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Öğe Anaesthetic and Haemodynamic Effects of Continuous Spinal Versus Continuous Epidural Anaesthesia With Prilocaine(Greenwich Medical Media Ltd, 2003) Reisli, Ruhiye; Çelik, J.; Tuncer, S.; Yosunkaya, Alper; Otelcioğlu, S.Background and objective: To compare, using prilocaine, the effects of continuous spinal anaesthesia (CSA) and continuous epidural anaesthesia (CEA) on haemodynamic stability as well as the quality of anaesthesia and recovery in patients undergoing transurethral resection of the prostate gland. Methods: Thirty patients (>60 yr) were randomized into two groups. Prilocaine, 2% 40 mg, was given to patients in the CSA group, and prilocaine 1% 150 mg was given to patients in the CEA group. Incremental doses were given if the level of sensory block was lower than T-10 or if needed during surgery. Results: There was a significant decrease in mean arterial pressure in Group CEA compared with Group CSA (P < 0.01). The decrease in heart rate in Group CSA occurred 10 min after the first local anaesthetic administration and continued through the operation (P < 0.05). The level of sensory anaesthesia was similar in both groups. The times to reach the level of T-10 and the upper level of sensory blockade (T-max) were 18.0 +/- 4.7 and 25.3 +/- 7.0 min in Groups CSA and CEA, respectively, and were significantly longer in Group CEA. The duration of anaesthesia was 76.8 +/- 4 min and was shorter in Group CSA (P < 0.01). Conclusions: Spinal or epidural anaesthesia administered continuously was reliable in elderly patients undergoing transurethral resection of the prostate. Continuous spinal anaesthesia had a more rapid onset of action, produced more effective sensory and motor blockade and had a shorter recovery period. Prilocaine appeared to be a safe local anaesthetic for use with either continuous spinal anaesthesia or continuous epidural anaesthesia.Öğe EEG Findings in Etomidate Anaesthesia(1992) Özmen, S.; Ökeşli, S.; İlhan, N.; Akhan, G.; Otelcioğlu, S.; Ünal, F.This study included 30 volunteer cases (19 male, 11 female) in ASA-I group with normal electroancephalographic findings. All cases divided in 3 groups randomly and 45 minutessd prior to administration of etomidate, first group was premedicated with 0.5 mg Atropine, second group with 0.5 mg Atropine and 10 mg Diazepam and third group with 0.5 mg Atropine and 01. mg Fentanyl. Induction has been succeeded by IV 0.4 mg/kg etomidate. In order to maintain anaesthesia 0.1 mg/kg etomidate was administered intravenously at 5th minute and EEG was obtained for 15 mintures after first dosage of etomidate. The EEG findings of etomidate anaesthesia and the relation of myoclonia (the main side effect) with CNS was evaluated by EEG records. EEG findings were not affected with premedication methods and no correlation between myoclonia and EEG signs was established. However, myoclonia was decreased significantly in patients who received Fentanyl as premedication. Instead of the irregular alpha and fast activities were observed on control EEG recordings in patients anaesthetised with etomidate. The sharp waves and the suppression burst activities appeared in some cases. In conclusion attention must be paid during etomidate anaesthesia in epileptic patients or it should be avoided using etomidate in patients who has a history of epilepsy because of the possibility of provocating the seizures.Öğe The Effects on Blood Glucose, İnsulin and Cortisol Levels of Using Etomidate and Thiopentone in IV Anaesthesia(1991) Okesli, S.; Özmen, S.; Otelcioğlu, S.; Gürbilek, M.; Karabacak, H.[Abstract not Available]Öğe Evaluation of Halothane and Sevoflurane Effects With Two Different Anaesthesia Induction Methods in Children [Çocukların Anestezi İndüksiyonunda Farklı İki Yöntem İle Uygulanan Halotan ve Sevofluranın Etkilerinin Değerlendirilmesi](2001) Yosunkaya, A.; Aydemir, T.; Tuncer, S.; Reisli, R.; Otelcioğlu, S.In this study, we compared the induction characteristics of halothane and sevoflurane with two different anaesthesia induction methods on eighty children (1-6 years old) ASA I-II class scheduled for elective surgery. None of the patients were premedicated. Patients were randomly assigned to four equal groups. Anaesthesia induction was achieved as follows: in 50 % O2/N2O, in Group I, starting with halothane 0.5 % concentration, increasing 0.5 % and reaching to 3.5 % maximum; in Group II, starting with sevoflurane 1 % concentration, increasing 1-1.5 % and reaching to 7 % maximum; in Group III, starting with 3.5 % and Group IV, starting with 7 % concentration. The duration of induction, it's completion, intubation and the complications which developed during induction were determined. Measurements of systolic arterial pressure, diastolic arterial pressure and heart rate were recorded before induction, after induction, after intubation, 3 and 5 minutes after intubation. The induction duration was determined shorter in Group III than Group I and in Group VI titan Group II (p<0.05). As there were significant differences for the duration of the induction between Group I and Group II while Group III and Group IV were similar (p?0.05). We didn't see a statistically difference between the groups regarding the completion of the induction, the duration of the intubation, and complications (p>0.05). As a result, sevoflurane was found to be a good alternative to halothane in paediatric patients and the induction with high concentration could be preferred because of the reliable and significantly faster induction.Öğe Intraperitoneal Versus Interpleural Analgesia on Post-Operative Pain to Laparoscopic Cholecystectomy(2000) Çelik, J.; Tuncer, S.; Reisli, R.; Ökeşli, S.; Otelcioğlu, S.In our study, we aimed to compare the quality and duration of analgesia intrapleural bupivacaine, bupivacaine+morphine, only morphine and intraperitoneal bupivacaine, bupivacaine+morphine and only morphine administration for relieving pain after laparoscopic cholecystectomy. 90 cases of ASA I-II class were included in the study. Cases were randomly allocated in six groups. At the end of surgery, Group I (n=15) intraperitoneal 3 mg morphine in 30 mL saline; Group II (n=15) intraperitoneal 30 mL % 0.25 bupivacaine; Group III (n=15) intraperitoneal 30 mL % 0.25 bupivacaine+3 mg morphine; Group IV (n=15) interpleural 3 mg morphine in 30 mL saline; Group V (n=15) interpleural 30 mL % 0.25 bupivacaine; Group VI (n=15) interpleural 30 mL % 0.25 bupivacaine+3 mg morphine were administered. Postoperatif pain was assesed by a visual analog scale, numeric rating scale in 1,2,4,6,12, 24 hours and side effect were recorded for 24 hours. Interpleural bupivacaine was effective for postoperative pain relief and adding morphine to bupivacaine does not increase the quality and duration of analgesia. There were no differences in intraoperative fentanyl consumption and postoperative pain scores (NRS, VAS) were less in groups V and VI than groups I,II,III,IV.