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Öğe Activated Partial Thromboplastin Time and Prothrombin Time in Cows With Left Displaced Abomasum(Indian Veterinary Journal, 2003) Oğurtan, Zeki; Ok, Mahmut ; İzci, Celal; Ceylan, C.[Abstract not Available]Öğe Akkaraman ırkı ikiz kuzuda hypospadiasis(2005) Uyaroğlu, Ayşen; Oğurtan, ZekiSunulan bu çalışmada klinik muayenesi yapılan Akkaraman, erkek, ikiz kuzuda tespit edilen hypospadiasis olgusu değerlendirildi.Öğe Asıf Teori ve Tekni?ği? II. Bölüm: Plaka ve Vi?daların Çeşi?tli? Kırıklarda Asıf Metoduna Göre Farklı Uygulama Yöntemleri?(Selçuk Üniversitesi, 1997 Ocak) Oğurtan, Zeki; Alkan, FahrettinIn this part II, application of lag screw technique (interfragmental compression) with cancellous and cortex screws, axial compression and neutralization plate fixations with decompression plate, along with schematic fixation of various fractures, using ASIF techniques in small animals, have been outlined to guide the veterinary surgeons.Öğe Asıf Teori ve Tekniği The Theory and Technique Of Asıf 1. Bölüm(Selçuk Üniversitesi, 1996) Oğurtan, Zeki; Alkan, FahrettinAS IF has been In the use ol veterınary surgeons for a long perıod of time for lracture tixation in smail and ıarge anımals. Because of the intensty i of ASIF, it would be discussed ın two parts In thıs Part ı. the purpose. instrumentatıon and prıncıples ol the use of the ASIF have been outlined wıth the intentıon of guidıng veterinary swgeons.Öğe Bi?r Alman Çoban Köpeği?nde Panosteitis Vakasının Sağaltımı ve Radyoloji?k Taki?bi?(Selçuk Üniversitesi, 1999) Koç, Yılmaz; Alkan, Fahrettin; Birdane, Fatih M.; Oğurtan, ZekiIn this case report, clinical and radiologic follow-up of panosteitis was described in a German Shephard dog. The cause of panosteitis is unknown. Panosteitis occurs especially in young large or giant breeds of dogs. The diagnosis of panosteitis is confirmed through clinical, radiolagical and laboratuary findings. Flunixine meglumine were used to treat the disease.Öğe Bir buzağıda ectrodactyly ile birlikte şekillenmiş micromelia(1997) Alkan, Fahrettin; Tuzcu, Mehmet; Koç, Yılmaz; Oğurtan, ZekiBu vaka takdiminde melez bir erkek buzağıda görülen ectrodactyly ile birlikte şekillenmiş micromelia tanımlandı. Ruminantlardaki kongenital anomaliler kalıtsal, çevresel, yada her iki faktörün müşterek etkilerinin bir sonucu olarak ortaya çıkar.Ectrodactyly muhtemelen genetik olup, evcil hayvanlarda nadiren görülür.Öğe Bir Buzağıda Paralumbal Bölgede Heteretopik Akciğer Olgusu(Selçuk Üniversitesi, 1998) Koç, Yılmaz; Oğurtan, Zeki; Tuzcu, Mehmet; Alkan, Fahrettin; Çiftçi, M. KemalIn this study, heterotypic pulmonar anomaty in a two-day-old lemale calf was desenbed. Relaled clinical. radiological and histopathological results were discussed. The heterotypic pulmonar anomaly developed in the left paralumbar region, resulled in depression on the medulla spinalls, hemivertebra in L4, and scoliosis in L.4.5 .Öğe Bir Kangal Köpekte Hipertrofik Pulmonar Osteopati(2006) Oğurtan, ZekiKangal ırkı bir köpekte iskelet sisteminin kafatası, mandibula, maksilla, skapula, pelvis, uzun ve diğer kemiklerindeki periost ossifikasyonu ve akciğerde tümöral kitleler ile birlikte hipertofık osteopati tanısı konulan vaka tanımlandı.Öğe Bir kedide parsiyal coccygeal vertebra agenesisi(2005) Oğurtan, Zeki; Uyaroğlu, AyşenBir kedide parsiyel kuyruk vertebrası noksanlığı tanımlandı.Öğe Chitosan film containing fucoidan as a wound dressing for dermal burn healing: Preparation and in Vitro/In vivo evaluation(SPRINGER, 2007) Sezer, Ali Demir; Hatipoğlu, Fatih; Cevher, Erdal; Oğurtan, Zeki; Baş, Ahmet Levent; Akbuğa, JulideThe aim of this study was to develop chitosan film containing fucoidan and to investigate its suitability for the treatment of dermal burns on rabbits. Porous films, thickness between 29.7 and 269.0 mu m, were obtained by the solvent dropping method. Water vapor permeability (3.3-16.6/0.1 g), the swelling (0.67-1.77 g/g), tensile strength (7.1-45.8 N), and bioadhesion (0.076-1.771 mJ/cm(2)) of the films were determined. The thinnest films were obtained with the lowest chitosan concentration (P < .05). The water absorption capacity of the films sharply increased with the freeze-drying technique. The film having the thickness of 29.7 mu m showed the highest amount of moisture permeability (16.6 g/0.1 g). Higher chitosan concentration significantly increased tensile strength of the films (P < .05). Using higher concentration of lactic acid made films more elastic and applicable, and these films were selected for in vivo studies. Seven adult male New Zealand white rabbits were used for the evaluation of the films on superficial dermal burns. Biopsy samples were taken at 7, 14, and 21 days after wounding, and each wound site was examined macroscopically and histopathologically. After 7 days treatment, fibroplasia and scar were observed on wounds treated with fucoidan-chitosan film. The best regenerated dermal papillary formation, best reepithelization, and the fastest closure of wounds were found in the fucoidan-chitosan film treatment group after 14 days compared with other treatment and control groups. It can be concluded that fucoidan-chitosan films might be a potential treatment system for dermal burns and that changing formulation variables can modulate the characterizations of the films.Öğe Compararative Study of Bursting and Tensile Strengths of Digestive Tract in the Dog - Application to Esophago-Intestinal Sutures(ECOLE NATIONALE VETERINAIRE TOULOUSE, 2001) Oğurtan, Zeki; Gezici, Memduh; Kul, Mustafa; Ceylan, Cengiz; Alkan, FeyzanurThe resistance to tractive and pressure forces of digestive tract has been tested in the dog, The digestive tract was divided into several sections which are examined, and the results are compared with previously done anastomoses, in order to reduce postoperative complications.Öğe Compararative Study of Bursting and Tensile Strengths of Digestive Tract in the Dog: Application to Esophago-İntestinal Sutures(2001) Oğurtan, Zeki; Gezici, Memduh; Kul, Mustafa; Ceylan, Cengiz; Alkan, FeyzanurThe resistance to tractive and pressure forces of digestive tract has been tested in the dog. The digestive tract was divided into several sections which are examined, and the results are compared with previously done anastomoses, in order to reduce postoperative complications.Öğe Comparative Evaluation of Demineralized and Mineralized Xenogeneic Bovine Bone Powder and Chips on the Healing of Circumscribed Radial Bone Defects in the Dog(2007) Oğurtan, Zeki; Hatıpoğlu, Fatih; Ceylan, CengizKöpeklerin radiusunda yapılan dairesel defeklerde demineralize ve mineralize xenogenik sığır tozu ve partiküllerinin 2, 4, 6, 8 ve 12. haftalardaki iyileşme seyirleri karşılaştırmalı olarak değerlendirildi. Yabancı cisim reaksiyonu ve herhangi bir postoperatif yan etkiye rastlanmadı. Demineralize sığır xenogenik kemik tozu ile doldurulan defeklerin diğer formlardaki graf ile doldurulan defek iyileşmelerine göre daha fazla kemik dokusu oluşturması demineralizasyon ile birlikte graf ölçü küçüklüğünün önemini ortaya koymaktadır. Demineralize ve mineralize xenogenik kemik tozu ile partiküllerinin kemik iyileşmesi ve oluşum özelliklerinin karşılaştırılması demineralize kemik tozu lehine açık bir şekilde alan fenomeni farklılığını göstermektedir. Bu bulgulara dayanarak, türe özgü olmayan demineralize xenogenik sığır kemik tozunun verici olarak çok geniş hayvan kaynaklarının bulunması, kolay uygulanması, hazırlanması ve depolanabilme özelliği iyi bir graf materyali olduğunu ifade etmektedir.Öğe Comparative Holding Strength Between Partially Threaded Tipped and Nonthreaded Tipped Pins for Fracture Fixation in the Canine Femur: Histologic Results(2002) Oğurtan, ZekiBu çalışma, kırık oluşturulan ve oluşturulmayan köpek femurlarında ucu yivli ve yivsiz pin uygulamasının spongioz kemikte etkilerini araştırmak amacıyla gerçekleştirildi. İntramedullar pinin kemik dokusuna uygulanıp akabinde uzaklaştırılmasından sonra, kemik dokusunda oluşturduğu etkinin biyolojik faktörlerden ziyade mekaniksel olduğu tespit edildi. Ucu yivli pinlerin kırık femurlarda kırık oluşturulmayan femurlardakinden daha fazla hasar meydana getirdiği bulundu. Dördüncü haftada kırık femurlara uygulanan ucu yivli pinlerin yivleri içerisine aşırı miktarda kemik dokusu üremesi ile birlikte kemik dokusu ölümüne rastlandı. Osteoklastik aktiviteye rağmen yoğun kemik dokusu rezorpsiyonuna rastlanmadı. Kırık oluşturulmayan femurlarda daha az kemik dokusu ve daha fazla kemik iliği oluşumuna rastlandı. Kırık ve kırık oluşturulmayan femurlara uygulanan ucu yivsiz pinlerin ise sınırlı bir osteoklastik aktivite ve fibröz doku oluşumuna sebep olduğu tespit edildi. Sekizinci haftada kırık ve kırık oluşturulmayan femurlara uygulanan ucu yivli pinlerin oluşturduğu kemik dokusunun remodeling aktivitesi ile birlikte uzaklaştırılarak yerini fibröz dokusuna bıraktığı tespit edildi. Kırık kemiklerde aynı zamanda aşırı miktarda doku yivi rezorpsiyonu (kemik dokusu yivlerinin yüksekliğinin azalması) ve kemik dokusu ölümüne rastlandı.Öğe The Effect of Alkanna Tinctoria Tausch on Burn Wound Healing in Rabbits(M H Schaper Gmbh Co Kg, 2002) Oğurtan, Zeki ; Hatipoğlu, Fatih; Ceylan, C.Eighteen adult male New Zealand White rabbits were used in the treatment of partial thickness, severe and olive oil burns. Both right and left sides of the animals were burned to make partial thickness, severe and hot olive oil burn wounds. The solution of A. tinctoria TAUSCH in 16 % prepared in medical olive oil in weight basis, were applied to the left, and right side served as control. It was topically applied twice a day by gently rubbing against the burn area. While complete healing of partial thickness and olive oil burn wounds occurred in 7 to 10, and 26 days, respectively, with well formed dermal-epidermal junctions in both groups, severely burned wounds appeared to be nonresponsive to A. tinctoria.Öğe Effect of Experimental Therapeutic Ultrasound on the Distal Antebrachial Growth Plates in One-Month-Old Rabbits(Bailliere Tindall, 2002) Oğurtan, Zeki; Çelik, İlhami; İzci, Celal; Boydak, Murat; Alkan, Fahrettin; Yılmaz, KoçThe effect of therapeutic ultrasound (US) on the growth plates of growing bone was determined through fluorescence labelling and histopathological evaluation in one-month-old rabbits. Mean growth rates and mean heights of the growth plates of the US exposed radius vs. control radius, and US exposed ulna vs. control ulna showed no statistically significant differences at all intensities and time intervals. Mean growth rates and heights of the growth plates of the US exposed radius for 0.2 W/cm(2) (SATA) US vs. 0.5 W/cm(2) US showed the same type of pattern compared to those of the control radius for 0.2 W/cm(2) vs. 0.5 W/cm(2) at days 10, 15 and 20. Similar results were also found for the ulna. Effects of 0.5 W/cm(2) US on the mean growth rates and mean heights of the growth plates were superior to those of 0.2 W/cm(2) US at day 10. The results at day 10 were reversed for the same comparisons at days 15 and 20. No cavitation effect of US was observed on growth plate cells. There was no evidence of partial or complete premature closure of the growth plates or of angular deformity of the carpal region.Öğe Effect of Xylazine-Ketamine and Diazepam-Ketamine Anesthesia on Activated Partial Thromboplastin Time, Prothrombin Time and Bleeding Time in Dogs(Ecole Nationale Veterinaire Toulouse, 2002) Oğurtan, Zeki; Ceylan, C.; İpek, H.; İzci, CelalThe effects of xylazine ketamine and diazepam-ketamine on activated partial thromboplastin time (APTT), prothrombin time (PT) and buccal mucosa bleeding time (BMBT) were evaluated in dogs. Altered APTT, PT and BMBT values were found in xylazine-ketamine and diazepam ketamine anesthesia. Comparison of xylazine-ketamine to diazepam ketamine revealed a significant increase for APTT, PT at 30, 60 and 90 minutes and for BMBT at 30 and 60 minutes.Öğe Effects of Hyperosmolar Ionic and Low Osmolar Non-ionic Contrast Media on Coagulation Times and Some Blood Parameters in Dogs: an in Vivo Study(Wiley, 2003) İzci, Celal; Oğurtan, Zeki; Ceylan, C.The purpose of this study is to evaluate the effects of hyper-osmolar ionic contrast media (CM) (diatzioate) and low osmolar non-ionic CM (iohexol and ioxilan) on coagulation time and some blood parameters in dogs in vivo. The animals were divided into three groups in equal numbers. The dogs in groups 1, 11 and III received diatrizoate, iohexol and ioxilan at the dose of 700 mgI/kg intravenously (IV) as a bolus, respectively. Administration of contrast media and blood samples were collected from vena cephalica antebrachii prior to CM administration and thereafter at 3, 15, 30, 60, 90 and 180 min and 24 h to measure the coagulation factors [activated partial thromboplastin time (APTT), prothorombin time (PT), fibrinogen and fibrinogen degradation products] and some other blood parameters [red blood cells, platelet, white blood cells, haematocrit (Ht) and haemoglobin (Hb)]. While a statistically significant decrease was observed on APTT at 15 min in group III, no significant differences were found in groups I and II. All the groups had insignificant alterations for PT, fibrinogen and fibrinogen degradation product, following CM administration. Significant decreases were observed for platelet at 3 min in all groups. This decrease was also significant at 15- and 30- min intervals in group I. There were significant decreases for erythrocytes, Ht and Hb measurements within 30 min, and no significant alterations were observed for leucocytes within 60 min in all groups compared with baseline values. No differences were observed with regard to coagulation times and some blood parameters as far as long-lasting and major effects of each CM are concerned.Öğe Evaluation of fucoidan-chitosan hydrogels on superficial dermal burn healing in rabbit: An in vivo study(ELSEVIER SCIENCE BV, 2005) Sezer, Ali Demir; Hatipoğlu, Fatih; Oğurtan, Zeki; Baş, Ahmet Levent; Akbuğa, Julide[Abstract not Available]Öğe Histologic Characteristics and Local Cellular Immunity of the Gland of the Third Eyelid After Topical Ophthalmic Administration of 2% Cyclosporine for Treatment of Dogs With Keratoconjunctivitis Sicca(Amer Veterinary Medical Assoc, 2002) İzci, Celal; Çelik, İlhami; Alkan, Fahrettin; Oğurtan, Zeki; Ceylan, Cengiz; Sur, Emrah; Özkan, YaseminObjective-To evaluate the efficacy of topical administration of a 2% solution of cyclosporine (CsA) for treatment of dogs with keratoconjunctivitis sicca (KCS) and to correlate results with histopathologic characteristics and local cellular immunity of the gland of the third eyelid. Animals-24 dogs with bilateral KCS. Procedure-Lacrimal secretion was measured, using Schirmer tear test (STT) strips. Leukocyte and T-lymphocyte subsets were determined in blood samples. Histopathologic changes as well as CD4+, CD8+, and alpha-naphthyl-acetate esterase-positive (ANAE+) lymphocytes were evaluated. Results-Clinical signs resolved at the end of 1 month in conjunction with significantly increased STT values, compared with baseline values. Fifteen and 30 days after discontinuation of CsA treatment, a decrease was observed in STT values in both eyes; however, only values for the right eye were significantly different. There was a significant decrease in the number of lymphocytes and ANAE+ lymphocytes 15 and 30 days after discontinuation of CsA treatment, compared with baseline values. Differences were not observed in number of CD4+ lymphocytes among treatment groups. However, there was a significant decrease in number of CD8+ lymphocytes with reversal of the CD4+:CD8+ in both eyes after CsA treatment for 30 days, compared with the control group. Increased secretory activity and decreased lymphocyte infiltration were characteristic histopathologic findings. Conclusions and Clinical Relevance-Topical administration of a 2% solution of CsA was effective for the treatment of dogs with KCS. Strict follow-up monitoring is required after the cessation of treatment because of the possibility of recurrence of KCS.
