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Öğe Ilizarov External Fixation for Severely Comminuted Supracondylar and Intercondylar Fractures of the Distal Femur(British Editorial Soc Bone Joint Surgery, 2001) Arazi, M.; Memik, R.; Ogün, T. C.; Yel, M.Our aim was to determine the clinical effectiveness and safety of Ilizarov external fixation for the acute treatment of severely comminuted extra-articular and intercondylar fractures of the distal femur. A total of 14 consecutive patients with complex fractures was treated. There were three type-A3, two type-C2 and nine type-C3 fractures according to the AO/ASIF system. The mean follow-up was 14 months. Most fractures (13) united primarily at a mean of 16 weeks. One patient with a type-IIIA open fracture had infection and nonunion. The mean range of flexion of the knee at the final follow-up was 105 degrees (35 to 130). We conclude that, in the treatment of comminuted fractures of the distal femur, the Ilizarov fixator is safe and effective in providing stability and allowing early rehabilitation.Öğe Unreported "De Novo" Rearrangement of Chromosomes 4 and 7(MEDECINE ET HYGIENE, 2009) Yıldırım, M. S.; Ogün, T. C.Unreported "de novo" rearrangement of chromosomes 4 and 7: Unbalanced rearrangements of the chromosomes are extremely rare and associated with an abnormal phenotype and usually result in an abortion in early pregnancy. The current literature includes reports on the conditions related with rearrangements of chromosome 4 and 7. Herein, we describe a rearrangement between these two chromosomes, which is the first presentation of a specific translocation t(4;7)(q31;p15) and its consequent phenotype following de novo rearrangement of the chromosomes. It brought into light phenotypic similarities with other aberrations following breakage from adjacent band loci. We hope these features will help further genetic investigations on these chromosome regions.