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Öğe Application of first-pass contrast bolus tracking sequence for the assessment of morphology and flow dynamics in cardiac MRI(AVES, 2013) Paksoy, Yahya; Ozbek, Orhan; Gumus, Serter; Koc, Osman; Nayman, Alaaddin; Kerimoglu, UlkuPURPOSE There are two well-known indications for first-pass perfusion in the literature. First is the evaluation of Myocardial ischemia, and the other is the evaluation of tumor vascularity. Our aim was to assess the value of a first-pass Contrast bolus tracking sequence (FPCBTS) for cases unrelated to these pathologies. MATERIALS AND METHODS A total of 35 patients (age range, 1 day to 66 years; mean age, 10.4 +/- 19.2 years; median age, 4.5 months) with suspected congenital (n=31) and acquired (n=4) heart and great vessel disease Were included in the study. All the patients underwent cardiac magnetic resonance imaging (MRI) and FPCBTS, and 20 patients underwent contrast enhanced magnetic resonance angiography (CE-MRA). We used cardiac MRI and CE-MRA for anatomic evaluation and FPCBTS for dynamic flow evaluation. RESULTS Truncus arteriosus, double outlet right ventricle, tetralogy of Fallot; corrected transposition of great arteries, atrial and ventricular septal defect, aortic rupture, cardiac hydatid cyst, tricuspid atresia, anomalous pulmonary venous return; and interrupted aorta were detected using the technique described here. Septal defects in six patients arid atrial aneurysm in two patients were excluded. The shunt gap and flow direction of the septal defects, a ruptured Wall in a dissected aorta, a hydatid cyst, and the atrial relationship in two cases with paracardiac masses Were diagnosed easily using this dynamic evaluation technique. CONCLUSION FPCBTS Can be performed in addition to cardiac MRI and CE-MRA to reveal flow dynamics and morphology.Öğe Bronchocele: Demonstration By 3D Volume Rendering Imaging with Multidetector Computed Tomography: Case Report(ORTADOGU AD PRES & PUBL CO, 2011) Sakarya, Mehmet Emin; Ceran, Sami; Koc, Osman; Ozbek, Orhan; Karabekmez, Leman G.; Odev, KemalCongenital bronchial atresia (CBA) is a rare congenital abnormality of the lung. It results from a congenital focal obliteration of a proximal segmental or sub-segmental bronchus with normal development of distal structures. Because of proksimal bronchial stenosis, the distal bronchi became filled with mucus and form a bronchocele. Three dimensional (3D) volume rendering (VR) imaging was performed with 64-slice multidetector computed tomography (MDCT) equipment in a patient with CBA and bronchocele. 3D VR images clearly revealed branching nonenhancing tubular structure and the adjacent lung with features of air trapping. A diagnosis of bronchocele was made radiologically. We report a case of bronchocele documented by 3D image reconstruction and VR images using 64-slice MDCT. In this article we report that, the radiologic findings of the broncocele can be shown more clearly with 3D VR technique than standan CT imaging.Öğe Comparison of Thermographic Imaging and Other Diagnostic Techniques in Diagnosis of Cattle with Laminitis(UNIV FED RIO GRANDE DO SUL, 2018) Arican, Mustafa; Hatipoglu, Fatih; Erol, Hanifi; Kanat, Ozgur; Yavuz, Orhan; Parlak, Kurtulus; Koc, OsmanBackground: Lameness results in major economic losses on dairy farms. The proportion of lameness in cows are between 4-55%, the origin of 90% lameness are caused by foot diseases. Hoof abnormalities such as laminitis are major contributors to lameness. Aim of the study, compared with thermographic imaging (IRT) and radiographic, magnetic resonans (MR), computer tomography (CT), histopathological analysis on the diagnosis of laminitis. Materials, Methods & Results: Preliminary, the animals (20 Holstein-Fresian) were selected by lameness examination for evaluation of the for any obvious signs of disease. The animals were examined when rising and walking of the free stalls. Walking was very painful and clinical symptoms of general distress become present for laminitic group. The cows were scored on a 1 to 5 scale for their locomotion (1 = normal locomotion; 5 = severely lame). Thermographic examinations were performed the all animals after the routine clinical examination methods. The infrared images were taken from the dorsal view of all hooves to monitor the temperature of coronary band. All images were scanned using a hand-held portable infrared camera (Wahl, Thermal Imager HSI3000 Series), which was calibrated to ambient temperature and absorptive conditions. Incentives radiological examinations, dorso-palmar and latero-medial shooting was done for using of (Regius Model 110 Konica, Minolta) 70 kV and 30 mAs for each claws. MRI images of all isolated digits were performed at the Department of Radiology, by using Siemens Symphony Erlangen, Germany. Continuous series of transversal, sagital and dorsoplantar scan were obtained from all digit. Computer tomography (CT), isolated digits were performed at the Imaging Department of Radiology, by using Siemens Symphony Erlangen, Germany. CT scanner was used to obtain contiguous slices from the region of the proximal sesamoid bones to the toe. Anterior side (laminar and perilaminar tissues) of the claws was uncovered with electric wheel. Tissue samples were taken 10% buffered formaldehyde solution after establishing a routine laboratory procedure following the prepared paraffin blocks 5 micrometers thick sections with hematoxylineosin dye method according to the staining. It was finally examined by light microscopy. The computer soft ware of the infrared thermal camera showed increased local temperature, by 0.5-1.5 degrees C, between the normal and suspected regions for laminitic cases. Clinically, animals suspected of laminitis were showed general stiffness, lameness during walking difficulty. Examination of the claws was demonstrated of rings and plump appearance was evident in paries ungulae. The main damage was seen during trimming of the sole from no hemorrhages or discoloration of control group. The transversal MRI images provided excellent depictions of anatomical structures when compared to their corresponding pictures. Identifiable anatomic structure was labeled on the line drawings of the limb sections and on the corresponding CT images. Twenty out of 30 claws (65%) were shown laminitis statistical with histopathological examination. In histopathological examination; mononuclear cells and neutrophil granulocytes infilrations and edema, haemorrhagia, mild hyperemia in the lamellar region was remarkable in laminitic cases. Discussion: As a results, thermographic examination may have potential as a detection tool for laminitis. MR transversal images provided excellent depiction of anatomical structures and many biometric research in the bovine hoof can be easily investigated. The usefulness of IRT, MRI, CT in evaluating laminitis in the acute patient remains stil open. The use of diagnostic techniques during the initial active phase of laminitis as a means to increase the understanding of the disease and also serves as a justification for the development of an experiment involving live cows induces laminitis.Öğe Complementary Use of NBCA with the Amplatzer Vascular Plug for Embolization of a High-Flow Traumatic Hepatic Arteriovenous Fistula(SPRINGER, 2009) Koc, Osman; Cil, Barbaros Erhan; Peynircioglu, Bora; Emlik, Dilek; Ozbek, Orhan[Abstract not Available]Öğe Differential diagnosis of dumbbell lesions associated with spinal neural foraminal widening: Imaging features(ELSEVIER IRELAND LTD, 2009) Kivrak, Ali Sami; Koc, Osman; Emlik, Dilek; Kiresi, Demet; Odev, Kemal; Kalkan, ErdalComputed tomography (CT) and magnetic resonance imaging (MRI) reliably demonstrate typical features of schwannomas or neurofibromas in the vast majority of dumbbell lesions responsible for neural foraminal widening. However, a large variety of unusual lesions which are causes of neural foraminal widening can also be encountered in the spinal neural foramen. Radiologic findings can be helpful in differential diagnosis of lesions of spinal neural foramen including neoplastic lesions such as benign/malign peripheral nerve sheath tumors (PNSTs), solitary bone plasmacytoma (SBP), chondroid chordoma, superior sulcus tumor, metastasis and non-neoplastic lesions such as infectious process (tuberculosis, hydatid cyst), aneurysmal bone cyst (ABC), synovial cyst, traumatic pseudomeningocele, arachnoid cyst, vertebral artery tortuosity. In this article, we discuss CT and MRI findings of dumbbell lesions which are causes of neural foraminal widening. (C) 2008 Elsevier Ireland Ltd. All rights reserved.Öğe Dural Carotico-Cavernous Fistula: Pre and Postembolization Appearances of Bone-Subtracted CT Angiography(TURKISH NEUROSURGICAL SOC, 2013) Koc, Osman; Genc, Emine; Ozturk, Banu; Genc, Bulent Oguz; Keskin, Fatih; Ozbek, OrhanDigital subtraction angiography (DSA) is the best method of evaluating carotid cavernous fistulas (CCF). DSA, however, has the disadvantage of being an invasive procedure. Computerized tomography (CT) angiography which is noninvasive, have been shown to provide more information about the size and location of fistulas. As a new method, Bone-Subtraction CT Angiography (BSCTA), than conventional CT angiography, is a method that improves the detection and interpretation of vascular lesions near to the cavernous segment of carotid artery. In this case report, we report a case of a dural carotico-cavernous fistula (CCF), appearances of pre and postembolization BSCTA images, confirmed by on DSA. As far as we know, CCF demonstrated by BSCTA has not been reported yet.Öğe Dural Carotico-Cavernous Fistula: Pre and Postembolization Appearances of Bone-Subtracted CT Angiography(2013) Koc, Osman; Genc, Emine; Ozturk, Banu; Genc, Bulent Oguz; Keskın, Fatıh; Ozbek, OrhanDij ital subtraksiyon anj iyografi (DSA) karotiko-kavernöz fistülü (KKF) değerlendirmede en iyi metodtur. Ancak DSA invaziv bir yöntemdir. Noninvaziv bir yöntem olan Bilgisayarlı tomografi (BT) anj iyografi fistül lokalizasyonu ve büyüklüğünü gösterebilir. Yeni bir yöntem olan Kemik baskılı BT anj iyografi (KBBTA) özellikle karotid arterin kavernöz segment lezyonlarının saptanmasında ve yorumlanmasında konvansiyonel BT anj iyografiye göre daha değerli bilgiler vermektedir. Bu olgu sunumunda, tanısı DSA ile doğrulanmış KKF olgusunun pre ve postembolizasyon görüntülerini sunduk. Bizim bilgilerimize göre KBBTA ile tanısı konulan KKF olgusu bildirilmemiştir.Öğe Endovascular Management of Massive Gastrointestinal Bleeding Associated with Polyarteritis Nodosa(ELSEVIER SCIENCE INC, 2009) Koc, Osman; Ozbek, Orhan; Gumus, Serter; Demir, Ali[Abstract not Available]Öğe Epstein-Barr virus encephalitis: findings of MRI, MRS, diffusion and perfusion(TURKISH J PEDIATRICS, 2011) Ozbek, Orhan; Koc, Osman; Paksoy, Yahya; Aydin, Kursad; Nayman, AlaaddinOzbek O, Koc O, Paksoy Y, Aydin K, Nayman A. Epstein-Barr virus encephalitis: findings of MRI, MRS, diffusion and perfusion. Turk j Pediatr 2011; 53: 680-683 Epstein-Barr virus is an infection that is known as infectious mononucleosis. Even though the central nervous system is not a primary region of involvement of this disease, neurological complications are reported rarely. In this case report, we evaluated a 15-month-old male who presented to the pediatric neurology clinic due to high fever and a neurologic attack. His serological tests and radiological examinations (magnetic resonance imaging (MRI), MR spectroscopy (MRS), diffusion-weighted imaging (DWI) and MR perfusion) were consistent with Epstein-Barr virus encephalitis, which is a very rare complication of infectious mononucleosis. Additionally, we discuss the MRI, MRS, DWI and MR perfusion findings of our case, which were different from other cases reported in the literature.Öğe Priapism as Presenting Manifestation of Germ Cell Tumor in a Child(AKAD DOKTORLAR YAYINEVI, 2011) Ozbek, Orhan; Koksal, Yavuz; Koc, Osman; Karagol, Cuneyt; Ozbek, Seda; Kilic, MehmetPriapism, defined as prolonged and persistent erection of the penis without sexual stimulation, is rarely seen in children. We report a 2-year-old boy who was admitted with priapism with a history of the perineal trauma. Doppler ultrasonography revealed signs of high-flow priapism. Magnetic resonance imaging revealed an intrapelvic mass beside the root of the penis. The serum alpha-fetoProtein level was 54.600 ng/ml (Normal range: 0-9 ng/ml). Tru-cut biopsy was performed and endo-dermal sinus tumor was diagnosed. At the fourth day of chemotherapy, the penis became progressively less turgid and soft. After the first cycle chemotherapy, priapism had completely resolved.Öğe Radiofrequency ablation of a rare pathology: vertebral intraosseous lipoma(ELSEVIER SCIENCE INC, 2016) Ozbek, Orhan; Keskin, Fatih; Kaya, Hasan Emin; Guler, Ibrahim; Nayman, Alaaddin; Koc, Osman[Abstract not Available]Öğe Radiofrequency ablation of phalangeal osteoid osteoma: technical challenges encountered in small bones(TURKISH JOINT DISEASES FOUNDATION, 2011) Ozbek, Orhan; Nayman, Alaaddin; Koc, Osman; Kucukapan, Ahmet; Ozbek, Seda; Kerimoglu, UlkuOsteoid osteoma, a benign bone tumor, is characterized by a generally less than 1 cm nidus surrounded by a zone of reactive sclerosis. It is frequently located in the femur and tibia; on the other hand in up to 5% of cases it may be presented in upper extremities. In previous years, its treatment was usually open surgery with en-bloc resection or curettage of the tumor. Various minimal invasive percutaneous treatments including radiofrequency ablation became popular in last years. In this report, the difficulties encountered during radiofrequency ablation treatment in small bones is described in a 19-year-old female case of osteoid osteoma.Öğe Radiologic findings of a traumatic urethral diverticulum with stones in an infertile male patient(TURKISH SOC RADIOLOGY, 2011) Ozbek, Orhan; Piskin, Mesut; Koc, Osman; Kadiyoran, Cengiz; Ozbek, Seda; Odev, KemalUrethral diverticulum is rarely encountered in male patients. Although postmicturition dribble, pain and infection are usually present, infertility is rarely reported in urethral diverticulum. We present a case with urethral diverticulum associated with infertility, which was diagnosed radiologically.Öğe Renal artery embolization in severe nephrotic syndrome(WILEY-BLACKWELL, 2016) Solak, Yalcin; Koc, Osman; Ucar, Ramazan; Ozbek, Orhan; Ergenc, Hasan; Gaipov, Abduzhappar; Turk, SuleymanIntroduction Severe nephrotic syndrome is associated with increased morbidity and mortality. Renal artery embolization (RAE) has been used in a number of renal diseases such as renal tumors, arteriovenous fistulas etc. However, data regarding benefits of RAE in patients with symptomatic severe proteinuria is limited. We decided to evaluate role of RAE in the setting of severe symptomatic nephrotic syndrome. Methods Eight patients who had undergone transcatheter renal artery embolization with polyvinyl alcohol (PVA) were included. Clinico-demographic characteristics as well as baseline laboratory data including level of proteinuria, serum albumin, C-reactive protein and LDL cholesterol levels were recorded for each patient. After RAE, outpatient clinic control laboratory values were also assessed. Findings All patients except one underwent bilateral RAE (four simultaneous or three sequential). Two patients experienced postembolization syndrome characterized by flank pain, fever, and leukocytosis, which was self-limited and responded to analgesics in all patients. There was no technical complications associated with RAE procedure. All patients became anuric except one. Serum albumin levels increased and serum LDL-cholesterol levels decreased considerably in treated patients. Discussion Renal artery embolization with the purpose of amelioration in nephrotic syndrome complications was effective and free of major technical complications in our patients.Öğe Role of diffusion weighted MR in the discrimination diagnosis of the cystic and/or necrotic head and neck lesions(ELSEVIER IRELAND LTD, 2007) Koc, Osman; Paksoy, Yahya; Erayman, Ibrahim; Kivrak, Ali Sami; Arbag, HamdiPurpose: The purpose was to determine whether the diffusion weighted imaging (DWI) was able to differentiate necrotic tumor or metastatic lesions from infected necrotic lesions such as abscesses and necrotic lymphadenitis in the neck. Materials and methods: DWI was performed on 37 consecutive patients with 85 head and neck necrotic and cystic lesions. The lesions were classified into four categories: metastatic lymph node involvement including lymphoma, necrotic tumor, abscesses and necrotic lymphadenitis. Each lesion was histopathologically studied and proved. Results: In 12 patients, there were 35 necrotic lymphadenitis (necrotic tuberculosis lymphadenitis, n = 18; necrotic nonspecific suppurative lymphadenitis, n = 17). Of the 15 necrotic metastatic nodes, 11 lesions were lymphomatous involvement and 4 lesions were other tumor involvement. Other 11 patients have abscesses. Thirteen primary tumoral necrotic lesions arose in the neck of nine patients. All of the abscesses and necrotic lympadenitis showed hyperintensity on DWI, in contrast to necrotic tumor and necrotic nodal metastasis that showed hypointensity on DWI. DWI successfully differentiated metastatic nodes and necrotic tumors from necrotic lymphadenitis and abscesses. Conclusion: DWI may be supportive for differentiating necrotic tumor lesions such as necrotic tumor and metastatic necrotic nodes from the infective necrotic lesions such as necrotic lymphadenitis and abscesses in the head and neck. (c) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe Short-Term Effects of Ankaferd Hemostat for Renal Artery Embolization: An Experimental Study(SPRINGER, 2013) Ozbek, Orhan; Acar, Kadir; Koc, Osman; Saritas, Kadir; Toy, Hatice; Solak, Yalcin; Ozbek, SedaRenal artery embolization (RAE) is a minimally invasive therapeutic technique that is utilized in a number of disorders. Ankaferd is a novel hemostatic agent with a new mechanism of action independent of clotting factors. We used Ankaferd for RAE in a sheep model. Seven adult female sheep were included in the study. Selective renal arteriogram using 5-F diagnostic catheter was performed to make sure that each kidney was fed by a single renal artery and the animal had normal renal vasculature. Coaxial 2.7-F microcatheter was advanced to the distal main renal artery. Under fluoroscopic guidance, 2 mL of Ankaferd mixed with 2 mL of nonionic iodinated contrast agent was slowly injected. Fluoroscopy was used to observe the deceleration of flow and stagnation. Control renal angiograms were performed just after embolization. After the procedure, the animals were observed for 1 day and then sacrificed with intravenous sodium thiopental. The technical success was observed in seven of the seven animals.. After embolization procedure, none of the animals died or experienced a major systemic adverse event. On macroscopic examination of the embolized kidneys, thrombus at the level of main renal artery formed after Ankaferd embolization was more compact compared with the thrombi that was not Ankaferd-associated, which was observed elsewhere. Microscopically, majority of the renal tubular cells (80-90 %) were necrotic, and there was epithelial cell damage in a small portion of the cells (10-20 %). RAE was safe and effective in the short-term with Ankaferd in studied animals. Further studies should be conducted to better delineate the embolizing potential of this novel hemostatic agent.Öğe Splenic artery embolization with Ankaferd blood stopper in a sheep model(AVES, 2016) Koc, Osman; Acar, Kadir; Ozbek, Orhan; Guler, Ibrahim; Saritas, Kadir; Erdem, Tuba Bera; Solak, YalcinPURPOSE Splenic artery embolization is a minimally invasive therapeutic procedure utilized in a number of disorders. Ankaferd blood stopper (ABS) is a novel hemostatic agent with a new mechanism of action independent of clotting factors. We aimed to investigate the safety and efficiency of ABS for splenic artery embolization in a sheep model. METHODS Seven adult female sheep were included in the study. Selective celiac angiography was performed using a 5F diagnostic catheter and then a 2.7F hydrophilic coating microcatheter was advanced coaxially to the distal part of the main splenic artery. Under fluoroscopic guidance, 6 mL mixture composed of half-and-half ABS and contrast agent was slowly injected. Fluoroscopy was used to observe the deceleration and stagnation of the flow. Control celiac angiograms were obtained immediately after the embolization. After the procedure, the animals were observed for one day and then sacrificed with intravenous sodium thiopental. RESULTS Technical success rate was 100%. None of the animals died or experienced a major systemic adverse event during the procedure. All of the spleens appeared dark on macroscopic examination due to excessive thrombosis. Microscopically, the majority of the splenic sinusoids (90%-95%) were necrotic. CONCLUSION In our study, splenic artery embolization by ABS was found to be safe and effective in the short-term. Further studies are needed to better understand the embolizing potential of this novel hemostatic agent.
