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Öğe Colitis cystica profunda simulating rectal carcinoma(ACTA MEDICAL BELGICA, 2005) Kayacetin, E; Kayacetin, SLocalized colitis cystica profunda is a rare, benign disease of the lower gastro-intestinal tract, usually presenting as a rectal mass and characterized microscopically by the presence of mucus-filled cysts in the submucosa. Knowledge of this particular pathological entity is important as it can mimic a well differentiated adenocarcinoma of the rectum and therefore could lead to unnecessary surgical resection. We present a case of colitis cystica profunda misdiagnosed as adenocarcinoma based on their similar clinical picture and histological features.Öğe Gastric emptying in subclinical hypothyroidism(LIPPINCOTT WILLIAMS & WILKINS, 2005) Sari, O; Kisakol, G; Kayacetin, E; Kaya, AThe aim of this study is to investigate solid-phase gastric emptying in patients with subclinical hypotbyroidism and to compare it with healthy subjects. Twenty patients with a recently established diagnosis of subclinical hypothyroidism and 10 age-matched healthy subjects participated in this study. Gastric emptying half-time was calculated with solid food labeled with 250 mu Ci Tc-99m-sulfur colloid. There was no difference between serum free T-3 and T-4 values in both groups. Serum thyroid-stimulating hormone level was significantly higher in the subclinical hypothyroid group than in controls. Gastric emptying half-time was 123.94 +/- 18.58 minutes in the subclinical hypothyroid group and 101.80 +/- 25.56 minutes in the control group. These gastric emptying half-times were not different (P = 0.455). We suggest that in subclinical hypothyroidism, gastric emptying of solids is similar to that in age-matched healthy control subjects.Öğe Hydatid cyst of the liver causing a cavernous transformation in the portal vein and complicated by intrabiliary and intraperitoneal rupture(BLACKWELL PUBLISHING ASIA, 2004) Kayacetin, E; Hidayetoglu, T[Abstract not Available]Öğe Overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis with unusual initial presentation as fulminant hepatic failure(PACINI EDITORE, 2004) Kayacetin, E; Koklu, S; Temucin, TAutoimmune hepatitis and primary biliary cirrhosis are generally easy to discriminate on the basis of clinical, laboratory, and histological findings. The presence of anti-mitocondrial antibodies seropositivity and cholestatic clinical, laboratory, and/or histological features in patients with autoimmune hepatitis indicates the overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis. Fulminant hepatic failure is an unusual initial form of presentation of autoimmune hepatitis and primary biliary cirrhosis overlap syndrome. We report the case of a 50-year-old woman with autoimmune hepatitis and primary biliary cirrhosis overlap syndrome who presented with fulminant hepatic failure. Fulminant hepatic failure has a high mortality rate and may require liver transplant. Our patient revealed a good response to corticosteroid and ursodeoxycholic acid therapy. It is important to identify and distinguish autoimmune hepatitis and variant syndromes from other forms of liver disease because of response to corticosteroid therapy. (C) 2004 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.Öğe Portal and splenic hemodynamics in cirrhotic patients: relationship between esophageal variceal bleeding and the severity of hepatic failure(SPRINGER JAPAN KK, 2004) Kayacetin, E; Efe, D; Dogan, CBackground The relationship between portal and splenic vein hemodynamics, liver function, and esophageal variceal bleeding in patients with cirrhosis remains unclear. The aim of the present study was to investigate quantitative Doppler parameters of splanchnic hemodynamics in cirrhotic patients and to determine the value of the Doppler parameters in predicting esophageal variceal bleeding. Methods. With the help of pulsed Doppler ultrasonography, we investigated portal and splenic hemodynamics in 18 healthy controls and in 45 patients with liver cirrhosis, in whom the relationship of splenic hemodynamics with esophageal variceal bleeding and the grade of cirrhosis was examined. Results. Portal flow velocity was decreased in cirrhotic patients with Child's C cirrhosis, as compared to those with Child's A cirrhosis (P < 0.001). The portal blood flow volume in Child's C cirrhosis were also significantly low compared to patients with Child's A and Child's B cirrhosis (P < 0.001 and P < 0.05, respectively). There was a significant increase in the portal vein congestion index and splenic vein congestion index in patients with Child's C cirrhosis as compared to patients with Child's A cirrhosis (P < 0.001). Among cirrhotic patients, the group with esophageal variceal bleeding had significantly greater splenic blood flow volume and splenic vein congestion index (P < 0.001). Patients with ascites had significantly lower portal flow velocity (P < 0.001) and higher portal vein congestion index and splenic vein congestion index (P = 0.003 and P = 0.05, respectively) as compared to those without ascites. Conclusions. In this report we have shown that the decrease in blood flow and increased congestion indexes in the portal vein and splenic vein are related to the impairment of liver function in cirrhotic patients; these indexes may be valuable factors for predicting esophageal variceal bleeding.
