Yazar "Keles, Bahar" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Evaluation of HLA-A, -B, -Cw, and -DRB1 alleles frequency in Turkish patients with nasal polyposis(SAGE PUBLICATIONS LTD, 2008) Keles, Bahar; Cora, Tuelin; Acar, Hasan; Arbag, Hamdi; Inan, Ziya; Ozturk, Kayhan; Ozer, BedriOBJECTIVE: To evaluate whether there is a relationship between HLA-A, -B, -Cw, and -DRB1 alleles and developing nasal polyposis (NP). STUDY DESIGN: Data from 66 patients with NP were compared with data from 100 healthy randomly selected controls. Asthma, ASA (acetylsalicylic acid) triad, polyp score, and previous sinonasal surgery were also recorded. SUBJECTS AND METHODS: Genotyping of the HLA-A, -B, -Cw, and -DRB1 alleles were performed with polymerase chain reaction (PCR) with the sequence-specific primer (SSP) method. Data were analyzed by using a Pearson chi(2) test. RESULTS: The HLA-B*07 and -Cw*12 alleles were found to be significantly higher in the NP patients compared with the control group, whereas the HLA-B*57 and HLA-Cw*04 alleles were significantly lower (P < 0.05). The HLA-A*24, HLA-Cw*12, and HLA-DRB1*04 alleles were determined to be significantly higher in the NP patients with asthma and ASA triad (P < 0.05). CONCLUSIONS: Our results show that some of the HLA alleles seem to be associated with the genetic susceptibility to develop NP in the Turkish population. (C) 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.Öğe The morphometric development of the fetal larynx during the fetal period(ELSEVIER IRELAND LTD, 2008) Cicekdbasi, Aynur Emine; Keles, Bahar; Uyar, MehmetObjective: The aim of the present study was to investigate morphometric growth patterns of the cartilaginous components and vocal cords in human fetal larynx. Methods: This study was performed in the Anatomy Department of Meram Medicine Faculty in 2007. The fetuses were obtained from the Gynaecology Department of the Meram Medicine Faculty of Selcuk University, and Dr. Faruk Sukan Maternity Hospital (Konya, Turkey). Forty spontaneousty aborted fetuses (25 mates and 15 females) without detectable malformations were evaluated. The dimensions of the larynx and its cartilaginous components were measured and the relationship between the obtained data was statistically assessed with Student's t-test. Results: Correlations were found between the cartilaginous components, size of the larynx, and gestational age. No gender differences were identified. The anatomical variations in the epiglottis cartilage dimensions and types were found in 15% of cases. The foramen thyroideum was observed in 12.5% of cases. Conclusion: The data of this study may contribute to the knowledge of the fetal larynx regarding laryngomalacia. (C) 2008 Elsevier Ireland Ltd. All rights reserved.Öğe Transmastoid Decompression of Labyrinthine-Meatal Segment of the Facial Nerve: A Comparative Radio-Anatomic Study(AVES, 2009) Keles, Bahar; Emlik, Dilek; Uyar, Yavuz; Cicekcibasi, Aynur Emine; Ozturk, KayhanObjective: To evaluate the routes for approaching to labyrinthine-meatal segment of the facial nerve (FN) via transmastoid approach by drilling the ampullar ends of the lateral semicircular canal (LSC). Materials and Methods: Ten temporal bones of adult cadavers underwent high-resolution computed tomography (HRCT). Among them in 6 temporal bones the FN was decompressed under operating microscope via transmastoid approach by drilling the ampullar ends of the LSC. Within the remaining four of temporal bones the ampullary ends of the LSC were preserved. All temporal bones were re-evaluated by HRCT scans following the dissection. Distances between labyrinthine-meatal segment and surrounding anatomical landmarks were measured through the HRCT scans. Results: The mean distances from labyrinthine-meatal segment to the midpoint of the basal turn of the cochlea, LSC and vestibule were 9.5 +/- 0.6 mm (range 8.1-10.4), 10.1 +/- 0.2 mm (range 8.5-11.9 mm), 2.6 +/- 0.4 mm (range 1.9-3.2 mm), respectively. The mean distance of remaining bony part of fallopian canal near the meatus was determined as 0.57 +/- 0.3 mm in the temporal bones drilled from the ampullary ends of the LSC and 2.07 +/- 0.5 mm in the temporal bones preserved from ampullary ends of the LSC. This difference was significant (p<0.05). Conclusions: The results showed that the labyrinthine-meatal segment of the FN could be adequately accessed via transmastoid approach by skletonizing the ampullary end of the LSC. This approach may be used as an alternative technique in the decompression of labyrinthine-meatal segment of the FN.Öğe Tympanoplasty in pediatric patients(ELSEVIER IRELAND LTD, 2006) Uyar, Yavuz; Keles, Bahar; Koc, Sema; Oeztuerk, Kayhan; Arbag, HamdiObjective: The aim of this study is to analyze the clinical features and follow-up of a series of pediatric patients with chronic otitis media undergoing tymponaplasty surgery and to identify the effect of the factors on the course. Methods: Forty-one children (mean age 15.1 +/- 2.62 years, range from 8 to 16 years) who had undergone tympanoplasty with or without ossicular reconstruction were evaluated. Age, gender, size and site of perforation, status of operated ear (dry/ discharging), status of the contralateral ear, underlying cause of the perforations, surgical technique, preoperative and postoperative hearing levels, average postoperative follow-up time, and postoperative complications were recorded. Results: Myringoplasty in 28 patients (68.3%), incus interposition in 7 patients (17.1%), partial ossicular replacement prostheses in 4 patients (9.7%) and total ossicular replacement prostheses in 2 patients (4.9%) were performed. In the 37 (90.2%) of patients, intact graft was determined during postoperative follow-up. Surgical success including intact graft and postoperative air-bone gap of less than 25 dB were obtained in 34 (82.9%) cases. Conclusions: The present study suggested that tympanoplasty was a quite successful method in the appropriate pediatric patients between the ages of 8 and 16 years. In the preoperative evaluation for surgery success, some factors, such as dry middle ear, healthy contralateral ear and concordant to postoperative care should be considered. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
