterone and lactate levels in the plasma. RESULTS: Group 3 had the highest free and total testosterone levels, followed by Group 1 and Group 2. The highest lactate levels were found in Group 2 and the levels in Group 3 were higher than those in Group 1. CONCLUSION: Results of the study demonstrate that zinc supplementation leads to a significant increase in testosterone levels and a significant decrease in lactate levels. In conclusion, physiological doses of zinc supplementation can be useful for performance.