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Öğe Anti-tumor necrosis factor-alpha therapy is associated with less frequent mood and anxiety disorders in patients with rheumatoid arthritis(WILEY-BLACKWELL PUBLISHING, INC, 2009) Uguz, Faruk; Akman, Cemal; Kucuksarac, Seher; Tufekci, OsmanThe purpose of the present study was to examine the current prevalence of mood and anxiety disorders, and factors related to mood and anxiety disorders in patients with rheumatoid arthritis (RA). The study sample included 83 consecutive patients with RA who were admitted to a rheumatology outpatient clinic. Diagnoses of psychiatric disorders were determined using the Structured Clinical Interview for DSM-IV (SCID-I). To assess physical disability and disease activity, the Health Assessment Questionnaire and the Disease Activity Score, respectively, were used. The prevalence of any mood or any anxiety disorder was 43.4%. The two most common psychiatric diagnoses were major depression (21.7%) and generalized anxiety disorder (16.9%). Mood and anxiety disorders were unrelated to sociodemographic features, disease-related factors, and medications for RA except anti-tumor necrosis factor-alpha (TNF-alpha). These disorders, however, were identified less frequently in patients with RA receiving anti-TNF-alpha drugs compared to patients who did not receive such medications. Patients with RA frequently have mood and anxiety disorders, and anti-TNF-alpha drugs may be useful for the mental status of these patients.Öğe EFFECTS OF EXERGAMES ON BALANCE, FUNCTIONAL MOBILITY, AND QUALITY OF LIFE OF GERIATRICS VERSUS HOME EXERCISE PROGRAMME: RANDOMIZED CONTROLLED STUDY(NATL INST PUBLIC HEALTH, 2015) Karahan, Ali Yavuz; Tok, Fatih; Taskin, Halil; Kucuksarac, Seher; Basaran, Aynur; Yildirim, PelinAim: To compare the effects of exergames (EGs) using the Xbox KinectTM device and home exercise (HE) on balance, functional mobility, and quality of life of individuals aged 65 years or older. Method: One hundred participants who met the inclusion criteria were randomized to the EG or HE group. The EG group took part in a 6-week programme using the Xbox360KinectTM device, and the HE group took part in a 6-week balance exercise programme at home 5 days a week. The Berg Balance Scale (BBS) was used to assess balance, the Timed Up and Go (TUG) test was used to evaluate functional walking, and the Short Form 36 (SF-36) was used to assess quality of life. Results: Forty-eight participants in the EG group and 42 participants in the HE group completed the study. The groups were similar in terms of age, sex, and pretreatment values of BBS, TUG, and SF-36. Although the BBS scores of both groups improved significantly (all p < 0.05), the post-treatment scores of the EG group were better than those of the HE group. The TUG scores improved only in the EG group (p <0.05). The increase in the BBS scores and decrease in the TUG test scores were significant only in the EG group (all p <0.05). A significant improvement was also observed in the quality of life parameters of physical functioning, social role functioning, physical role restriction, general health perceptions, and physical component scores in the post-exercise evaluations of the EG group. The participants commented that they found the EG programme very entertaining. Conclusion: The EG can be considered a safe, entertaining and sustainable alternative to HE programmes, and it may have positive effects on balance, functional walking and quality of life in geriatric subjects.Öğe The impact of psychiatric disorders on quality of life in patients with rheumatoid arthritis(CUMHURIYET UNIV TIP FAK PSIKIYATRI ANABILIM DALI, 2009) Uguz, Faruk; Kucuksarac, Seher; Akman, Cemal; Tufekci, OsmanObjective: In recent years, the relationship between quality of life (QoL) and mental disorders in subjects with medical illnesses has been acquiring more importance. The present study was designed to examine the effects of psychiatric disorders on QoL in patients with rheumatoid arthritis (RA). Methods: The study was carried out among patients with RA who admitted to rheumatology outpatient clinic of department of physical medicine and rehabilitation of an university hospital. The study sample included 30 RA outpatients with axis I psychiatric disorder, 30 RA outpatients and 30 healthy subjects without any axis I psychiatric disorder. The psychiatric disorders were determined by means of the Structured Clinical Interview for DSM-IV. To determine the participants' QoL levels, we used the World Health Organization QoL Assessment-Brief (WHOQOL-BREF). Disease activity for RA was assessed with the Disease Activity Score. Results: Most of patients with RA were women, and they were mostly taking medications such as non-steroid anti-inflammatory drugs, corticosteroids, and metothrexate. Of RA patients with psychiatric disorders, 50% (15) had only depressive disorders, and 20% (6) had only anxiety disorders. The study groups had similar features with respect to age, sex, educational level, and marital status. There was no significant difference for treatments, disease duration and disease activity between RA patients with and without axis I psychiatric disorder. The QoL levels of all domains were lowest in RA patients with a psychiatric diagnosis. In addition, RA patients without psychiatric disorder had significantly lower scores of WHOQOL-BREF compared to healthy controls. Conclusion: The study results suggest that patients with RA have poorer QoL levels, and that psychiatric disorders appear to be a considerable factor affecting QoL of patients with RA. (Anatolian Journal of Psychiatry 2009; 10: 94-99)Öğe Treatment of Periodontoid Pannus With Infliximab in a Patient With Rheumatoid Arthritis(LIPPINCOTT WILLIAMS & WILKINS, 2009) Salli, Ali; Sahin, Nilay; Paksoy, Yahya; Kucuksarac, Seher; Ugurlu, Hatice[Abstract not Available]