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Öğe Effect of acute swimming exercise on lactate levels and its relation with zinc in pinealectomized rats(JOHN WILEY & SONS LTD, 2007) Baltaci, Abdulkerim Kasim; Cumraligil, Burhan; Kilic, Mehmet; Kaya, OktayIt is argued that melatonin secreted from the pineal gland regulates the levels of zinc, which is an important trace element. Decreases in zinc levels of pinealectomized rats supports this relationship. There is an increasing amount of evidence suggesting that the pineal gland can have important effects on physical activity. The objective of the present study was to explore the changes in serum lactate levels in pinealectornized rats subjected to acute swimming exercise and its relation with zinc. Forty adult male rats of Spraque Dawley strain were equally allocated to four groups. Group 1: General Control Group. Group 2: Pinealectomized Control Group. Group 3: Swimming Control Group. Group 4: Pinealectomized Swimming Group. Serum zinc, melatonin and lactate levels were determined in the blood samples collected from the animals by a decapitation method. Zinc and melatonin levels were higher in Group I than in Groups 2, 3 and 4 (p < 0.01), higher in Group 3 than in Groups 2 and 4 (p < 0.01) and higher in Group 2 than in Group 4 (p < 0.01). The highest lactate levels were found in Group 4 (p < 0.01). Lactate levels in Group 3 were higher than those in Groups I and 2 (p < 0.01), while the levels in Groups I and 2 did not differ. Pinealectomy results in a significant increase in lactate levels in rats subjected to an acute swimming exercise. This increase in lactate levels may be associated with the decrease observed in zinc levels after pinealectomy. Copyright (C) 2006 John Wiley & Sons, Ltd.Öğe Effect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oral zinc(MAGHIRA & MAAS PUBLICATIONS, 2007) Kilic, MehmetOBJECTIVE: The aim of this study was to determine how exercise affects thyroid hormones and testosterone levels in sedentary men receiving oral zinc for 4 weeks. METHODS: The study included 10 volunteers (mean age, 19.47 +/- 1.7 years) who did not exercise. All subjects received supplements of oral zinc sulfate (3 mg/kg/day) for 4 weeks and their normal diets. The thyroid hormone and testosterone levels of all subjects were determined at rest and after bicycle exercise before and after zinc supplementation. RESULTS: TT3, TT4, FT3, and total and free testosterone levels decreased after exercise compared to resting levels before supplementation (p<0.01). Both the resting and fatigue hormone values were higher after 4 weeks of supplementation than the resting and fatigue values before supplementation (p<0.05). CONCLUSION: The results indicate that exercise decreases thyroid hormones and testosterone in sedentary men; however, zinc supplementation prevents this decrease. Administration of a physiologic dose of zinc can be beneficial to performance.Öğe Priapism as Presenting Manifestation of Germ Cell Tumor in a Child(AKAD DOKTORLAR YAYINEVI, 2011) Ozbek, Orhan; Koksal, Yavuz; Koc, Osman; Karagol, Cuneyt; Ozbek, Seda; Kilic, MehmetPriapism, defined as prolonged and persistent erection of the penis without sexual stimulation, is rarely seen in children. We report a 2-year-old boy who was admitted with priapism with a history of the perineal trauma. Doppler ultrasonography revealed signs of high-flow priapism. Magnetic resonance imaging revealed an intrapelvic mass beside the root of the penis. The serum alpha-fetoProtein level was 54.600 ng/ml (Normal range: 0-9 ng/ml). Tru-cut biopsy was performed and endo-dermal sinus tumor was diagnosed. At the fourth day of chemotherapy, the penis became progressively less turgid and soft. After the first cycle chemotherapy, priapism had completely resolved.Öğe Zinc supplementation in rats subjected to acute swimming exercise: Its effect on testosterone levels and relation with lactate(MAGHIRA & MAAS PUBLICATIONS, 2006) Kaya, Oktay; Gokdemir, Kadir; Kilic, Mehmet; Baltaci, Abdulkerim KasimOBJECTIVE: There is fairly scarce information about the effects of zinc, an essential trace element, on performance. Studies concerned with the relation between zinc and exercise mostly concentrate on the distribution of this element in the body in response to exercise. The objective of the present study is to explore how zinc supplementation affects testosterone levels and its relation with lactate in rats subjected to acute swimming exercise. MATERIALS AND METHODS: Thirty adult male rats of Spraque-Dawley species were equally allocated to 3 groups. Group 1: Control. Group 2: Group subjected to 30-minute acute swimming exercise. Group 3: Group supplemented with intraperitoneal (i.p.) zinc (3mg/kgday) for 4 weeks and subjected to 30-minute swimming exercise. Blood samples collected from all experimental animals by decapitation method were analyzed to determine free and total testosterone and lactate levels in the plasma. RESULTS: Group 3 had the highest free and total testosterone levels, followed by Group 1 and Group 2. The highest lactate levels were found in Group 2 and the levels in Group 3 were higher than those in Group 1. CONCLUSION: Results of the study demonstrate that zinc supplementation leads to a significant increase in testosterone levels and a significant decrease in lactate levels. In conclusion, physiological doses of zinc supplementation can be useful for performance.
