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Öğe Effect of fixed appliances on oral malodor(MOSBY-ELSEVIER, 2011) Babacan, Hasan; Sokucu, Oral; Marakoglu, Ismail; Ozdemir, Hakan; Nalcaci, RuhiIntroduction: The objective of this study was to evaluate the effect of fixed appliances on oral malodor. Methods: Forty-one patients participated in this study. They were randomized into 2 groups: treated with fixed orthodontic appliances and untreated controls. Oral malodor measurements and the gingival and plaque indexes were recorded in each group by same periodontist. Measurements were taken from the study group before bonding, 1 week after bonding, and 4 weeks after bonding. The control group's measurements were made at the same time. Results: Oral malodor and the gingival and plaque indexes were significantly increased 1 week after bonding (P < 0.05). Oral malodor was increased at 4 weeks after bonding (P > 0.05). The comparison of the groups showed differences 1 week and 4 weeks after bonding. Conclusions: The oral malodor reached the critical level during fixed orthodontic treatment. Oral malodor could indicate a need to evaluate oral health and remind patients of the importance of maintaining ideal oral hygiene. (Am J Orthod Dentofacial Orthop 2011;139:351-5)Öğe Peri-implant crevicular fluid levels of cathepsin-K, RANKL, and OPG around standard, short, and mini dental implants after prosthodontic loading(KOREAN ACAD PERIODONTOLOGY, 2015) Alan, Raif; Marakoglu, Ismail; Haliloglu, SeyfullahPurpose: Despite the high success rates of endosseous dental implants, their placement is restricted according to the height and volume of bone available. The use of short or mini dental implants could be one way to overcome this limitation. Thus, this study aimed to compare standard, short, and mini dental implants with regard to associated clinical parameters and pen-implant crevicular fluid (PICF) levels of cathepsin-K (CTSK), RANK ligand (RANKL), and osteoprotegerin (UPS), after prosthodontic loading. Methods: A total of 78 non-submerged implants (Euroteknika, Aesthetica(+2), Sallanches, France) were installed in 30 subjects (13 male, 17 female; range, 26-62 years) who visited the clinic of the Periodontology Department Faculty of Dentistry, Selcuk University. Sampling and measurements were performed on the loading date (baseline) and 2, 14, and 90 days after loading. Assessment of the pen-implant status for the implant sites was performed using the pocket probing depth (PPD), modified plaque index, modified gingival index, modified sulcular bleeding index, and radiographic signs of bone loss. PICF samples collected from each implant were evaluated for CTSK, RANKL, and UPS levels using the ELISA method. Keratinized tissue and marginal bone loss (MBL) were also noted. Results: Clinical parameters statistically significantly increased in each group but did not show statistical differences between groups without PPD. Although implant groups showed a higher MBL in the upper jaw, only the standard dental group demonstrated a statistically significant difference. At 90 days, the OPG:sRANKL ratio and total amounts of CTSK for each group did not differ from baseline. Conclusions: Within the limitations of this study, both short and mini dental implants were achieving the same outcomes as the standard dental implants in the early period after loading.Öğe Periodontitis as a risk factor for preterm low birth weight(YONSEI UNIV COLLEGE MEDICINE, 2008) Marakoglu, Ismail; Gursoy, Ulvi Kahraman; Marakoglu, Kamile; Cakmak, Hulya; Ataoglu, TamerPurpose: There is growing evidence showing that a number of complex human diseases are caused or are at least influenced by periodontal diseases. Such diseases include cardiovascular diseases, respiratory diseases, diabetes mellitus and osteoporosis. The aim of study was to evaluate periodontal diseases as a risk factor for a preterm low birth weight. Materials and Methods: A total of 48 mothers, 20 of who had a preterm low birth weight delivery, were examined in the Clinics of Periodontology, Faculty of Dentistry, Cumhuriyet University. The periodontal exams consisted of a full mouth pocket depth, a Loe and Sillness Gingival index score measurements, and a panoramic radiograph analysis. Information on any other factors that may cause a preterm low birth weight was obtained from the family physician. Results: The study results indicated that periodontitis (OR: 3.6 95% CI: 1.06 - 12.18) together with bacterial vaginosis (OR: 11.57 95% CI: 1.26 - 105.7) were independent risk factors of a preterm low birth weight. According to the data obtained from this study, the paternal age, tobacco use and the mothers' height were not significant risk factors for a preterm low birth weight. Conclusion: Within the limits of this study, it is concluded that a poor periodontal health status of the mother may be a potential risk factor for a preterm low birth weight.Öğe The recurrent aphthous stomatitis frequency in the smoking cessation people(SPRINGER HEIDELBERG, 2007) Marakoglu, Kamile; Sezer, Recep Erol; Toker, Hulya Cakmak; Marakoglu, IsmailThis study was aimed to evaluate the frequency of recurrent aphthous stomatitis ( RAS) within the 6-week period after quitting smoking. The study group consisted of 90 subjects. Oral, medical findings and tobacco habits were recorded for all subjects. Nicotine replacement therapy (NRT) and behavioral treatment were applied to some of the subjects by a family physician. All subjects were evaluated for their RAS and periodontal measurements on baseline, 1, 3, 6 weeks by a periodontist. While the subjects were in this smoking cessation programme, 64 of the 90 smokers successfully quit smoking within the 6 weeks and 26 smokers dropped out during the third week of the study. Point prevalence of RAS among the subjects on the first day of the quitting period and at the end of the first, third and sixth week after smoking cessation was 3.3% (3/ 90), 18.9% (17/ 90), 21.1% (19/ 90) and 17.1 (11/64), respectively. In the following weeks, aphthous ulcer point prevalence was significantly higher than the quitting level ( p < 0.05). As the time after quitting increased, the incidence of aphthous ulcer decreased. Of 64 patients, 35 (54.6%) completed the 6 weeks using NRT and 29 (45.4%) of them did not use any medication. The aphthous ulcer frequency observed in the patients taking NRT [11.4% (4/35)] was lower when compared with the subjects taking no NRT [24.1% (7/29)] ( p > 0.05). The results of this study confirm that RAS is a complication of quitting smoking. Further studies are needed to identify the effects of NRT on RAS.Öğe Relationship between neutrophil functions and severity of periodontitis in obese and/or type 2 diabetic chronic periodontitis patients(QUINTESSENCE PUBLISHING CO INC, 2008) Gursoy, Ulvi Kahraman; Marakoglu, Ismail; Oztop, A. YaseminObjectives: Obesity and diabetes are the most common nutritional and endocrine disorders in developed and developing countries and are related to immune response alterations. Recent studies suggest an association among diabetes, obesity, and periodontitis. The aim of this study was to evaluate the relationship between neutrophil function alterations and periodontal disease severity of type 2 diabetic chronic periodontitis patients with and without obesity. Method and Materials: A total of 39 chronic periodontitis patients participated in the study. The study population was divided into 4 groups according to body mass index and type 2 diabetes status: (1) 8 type 2 diabetic obese patients, (2) 12 type 2 diabetic patients, (3) 8 obese patients, and (4) 11 systemically healthy patients as a control group. Neutrophil chemotaxis and phagocytosis functions and periodontal status were evaluated. Results: No differences in age, Gingival Index, Plaque Index, percentage of phagocytosis, phagocytic efficiency, and intracellular killing were observed among the groups, but chemotaxis was significantly lower in diabetic groups than the control group and probing depth was significantly higher in diabetic groups than the control group. Obesity did not seem to affect the results significantly for all parameters evaluated. Conclusions: Unlike in patients with type 2 diabetes, neither neutrophil functions nor periodontitis severity seemed to change in obese patients. However, in type 2 diabetic patients, neutrophil chemotaxis alterations seem to affect probing depth measurements.Öğe Smokers melanosis: A case report(EUROPEAN PUBLISHING, 2018) Taghizadeh, Sina; Dincer, Zeynep; Marakoglu, Ismail[Abstract not Available]Öğe Smoking status and smoke-related gingival melanin pigmentation in army recruitments(OXFORD UNIV PRESS, 2007) Marakoglu, Kamile; Guersoy, U. Kahraman; Toker, Huelya Cakmak; Demirer, Serhat; Sezer, R. Erol; Marakoglu, IsmailThis study aimed to define the smoking status and smoke-related gingival melanin pigmentation in army recruitments and was conducted with army recruitments in Sivas. Nine hundred eight subjects were examined. The oral and dental health of those subjects was checked and recorded. The smoking status of the subjects was self-reported and recorded on questionnaires by researchers. The chi(2) test and Kruskal-Wallis test were used for statistical analysis. More than one-half of the subjects (54.3%) were primary school graduates and the mean age was 20.2 +/- 0.95 years. The response rate regarding smoking was 100%. Of the respondents, 596 (65.7%) were current smokers, 12 (1.3%) were former smokers, and 300 (33.0%) were never smokers. The gingival melanin pigmentation rate was 27.5% in current smokers and 8.6% in those who never smoked (p=0.000). Smoking five to nine cigarettes a day appeared to be sufficient to cause gingival melanin pigmentation. The proportion of smokers who had melanin pigmentation did not change after 10 cigarettes a day. A rehabilitation project on smoking prevention and smoking cessation for army recruitments is urgently needed.
