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Öğe Comparison of CT virtual cystoscopy of the contrast material-filled bladder with conventional cystoscopy in the diagnosis of bladder tumours(W B SAUNDERS CO LTD, 2009) Kivrak, A. S.; Kiresi, D.; Emlik, D.; Odev, K.; Kilinc, M.AIM: To investigate the value of virtual cystoscopy using contrast material to fill the bladder during routine abdominopelvic computed tomography (CT) examinations for the detection of bladder tumours. MATERIALS AND METHODS: Thirty-three consecutive patients (25 men and eight women; are range 51-82 years; mean age +/- SD, 65 +/- 7 years) who had painless macroscopic haematuria and were suspected to have bladder neoplasms were prospectively evaluated with virtual cystoscopy. After intravenous injection of contrast medium, the contrast material-filled bladders were examined with single-detector helical CT with 2-mm section thicknesses. Source CT data were transferred to a workstation for interactive navigation using surface rendering. ALL the patients also underwent conventional cystoscopy. RESULTS: The results of virtual cystoscopy were compared with the findings from the conventional cystoscopy. Seventy-one of 78 bladder tumours detected with conventional cystoscopy in 28 patients were also shown on virtual images. The bladders of five patients appeared normal on both conventional cystoscopy and virtual cystoscopy. On virtual cystoscopy, seven of the 12 lesions that were <= 5 mm in diameter could be identified. The following statistical values for the identification of bladder lesions using virtual cystoscopy were calculated: sensitivity 94%, specificity 90%, positive predictive value 87%, negative predictive value 93%, and accuracy 93%. CONCLUSION: CT virtual cystoscopy is a noninvasive technique that can be used successfully for detection of bladder tumours >5 mm in selected cases during daily routine abdominopelvic work. (C) 2008 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.Öğe Comparison of semen profile and frequency of chromosome aneuploidies in sperm nuclei of patients with varicocele before and after varicocelectomy(WILEY, 2009) Acar, H.; Kilinc, M.; Guven, S.; Yurdakul, T.; Celik, R.Semen profile and meiotic segregation products are important for assessing aneuploidy risk and risk of resulting infertility. To determine the effect of varicocelectomy on semen profile and aneuploidy frequency, we investigated semen profile and aneuploidy frequency of selected chromosomes in patients with varicocele before and after varicocelectomy. Chromosomal aneuploidy for selected chromosomes was evaluated using chromosome-specific DNA fluorescence in situ hybridisation (FISH) probes. There was a significant difference in the level of normal sperm morphology before and after varicocelectomy (P > 0.007). There were no significant differences in aneuploidy frequency of chromosomes 1, 16, 17 and 18 in sperm nuclei obtained from patients before varicocelectomy compared with 6-7 months after varicocelectomy (P > 0.05), although FISH analysis with chromosomes 17 and 18 combination showed a higher aneuploidy frequency before varicocelectomy than after varicocelectomy (7.81 +/- 9.67 versus 4.03 +/- 1.46 respectively). In conclusion, varicocele seems to affect the semen profile but minimally affects aneuploidy frequency. Varicocelectomy demonstrates a repairing effect on the semen profile and contributes to a slight decrease in aneuploidy frequency in some but not all chromosomes.Öğe EFFECTS OF UROLOGY SPECIALISTS AND RESIDENTS OF DIFFERENT LEVELS OF EXPERIENCE TO PNL RESULTS(ELSEVIER SCIENCE BV, 2011) Guven, S.; Ozturk, A.; Gurbuz, R.; Goger, E.; Kaynar, M.; Ardic, M.; Kilinc, M.[Abstract not Available]Öğe Evaluation of Renal Function Using DTPA Scintigraphy and Frequency Determination of Ptotic Kidney in Patients with History of Preeclampsia(SPRINGER, 2005) Tastekin, G.; Gencturk, A.; Kilinc, M.[Abstract not Available]Öğe Giant prostatic hyperplasia: Case report(SPRINGER, 2006) Yilmaz, K.; Istanbulluoglu, O.; Guven, S.; Kilinc, M.The giant hyperplasia of the prostate is extremely rare pathology of prostate gland. Here, we report the successful removal of the 9th heaviest prostate ever reported in the literature.Öğe Is methylenetetrahydrofolate reductase (MTHFR) gene A1298C polymorphism related with varicocele risk?(WILEY, 2015) Ucar, V. B.; Nami, B.; Acar, H.; Kilinc, M.Varicocele is one of the main reasons for male infertility the exact aetiology of which remains unclear. Methylenetetrahydrofolate reductase (MTHFR) is important for DNA synthesis and methylation, which has a key role during spermatogenesis. Numerous literature suggests that the MTHFR polymorphism may be genetic risk factors for male infertility. In this study, we evaluated C677T and A1298CMTHFR gene polymorphism frequency in patients with varicocele and normal men. A total of 107 varicocele patients and 109 fertile healthy individuals were included. Genotyping of the MTHFR gene in C677T and A1298C base pairs carried out by using real-time PCR technique and afterwards, the statistical analysis accomplished. There is a statistical difference for the frequency of 1298AA genotype in patients with varicocele compared with normal controls (P=0.0051, OR=2.2750). Instead, subsequently, 1298/A allel frequency in patient group was significantly higher in comparison with control group (P=0.0174). According to our results, 1298AA genotype in MTHFR gene raises the risk of varicocele approximately 2.3 times more compared with men carrying other genotypes. The results show that genetic factors have an important role in the molecular basis of varicocele.Öğe Partial priapism secondary to tamsulosin: a case report and review of the literature(WILEY, 2009) Kilinc, M.; Piskin, M.; Guven, S.; Gurbuz, R.; Odev, K.; Kaynar, M.Partial priapism is also called partial segmental thrombosis of the corpus cavernosum. It is a rare pathology, and its aetiology, physiopathology and treatment are still not completely understood. To our knowledge, partial priapism due to alpha blockers has not been reported previously in the literature. In this study, a successfully treated case of partial priapism occurring after the usage of alpha blocker is presented and discussed in light of the related literature.Öğe TOTALLY TUBELESS PERCUTANEOUS NEPHROLITHOTOMY: IS IT SAFE AND EFFECTIVE IN PRESCHOOL CHILDREN? -- 2(MARY ANN LIEBERT INC, 2010) Guven, S.; Ozturk, A.; Kilinc, M.; Topbas, E.; Piskin, M.; Arslan, M.[Abstract not Available]
