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Öğe Investigation of effect of vitamin E on serum lipids(BLACKWELL PUBLISHING, 2007) Taspinar, M.; Kurban, S.; Mehmetoglu, I.[Abstract not Available]Öğe Investigation of serum nitric oxide, total antioxidant activity and oxidized LDL levels of obese subjects and healthy controls(WILEY, 2006) Yerlikaya, H. F.; Mehmetoglu, I.; Kurban, S.; Yilmaz, G.[Abstract not Available]Öğe Ischaemia-modified albumin levels in newborn jaundice before and after phototherapy(WILEY, 2011) Erdem, S. S.; Kurban, S.; Altunhan, H.; Annagur, A.; Ors, R.; Yerlikaya, F. H.; Gokce, R.The aim of our study was to assess the effect of phototherapy (PT) on ischaemia-modified albumin (IMA) and malondialdehyde (MDA) levels in hyperbilirubinemic full-term newborns. The study was performed on 36 full-term infants exposed to PT. The babies were aged 3 to 13 days. IMA and MDA levels of the babies were determined before and after PT, by a colorimetric assay. IMA levels before and after PT were found as 0.424 +/- 0.290 and 0.531 +/- 0.262 absorbance units, respectively. Although IMA levels after PT were slightly higher, the difference was not statistically significant (p > 0.131). MDA levels before and after PT were found as 8.4 +/- 1.8 mu mol/l and 9.4 +/- 1.5 mu mol/l, respectively. Serum MDA concentrations were significantly higher after PT than before PT (p < 0.000). In previous studies, conflicting findings have been reported about the effect of PT on oxidant and antioxidant systems. However, we have found no study investigating IMA levels in hyperbilirubinaemia in newborns before and after PT. Our results shows that PT does not affect IMA levels significantly. IMA increases as a result of oxidative stress. We believe that the lack of significant difference between our IMA levels before and after PT may resulted from hyperbilirubinaemia, which has antioxidant effect. Copyright (C) 2011 John Wiley & Sons, Ltd.Öğe Nitric oxide levels and eNOS gene polymorphism in patients with coronary artery disease documented by angiography(BLACKWELL PUBLISHING, 2007) Yılmaz, G.; Mehmetoğlu, I.; Kurban, S.; Acar, H.[Abstract not Available]Öğe Osteoprotegerin and RANKL levels in multiple sclerosis(BLACKWELL PUBLISHING, 2007) Kurban, S.; Akpinar, Z.; Mehmetoglu, I.[Abstract not Available]Öğe Plasma myristic acid levels of obese and non-obese Turkish subjects(WILEY-BLACKWELL, 2011) Yerlikaya, H. F.; Mehmetoglu, I.; Kurban, S.[Abstract not Available]Öğe Pre-operative Atorvastatin Therapy to Decrease the Systemic Inflammatory Response after Coronary Artery Bypass Grafting(SAGE PUBLICATIONS LTD, 2008) Dereli, Y.; Ege, E.; Kurban, S.; Narin, C.; Sarigul, A.; Yeniterzi, M.The effect of pre-operative atorvastatin on systemic inflammatory response syndrome (SIRS), often seen after coronary artery bypass grafting (CABG) was evaluated in 40 patients undergoing elective CABG. Patients were divided into two groups: group I (pre-operative LDL cholesterol 100 mg/dl; n = 20) received 20 mg/day atorvastatin for at least 15 days pre-operatively; group II (pre-operative LDL cholesterol < 100 mg/dl; n = 20) did not receive antihyperlipidaemic agents. All patients underwent CABG with cardiopulmonary bypass. Blood samples were taken pre-operatively and 24 h post-operatively. There were no significant differences between the two groups in terms of demographic, pre-operative or operative parameters. At 24 h post-operatively, median high-sensitivity C-reactive protein and mean interleukin-6 levels were significantly lower in group I compared with group II. There were no other significant differences in postoperative parameters between the two groups, except for duration of stay in the intensive care unit, which was shorter in group I patients. In conclusion, pre-operative atorvastatin treatment in patients undergoing elective CABG decreased inflammation parameters and could be effective in preventing SIRS.