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Öğe Association of "Controlling Nutritional Status Index'' and "Prognostic Nutritional Index'' with intensive care unit survival in elderly patients(SPRINGER, 2016) Kos, M.; Titiz, H.; Onec, B.; Soysal, T.; Kutlucan, A.; Emen, S. Sahiner; Kutlucan, L.Objectives: Providing proper nutritional support for the intensive care unit (ICU) patients is only possible with assessment of malnutrition. In this study, we aimed to evaluate associations between nutritional indexes which were developed to assess malnutrition using blood parameters, and survival among elderly patients in the ICU. Patients and methods: Patients older than 65 years of age and monitored in the ICU, were retrospectively screened with nutritional indexes in order to assess the nutritional status. Each patient was evaluated with both "Controlling Nutritional Status Index'' (CONUT) which includes albumin, total cholesterol, total lymphocyte counts, and "Prognostic Nutritional Index'' (PNI) which includes only albumin beside total lymphocyte count. Results: Two hundred twenty five patients were enrolled in this study. Median age was 79 (range: 65100). One hundred and eleven (49.3%) patients died during intensive care follow-up. CONUT and PNI scores displayed significant differences between patients who died and who were discharged (P = 0.02 and P = 0.03, respectively). Kaplan-Meier analysis revealed that high CONUT (>= 5) and low PNI (<40) scores were associated with intensive care unit survival but statistical significance was not provided for PNI (P = 0.04 and P = 0.06, respectively). Conclusion: Both CONUT and PNI indexes seems associated with survival but only CONUT score provides statistically significant prognostic information and may serve as a cost-effective nutritional assessment tool in elderly patients. Because this association did not retain its significance on multivariate analysis, the validity of this index in elderly patients should be further evaluated by prospective studies including larger samples. (C) 2015 Elsevier Masson SAS and European Union Geriatric Medicine Society. All rights reserved.Öğe BLASTIC INFILTRATION OF THE CENTRAL NERVOUS SYSTEM IN A PATIENT WITH CHRONIC MYELOID LEUKEMIA(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Dagli, M.; Kutlucan, A.; Kutlucan, L.; Basturk, A.; Ugurluoglu, C.; Sozen, M.; Turkay, K.[Abstract not Available]Öğe CAN LEUKOCYTE SUBGROUPS OF CRITICAL PATIENTS BE AN INDICATOR FOR MORTALITY, DURATION OF HOSPITALISATION AND DEVELOPMENT OF HOSPITAL INFECTION?(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Kutlucan, L.; Kutlucan, A.; Basturk, A.; Basaran, B.; Kozanhan, B.; Gur, M.; Senocak, E.[Abstract not Available]Öğe A CASE OF NEUTROPENIA DUE TO ACUTE EXPOSURE WITH ALUMINUM PHOSPHIDE(PERGAMON-ELSEVIER SCIENCE LTD, 2014) Dagli, M.; Basturk, A.; Kutlucan, L.; Copur, B.; Kutlucan, A.; Colkesen, F.[Abstract not Available]Öğe CHEMOTHERAPY IMPROVED COAGULATION DISORDER IN A PATIENT WITH MULTIPLE MYELOMA(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Fidan, K.; Kutlucan, A.; Dağlı, M.; Baştürk, A.; Sözen, Mehmet; Abuşoğlu, Sedat; Kutlucan, L.[Abstract not Available]Öğe CLINICAL IMPORTANCE OF B2 GLYCOPROTEIN I ANTIBODIES IN BCR-ABL NEGATIVE MYELOPROLIFERATIVE NEOPLASMS(FERRATA STORTI FOUNDATION, 2016) Kocak, M. Z.; Dagli, M.; Kutlucan, A.; Basturk, A.; Unlu, A.; Acar, H.; Kutlucan, L.[Abstract not Available]Öğe COINCIDENCE OF AUTUIMMUNE HEMOLYTIC ANEMIA AND AUTOIMMUNE HEPATITIS(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Kutlucan, A.; Dagli, M.; Kutlucan, L.; Ermis, F.; Basturk, A.; Ugurluoglu, C.; Sozen, M.[Abstract not Available]Öğe COMPARISON OF PULSE WITH HIGH DOSE STEROID TREATMENT IN PATIENTS WITH IMMUNE THROMBOCYTOPENIA(PERGAMON-ELSEVIER SCIENCE LTD, 2014) Dagli, M.; Kutlucan, L.; Basturk, A.; Kutlucan, A.; Copur, B.[Abstract not Available]Öğe THE EFFECT OF ANEMIA AND RED CELL TRANSFUSIONS ON MORTALITY IN YOUNG AND ELDERLY INTENSIVE CARE PATIENTS WITH NOSOCOMIAL INFECTION(PERGAMON-ELSEVIER SCIENCE LTD, 2014) Kutlucan, L.; Kutlucan, A.; Kandis, H.; Titiz, H.; Senocak, E.; Basturk, A.; Dagli, M.[Abstract not Available]Öğe EVALUATION OF BONE MINERAL DENSITY AND PARAMETERS RELATED TO BONE METABOLISM IN HEMOPHILIC PATIENTS(PERGAMON-ELSEVIER SCIENCE LTD, 2017) Dağlı, M.; Kutlucan, A.; Abuşoğlu, Sedat; Baştürk, A.; Sözen, Mehmet; Kutlucan, L.; Ünlü, Ali[Abstract not Available]Öğe THE IMPORTANCE OF HIGH PLATELET-LYMPHOCYTE RATIO ON PROGNOSIS, DURATION OF HOSPITALISATION AND DEVELOPMENT OF HOSPITAL INFECTION AMONG INTENSIVE CARE PATIENTS(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Kutlucan, L.; Kutlucan, A.; Basturk, A.; Gur, M.; Senocak, E.[Abstract not Available]Öğe IRON DEFICIENCY ANEMIA INDUCED THROMBOCYTOPENIA: A CASE REPORT(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Baştürk, A.; Ayhan, M.; Akıncı, S.; Hacıbekiroğlu, T.; Güney, T.; Kutlucan, A.; Dilek, I.[Abstract not Available]Öğe MANTLE CELL LYMPHOMA PRESENTING WITH ACUTE APPENDICITIS(PERGAMON-ELSEVIER SCIENCE LTD, 2015) Baştürk, A.; Eren, S.; Akıncı, S.; Hacıbekiroğlu, T.; Güney, T.; Kutlucan, A.; Ecirli, S.[Abstract not Available]Öğe PARAVERTEBRAL EXTRAMEDULLARY HEMATOPOIESIS IN A PATIENT WITH THALASSEMIA INTERMEDIA(PERGAMON-ELSEVIER SCIENCE LTD, 2017) Kutlucan, A.; Dagli, M.; Kutlucan, L.; Kuku, M.; Basturk, A.[Abstract not Available]Öğe The predictive effect of initial complete blood count of intensive care unit patients on mortality, length of hospitalization, and nosocomial infections(VERDUCI PUBLISHER, 2016) Kutlucan, L.; Kutlucan, A.; Basaran, B.; Dagli, M.; Basturk, A.; Kozanhan, B.; Gur, M.OBJECTIVE: The mean platelet volume (MPV) can be used as an indicator of platelet activation. However, it has been shown that the platelet/lymphocyte ratio (PLR) can provide useful predictive information about inflammation and aggregation pathways. The neutrophil/lymphocyte ratio (NLR) may also be helpful as a marker of systemic or local inflammation. The main objective of this study evaluated to unselected critically ill patients the relationship of initial MPV, NLR, and PLR with mortality, length of hospitalization, and the risk of developing nosocomial infections in ICU patients. PATIENTS AND METHODS: In this retrospective study, we evaluated consecutive patients at our tertiary nine-bed ICU. One hundred seventy-three patients who were followed up during a 1-year period were included. RESULTS: MPV levels were found to be higher in patients who died in the hospital (p = 0.05). In addition, there was a significant positive correlation between expected mortality rate and MPV among non-survivors (p = 0.009). NLR levels were higher among non-survivors, but this difference was not statistically significant (p = 0.435). PLR levels were similar between non-survivors and survivors (p = 0.173). The initial NLR and PLR were significantly higher in patients with nosocomial infections. NLR and PLR had a significant positive correlation with length of hospitalization (p = 0.006 and p = 0.027, respectively). CONCLUSIONS: In our study, we found that high PLR and NLR may be indicators for the development of nosocomial infections. Moreover, the length of hospitalization may be prolonged in patients with high PLR and NLR.Öğe Prognostic significance of flow cytometry findings in Turkish adult acute leukemia patients(VERDUCI PUBLISHER, 2015) Baştürk, A.; Akıncı, S.; Hacıbekiroğlu, T.; Güney, T.; Kutlucan, A.; Ceran, F.; Akalın, S. D.OBJECTIVE: Several factors are known to affect prognosis of acute leukemia such as age, high leukocyte count, cytogenetic abnormality, performance status and recurrent leukemia. We aimed to investigate the association between cell surface markers and prognostic determinants such as recurrence at 6 and 12 months and survival at 6, 12 and 18 months in acute leukemia patients. PATIENTS AND METHODS: A total of 142 patients, 101 with acute myeloid leukemia (AML) and 41 with B-cell acute lymphoblastic leukemia (B-ALL) were included. The effects of surface markers on survival and recurrence rates were evaluated retrospectively. RESULTS: In AML patients, CD5+ and CD34+ immunophenotypes and in ALL patients cCD22+, CD34+ and CD49f + CD19+ immunophenotypes were positive prognostic indicators. In AML patients CD7 expression, and in ALL patients CD5+, CD7+ and CD117+ immunophenotypes and >90% CD45 expression were negative prognostic indicators. CONCLUSIONS: This study demonstrates that flow cytometry, a common diagnostic tool in acute leukemia, may also have prognostic value in acute leukemia in the future.Öğe SECONDARY ACUTE LYMPYHOBLASTIC LEUKEMIA DEVELOPED AFTER REFRACTORY LEIOMYOSARCOMA(PERGAMON-ELSEVIER SCIENCE LTD, 2017) Kutlucan, A.; Kutlucan, L.; Basturk, A.; Dagli, M.; Tras, G.[Abstract not Available]Öğe SEVERE RENAL FAILURE DUE TO HIGH DOSE METHOTREXATE IN ACUTE LYMPHOBLASTIC LEUKEMIA ASSOCIATED WITH PREDISPOSING FACTORS: CASE REPORT(PERGAMON-ELSEVIER SCIENCE LTD, 2014) Dagli, M.; Basturk, A.; Kutlucan, L.; Copur, B.; Kutlucan, A.; Sahin, F.[Abstract not Available]Öğe THYROZINE KINASE INHIBITORS IN CENTRAL NERVOUS SYSTEM RELAPSE OF A CHRONIC MYELOID LEUKEMIA: A CASE REPORT(PERGAMON-ELSEVIER SCIENCE LTD, 2017) Dagli, M.; Basturk, A.; Kutlucan, A.; Kutlucan, L.[Abstract not Available]
