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Öğe Beta-blocker treatment in an adolescent with amitriptyline intoxication(GALENOS YAYINCILIK, 2007) Baysal, Tamer; Oran, Buelent; Dogan, Mustafa; Cimen, Derya; Elmas, Sefika; Karaaslan, Sevim[Abstract not Available]Öğe Prediction of aortic diameter values in healthy Turkish infants, children and adolescents via Adaptive Network Based Fuzzy Inference System(SPRINGER-VERLAG BERLIN, 2008) Akdemir, Bayram; Gunes, Salih; Oran, BuelentThe aorta diameter size one of the cardiac value is very important to guess for child before adult age, due to growing up body. In conventional method, the experts use curve charts to decide whether their measured aortic diameter size is normal or not. Our proposed method presents a valid virtual aortic diameter result related to age, weight and sex. The proposed method comprises of two stages: (i) data normalization using a normalization method called Line Base Normalization Method (LBNM) that is firstly proposed by us, (ii) normalized aortic diameter prediction using Adaptive Network Based Fuzzy Inference Systems (ANFIS). Data set includes real Turkish infants, children and adolescents values and divided into two groups as 50% training -50% testing split of whole dataset to show performance of ANFIS. LBNM compared to three normalization methods including Min-Max normalization, Z-score, and decimal scaling methods. The results were compared to real aortic diameters values by expert with nine year experiences in medical area.Öğe Prediction of Aortic Diameter Values in Healthy Turkish Infants, Children, and Adolescents by Using Artificial Neural Network(SPRINGER, 2009) Akdemir, Bayram; Oran, Buelent; Gunes, Salih; Karaaslan, SevimThe aorta is the largest vessel in the systemic circuit. Its diameter is very important to guess for child before adult age, due to growing up body. Aortic diameter, one of the cardiac values, changes in time. Evaluation of the cardiac structures and generating a valid regional curve requires a large study group experience for accurate data on normal values. In this study, our aim is to estimate aortic diameter values without curve of charts. Using real sample of the all groups has been predicted using a hybrid system based on combination of Line Based Normalization Method (LBNM) and Artificial Neural Network (ANN) with Levenberg-Marquardt (LM) algorithm. In this study, aortic diameter values dataset divided into two groups as 50% training-50% testing of whole dataset. In order to show the performance of the proposed method, two fold cross validation and prevalent performance measuring methods, Mean Square Error (MSE), Absolute Deviation (AD), Root Mean Square Error (RMSE), statistical relation factor T and R-2, have been used. The obtained MSE results from combination of Min-Max normalization and ANN, combination of Decimal Scaling and ANN, combination of Z-score and ANN, and combination of LBNM and ANN (the proposed method) are 0.00517, 0.001299, 0.006196, and 0.000145, respectively. For the suggested method, error's results have been given discretely for every age up to adult age. The results are compared to real aortic diameter values by expert with nine year experiences in medical area. These results have shown that the proposed method can be confidently used in the prediction of aortic diameter values in healthy Turkish infants, children and adolescents.Öğe Prevalence and distribution of children with congenital heart diseases in the central Anatolian region, Turkey(TURKISH J PEDIATRICS, 2006) Baspinar, Osman; Karaaslan, Sevim; Oran, Buelent; Baysal, Tamer; Elmaci, A. Midhat; Yorulmaz, AlaaddinCongenital heart diseases (CHD) are the most frequent malformation at birth. The aims of this study were to assess the prevalence of congenital heart disease, their different types, and the detection rate among children in the central Anatolian region in Turkey. The study was conducted during an eight-year period (March 1995-December 2002). The prevalence of CHD in a large tertiary care hospital in the central Anatolian region in Turkey was studied. The diagnosis of a structural defect was based on echocardiographic study. The following age groups were considered: neonates, infants and toddlers, preschool children, schoolchildren, and adolescents. In the study period, 1,693 children were found to have CHD; 1,253 patients were neonates and infants. Total prevalence of CHD over the study period was 7.77 per 1,000 live-born. The prevalence increased from 6.35 to 9.65 per 1,000 live births between 1995 and 2002 (p<0.05). The average age at diagnosis was 2.2+/-3.64 years (I day to 18 years, median 5 months). There were 863 (51%) boys and 830 (49%) girls, with a male/female ratio of 1:1. Isolated ventricular septal defect (32.6%) was the most frequent acyanotic anomaly, and tetralogy of Fallot (5.8%) was the most frequent cyanotic anomaly. The commonest non-cardiac anomalies with CHD were musculoskeletal. anomalies. Down syndrome was determined in 83 patients (78.3%) from all syndromic CHD cases. Congenital heart disease is a very significant health problem. It requires urgent measures in terms of organization of early diagnosis and proper management. The prevalence rate is comparable to that of similar developed countries. Increasing incidence of CHD might be attributed to more diagnoses with new technologic development or it may indicate a real increase in the defects.Öğe Pulmonary arterial pressure in children with croup syndrome(W B SAUNDERS CO-ELSEVIER INC, 2006) Oran, Buelent; Ekici, Guelsuen; Reisli, Ismail; Arbag, Hamdi; Baspinar, Osman; Baysal, Tamer; Dogan, MustafaPurpose: Croup syndrome or laryngotracheitis is one of the frequent causes of transient upper airway obstruction by laryngeal and tracheal blockage in infants and children. Upper airway obstruction may lead to increased pulmonary arterial pressure in children. In this study, the relationship between croup syndrome and pulmonary arterial pressure was investigated. Materials and methods: Forty children with croup syndrome and 14 healthy, age- and sex-matched control Subjects were enrolled in this study. Of all patients, 12 with severe symptoms, such as dyspnea, cyanosis, hypoventilation, were accepted as "high croup score" (croup score >= 6). All patients with high croup score were treated with dexamethasone. We assessed pulmonary arterial pressure of patients during therapy using serial echocardiographic measurements. Results: Our results showed that children with croup syndrome have significantly higher pulmonary arterial pressures than healthy subjects at the time of diagnosis. Pressure values of patients with high croup score were found to be significantly higher when compared with those of the low -core group (P < .05). However, there was no difference between 2 groups at the end of therapy. Conclusions: It is Suggested that pulmonary arterial pressure increased to different extents in the acute stage of illness and that the degree of increase was related to the severity of disease and average hospital stay. In addition, increased pulmonary arterial pressure due to croup syndrome is reversible. Furthermore, evaluation of children with croup syndrome by using Doppler echocardiography may be useful in the monitoring of pulmonary arterial pressure and in the follow-up of their therapy. (C) 2006 Elsevier Inc. All rights reserved.
